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Akeso Collaboration and License Agreement (Details)
$ in Thousands, shares in Millions
1 Months Ended 2 Months Ended 3 Months Ended
Mar. 06, 2023
USD ($)
Jan. 31, 2023
USD ($)
shares
Mar. 06, 2023
USD ($)
Mar. 31, 2023
USD ($)
patient
Mar. 31, 2022
USD ($)
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]          
In-process research and development       $ 520,915 $ 0
Issuance of common stock in lieu of cash for Akeso upfront payment       $ 45,900  
Ivonescimab | China and Australia          
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]          
Number of patients dosed (over) | patient       750  
Collaborative arrangement, transaction with party to collaborative arrangement          
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]          
Collaborative arrangement, upfront payment     $ 500,000    
Cash payment for collaborative arrangement, upfront payment     474,900    
Collaborative arrangement, additional potential milestone payments   $ 4,500,000      
Collaborative arrangement, potential regulatory milestone payments   1,050,000      
Collaborative arrangement, potential commercial milestone payments   3,450,000      
Collaborative arrangement, direct transaction costs     $ 115    
Collaborative arrangement, transaction with party to collaborative arrangement, upfront payment one          
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]          
Cash payment for collaborative arrangement, upfront payment   $ 274,900      
Collaborative arrangement, common stock issued in lieu of cash upfront payment (in shares) | shares   10      
Collaborative arrangement, upfront payment, paid in shares   $ 25,100      
Issuance of common stock in lieu of cash for Akeso upfront payment   $ 45,900      
Collaborative arrangement, transaction with party to collaborative arrangement, upfront payment two          
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]          
Cash payment for collaborative arrangement, upfront payment $ 200,000