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Subsequent events (Details Narrative) - $ / shares
Jan. 11, 2022
Dec. 31, 2021
Dec. 31, 2020
Apr. 10, 2015
Subsequent Event [Line Items]        
Class of warrant, outstanding   6,200,000    
Exercise price of warrants   $ 2.11 $ 2.11 $ 1.60
Common stock, shares, outstanding   22,850,947 22,850,947  
Series B Common Stock Warrants [Member]        
Subsequent Event [Line Items]        
Exercise price of warrants     $ 0.11  
Series D Common Stock Warrants [Member]        
Subsequent Event [Line Items]        
Exercise price of warrants     $ 1.60  
Chief Executive Officer [Member] | Series B warrants [Member]        
Subsequent Event [Line Items]        
Exercise price of warrants $ 1.60      
Chief Executive Officer [Member] | Series B Common Stock Warrants [Member]        
Subsequent Event [Line Items]        
Class of warrant, outstanding   87,456    
Subsequent Event [Member]        
Subsequent Event [Line Items]        
Common stock, shares, outstanding 22,941,357      
Subsequent Event [Member] | Chief Executive Officer [Member]        
Subsequent Event [Line Items]        
Exercise price of warrants $ 0.11      
Common stock, shares, outstanding 90,410      
Subsequent Event [Member] | Chief Executive Officer [Member] | Series B Common Stock Warrants [Member]        
Subsequent Event [Line Items]        
Class of warrant, outstanding 0      
Subsequent Event [Member] | Chief Executive Officer [Member] | Series D Common Stock Warrants [Member]        
Subsequent Event [Line Items]        
Class of warrant, outstanding 6,250,000      
Subsequent Event [Member] | Chief Executive Officer [Member] | Series B Common Stock Warrants [Member]        
Subsequent Event [Line Items]        
Class of warrant, outstanding 87,456      
Subsequent Event [Member] | Chief Executive Officer [Member] | Series D Common Stock Warrants [Member]        
Subsequent Event [Line Items]        
Class of warrant, outstanding 2,954