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Statements of Cash Flows - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2021
Dec. 31, 2020
Dec. 31, 2019
Cash flows from operating activities      
Net loss $ (118,009) $ (44,355) $ (24,734)
Adjustments to reconcile net loss to net cash (used in) provided by operating activities:      
Depreciation 639 373 348
Stock-based compensation expense 17,056 4,310 406
Amortization of premiums and discounts on marketable securities, net 179 9 0
Amortization of discounts and loan issuance costs 0 29 71
Gain on disposal of property and equipment (16) 0 0
Noncash interest expense 0 110 7,027
Change in fair value of preferred warrant liability 0 75 15
Changes in operating assets and liabilities:      
Prepaid and other assets (2,510) (2,444) (949)
Accounts payable and accrued liabilities 6,043 5,749 436
Accrued compensation 5,788 1,838 1,010
Operating lease right-of-use assets and liabilities, net 461 289 (80)
Deferred revenue (4,444) (3,100) 18,940
Net cash (used in) provided by operating activities (94,813) (37,117) 2,490
Cash flows from investing activities      
Purchases of marketable securities (85,357) (6,693) 0
Maturities of marketable securities 6,580 0 0
Purchases of property and equipment (3,740) (1,092) (235)
Net cash used in investing activities (82,517) (7,785) (235)
Cash flows from financing activities      
Proceeds from issuance of common stock in public offerings, gross 185,939 298,080 0
Payment of issuance costs related to public offerings (11,262) (24,026) 0
Proceeds from exercise of stock/unit options, net of repurchases 930 22 65
Proceeds from issuance of common stock under employee stock purchase plan 709 444 0
Payments on long-term debt 0 (4,683) (2,800)
Distributions to members 0 0 (106)
Proceeds from issuance of Series C convertible preferred stock, net of issuance costs 0 2,200 72,623
Proceeds from issuance of convertible notes, net of issuance costs 0 0 19,451
Net cash provided by financing activities 176,316 272,037 89,233
Net (decrease) increase in cash, cash equivalents and restricted cash (1,014) 227,135 91,488
Cash, cash equivalents and restricted cash at beginning of period 321,713 94,578 3,090
Cash, cash equivalents and restricted cash at end of period 320,699 321,713 94,578
Supplemental disclosure of cash flow information:      
Cash paid for interest 0 571 322
Supplemental schedule of noncash investing and financing activities:      
Right-of-use assets obtained in exchange for operating lease liabilities 12,074 936 807
Costs incurred, but not paid, in connection with purchases of property and equipment included in accounts payable and accrued liabilities 220 118 43
Conversion of convertible preferred stock into common stock upon completion of initial public offering 0 136,920 0
Issuance of Series C convertible preferred stock upon conversion of outstanding convertible notes 0 0 29,510
Reclassification of warrant liability to equity due to adjustment from preferred stock warrant to common stock warrant upon completion of initial public offering $ 0 $ 120 $ 0