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Condensed Statements of Operations (Unaudited) - USD ($)
shares in Thousands, $ in Thousands
3 Months Ended 6 Months Ended
Jun. 30, 2020
Jun. 30, 2019
Jun. 30, 2020
Jun. 30, 2019
Income Statement [Abstract]        
Collaboration revenue $ 1,541 $ 224 $ 2,899 $ 224
Revenue from Contract with Customer, Product and Service [Extensible List] rna:CollaborationRevenueMember rna:CollaborationRevenueMember rna:CollaborationRevenueMember rna:CollaborationRevenueMember
Operating expenses:        
Research and development $ 8,984 $ 2,533 $ 14,528 $ 3,795
General and administrative 2,925 1,596 4,889 2,508
Total operating expenses 11,909 4,129 19,417 6,303
Loss from operations (10,368) (3,905) (16,518) (6,079)
Other income (expense):        
Interest income 18 0 161 0
Interest and other expense (131) (1,215) (209) (1,587)
Change in fair value of preferred warrant liability (75) 4 (75) 1
Total other income (expense) (188) (1,211) (123) (1,586)
Net loss $ (10,556) $ (5,116) $ (16,641) $ (7,665)
Net loss per share, basic and diluted $ (1.23) $ (1.89) $ (2.91) $ (2.87)
Weighted-average shares outstanding, basic and diluted 8,586 2,704 5,715 2,669