Collaboration, License and Research Agreements - Reconciliation of Deferred Revenue Related to Lilly Agreement (Details) - Research Collaboration and License Agreement with Eli Lilly - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2022	Dec. 31, 2021
Contract With Customer, Liability [Roll Forward]
Beginning balance	$ 11,108	$ 15,840
Revenue recognized	(4,933)	(4,732)
Beginning balance	$ 6,175	$ 11,108