Condensed Statements of Stockholders' Equity (Unaudited) - USD ($) shares in Thousands, $ in Thousands	Total	Public Offering	Common Stock	Common Stock Public Offering	Additional Paid-in Capital	Additional Paid-in Capital Public Offering	Accumulated Other Comprehensive Loss	Accumulated Deficit
Balance at Dec. 31, 2020	$ 306,223		$ 4		$ 372,764		$ (5)	$ (66,540)
Balance, Shares at Dec. 31, 2020			37,569
Issuance of common stock upon exercise of stock options	24				24
Issuance of common stock upon exercise of stock options, Shares			31
Vesting of early exercise options	10				10
Stock-based compensation	3,701				3,701
Net loss	(23,844)							(23,844)
Other comprehensive gain (loss)	2						2
Balance at Mar. 31, 2021	286,116		$ 4		376,499		(3)	(90,384)
Balance, Shares at Mar. 31, 2021			37,600
Balance at Dec. 31, 2020	306,223		$ 4		372,764		(5)	(66,540)
Balance, Shares at Dec. 31, 2020			37,569
Net loss	(50,197)
Balance at Jun. 30, 2021	264,480		$ 4		381,213			(116,737)
Balance, Shares at Jun. 30, 2021			37,665
Balance at Mar. 31, 2021	286,116		$ 4		376,499		(3)	(90,384)
Balance, Shares at Mar. 31, 2021			37,600
Issuance of common stock upon exercise of stock options	98				98
Issuance of common stock upon exercise of stock options, Shares			51
Issuance of common stock under employee stock purchase plan	318				318
Issuance of common stock under employee stock purchase plan, Shares			14
Vesting of early exercise options	9				9
Stock-based compensation	4,289				4,289
Net loss	(26,353)							(26,353)
Other comprehensive gain (loss)	3						3
Balance at Jun. 30, 2021	264,480		$ 4		381,213			(116,737)
Balance, Shares at Jun. 30, 2021			37,665
Balance at Dec. 31, 2021	381,430		$ 5		566,161		(187)	(184,549)
Balance, Shares at Dec. 31, 2021			47,754
Issuance of common stock upon exercise of stock options	10				10
Issuance of common stock upon exercise of stock options, Shares			7
Vesting of early exercise options	1				1
Issuance of common stock in public offerings, net of issuance costs		$ 24,103				$ 24,103
Issuance of common stock in public offerings, net of issuance costs, Shares				1,520
Stock-based compensation	6,238				6,238
Net loss	(34,235)							(34,235)
Other comprehensive gain (loss)	(1,839)						(1,839)
Balance at Mar. 31, 2022	375,708		$ 5		596,513		(2,026)	(218,784)
Balance, Shares at Mar. 31, 2022			49,281
Balance at Dec. 31, 2021	$ 381,430		$ 5		566,161		(187)	(184,549)
Balance, Shares at Dec. 31, 2021			47,754
Issuance of common stock upon exercise of stock options, Shares	12
Net loss	$ (79,925)
Balance at Jun. 30, 2022	374,351		$ 5		641,806		(2,986)	(264,474)
Balance, Shares at Jun. 30, 2022			52,081
Balance at Mar. 31, 2022	375,708		$ 5		596,513		(2,026)	(218,784)
Balance, Shares at Mar. 31, 2022			49,281
Issuance of common stock upon exercise of stock options	4				4
Issuance of common stock upon exercise of stock options, Shares			5
Issuance of common stock under employee stock purchase plan	499				499
Issuance of common stock under employee stock purchase plan, Shares			49
Vesting of early exercise options	1				1
Issuance of common stock in public offerings, net of issuance costs		$ 38,281				$ 38,281
Issuance of common stock in public offerings, net of issuance costs, Shares				2,746
Stock-based compensation	6,508				6,508
Net loss	(45,690)							(45,690)
Other comprehensive gain (loss)	(960)						(960)
Balance at Jun. 30, 2022	$ 374,351		$ 5		$ 641,806		$ (2,986)	$ (264,474)
Balance, Shares at Jun. 30, 2022			52,081