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Income Taxes - Reconciliation of Income Taxes Computed by Applying Statutory Federal Income Tax Rate (Details) - USD ($)
12 Months Ended
Dec. 31, 2021
Dec. 31, 2020
Dec. 31, 2019
Income Tax Disclosure [Abstract]      
Income tax expense (benefit) at statutory rates $ (24,784,000) $ (9,315,000) $ (5,194,000)
State income tax, net of federal benefit (7,868,000) (3,004,000) (1,057,000)
Permanent items 210,000 1,000 14,000
Book income for pre-conversion period 0 0 527,000
Interest on convertible notes 0 0 445,000
Realized gain on conversion of convertible notes 0 0 958,000
Reserve for uncertain tax positions 1,170,000 398,000 140,000
Research and development tax credits (4,792,000) (1,639,000) (584,000)
Deferred taxes recognized upon conversion 0 0 (3,076,000)
Valuation allowance 35,326,000 13,488,000 7,827,000
Other 738,000 71,000 0
Income tax expense (benefit) $ 0 $ 0 $ 0