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Stockholders' Equity (Deficit) - Schedule of Assumptions used in Black-Scholes Model to Determine Fair Value of Stock/Unit Option Grants and Shares Purchasable under ESPP (Details)
12 Months Ended
Dec. 31, 2021
Dec. 31, 2020
Dec. 31, 2019
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]      
Risk-free interest rate, Minimum 0.50% 0.30% 1.40%
Risk-free interest rate, Maximum 1.30% 1.50% 2.70%
Expected dividend yield 0.00% 0.00% 0.00%
Employee Stock Purchase Plan      
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]      
Risk-free interest rate, Minimum   0.10%  
Risk-free interest rate, Maximum   0.20%  
Expected term (in years) 6 months 6 months  
Expected dividend yield 0.00% 0.00%  
Risk-free interest rate 0.10%    
Minimum      
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]      
Expected volatility 86.00% 88.00% 84.00%
Expected term (in years) 5 years 6 months 5 years 4 months 24 days 2 years
Minimum | Employee Stock Purchase Plan      
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]      
Expected volatility 69.00% 75.00%  
Maximum      
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]      
Expected volatility 88.00% 92.00% 88.00%
Expected term (in years) 6 years 1 month 6 days 6 years 1 month 6 days 6 years 1 month 6 days
Maximum | Employee Stock Purchase Plan      
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]      
Expected volatility 75.00% 96.00%