Condensed Statements of Cash Flows (unaudited) - USD ($) $ in Thousands	6 Months Ended
	Jun. 30, 2022	Jun. 30, 2021
Cash flows from operating activities
Net loss	$ (79,925)	$ (50,197)
Adjustments to reconcile net loss to net cash used in operating activities:
Depreciation	636	255
Stock-based compensation expense	12,746	7,990
Amortization of premiums and discounts on marketable securities, net	223	69
Gain on disposal of property and equipment	0	(16)
Changes in operating assets and liabilities:
Prepaid and other assets	(251)	(4,394)
Accounts payable and accrued liabilities	6,582	579
Accrued compensation	(4,253)	151
Operating lease right-of-use assets and liabilities, net	1,128	299
Deferred revenue	(2,006)	(2,552)
Net cash used in operating activities	(65,120)	(47,816)
Cash flows from investing activities
Maturities of marketable securities	21,525	3,580
Purchases of marketable securities	(212,564)	0
Purchases of property and equipment	(2,080)	(1,233)
Net cash (used in) provided by investing activities	(193,119)	2,347
Cash flows from financing activities
Proceeds from issuance of common stock in public offerings, gross	64,313	0
Payment of issuance costs related to public offerings	(1,929)	0
Proceeds from issuance of common stock under employee stock purchase plan	499	318
Proceeds from exercise of stock options	14	122
Payment of deferred financing costs	0	(10)
Net cash provided by financing activities	62,897	430
Net decrease in cash, cash equivalents and restricted cash	(195,342)	(45,039)
Cash, cash equivalents and restricted cash at beginning of period	320,699	321,713
Cash, cash equivalents and restricted cash at end of period	125,357	276,674
Supplemental schedule of noncash investing and financing activities:
Costs incurred, but not paid, in connection with deferred financing costs included in accounts payable and accrued liabilities	0	90
Costs incurred, but not paid, in connection with purchases of property and equipment included in accounts payable and accrued liabilities	$ 0	$ 94