Goodwill and Intangible Assets - Schedule of acquired intangible assets (Details) - USD ($)	12 Months Ended
	Dec. 31, 2020	Dec. 31, 2021
Finite-Lived Intangible Assets [Line Items]
Gross	$ 20,170,000	$ 19,963,000
Accumulated amortization and impairment charges	(8,655,000)	(9,564,000)
Net	11,515,000	10,399,000
Software | Utrophin program
Finite-Lived Intangible Assets [Line Items]
Gross	4,534,000	4,487,000
Accumulated amortization and impairment charges	(4,534,000)	(4,487,000)
Net	0	0
Software | Discuva platform
Finite-Lived Intangible Assets [Line Items]
Gross	14,565,000	14,416,000
Accumulated amortization and impairment charges	(3,050,000)	(4,017,000)
Net	11,515,000	10,399,000
Option over non-financial asset
Finite-Lived Intangible Assets [Line Items]
Gross	921,000	912,000
Accumulated amortization and impairment charges	(921,000)	(912,000)
Net	0	0
Fair value of option over non-financial asset	0
Impairment of Intangible Assets, Finite-lived	859,000
Other patents and licenses
Finite-Lived Intangible Assets [Line Items]
Gross	150,000	148,000
Accumulated amortization and impairment charges	(150,000)	(148,000)
Net	$ 0	$ 0