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Statements of Operations and Comprehensive Loss - USD ($)
shares in Thousands, $ in Thousands
12 Months Ended
Dec. 31, 2021
Dec. 31, 2020
Dec. 31, 2019
Income Statement [Abstract]      
Collaboration revenue $ 9,326 $ 6,787 $ 2,319
Revenue from Contract with Customer, Product and Service [Extensible Enumeration] us-gaap:LicenseAndServiceMember us-gaap:LicenseAndServiceMember us-gaap:LicenseAndServiceMember
Operating expenses:      
Research and development $ 101,182 $ 37,602 $ 14,539
General and administrative 26,195 13,462 5,112
Total operating expenses 127,377 51,064 19,651
Loss from operations (118,051) (44,277) (17,332)
Other income (expense):      
Interest income 104 206 0
Interest expense 0 (209) (7,387)
Change in fair value of preferred warrant liability 0 (75) (15)
Other expense (62) 0 0
Total other income (expense) 42 (78) (7,402)
Net loss (118,009) (44,355) (24,734)
Other comprehensive income (loss):      
Net unrealized losses on marketable securities (182) (5) 0
Comprehensive loss $ (118,191) $ (44,360) $ (24,734)
Net loss per share/unit, basic and diluted $ (2.85) $ (2.05) $ (9.12)
Weighted-average shares/units outstanding, basic and diluted 41,428 21,663 2,713