The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete. | |||||||||||||||||
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UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 13F FORM 13F INFORMATION TABLE |
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| COLUMN 1 | COLUMN 2 | COLUMN 3 | COLUMN 4 | COLUMN 5 | COLUMN 6 | COLUMN 7 | COLUMN 8 | ||||
| VALUE | SHRS OR | SH/ | PUT/ | INVESTMENT | OTHER | VOTING AUTHORITY | |||||
| NAME OF ISSUER | TITLE OF CLASS | CUSIP | (x$1000) | PRN AMT | PRN | CALL | DISCRETION | MANAGER | SOLE | SHARED | NONE |
| Argos Therapeutics Inc. | Common | 040221103 | 136 | 826,153 | SH | DFND | 1 | 0 | 826,153 | 0 | |
| Argos Therapeutics Inc. | Common | 040221103 | 42 | 256,030 | SH | Call | DFND | 1 | 0 | 256,030 | 0 |
| Proteon Therapeutics Inc. | Common | 74371L109 | 3,939 | 1,607,807 | SH | DFND | 1 | 0 | 1,607,807 | 0 | |
| Protagonist Therapeutics, Inc. | Common | 74366E102 | 5,044 | 750,632 | SH | DFND | 1 | 0 | 750,632 | 0 | |
| Jounce Therapeutics, Inc. | Common | 481116101 | 4,328 | 565,063 | SH | DFND | 1 | 0 | 565,063 | 0 | |
| Allena Pharmaceuticals | Common | 018119107 | 11,442 | 878,131 | SH | DFND | 1 | 0 | 878,131 | 0 | |