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Net Loss Per Share - Summary of Anti-Dilutive Common Stock Equivalents Outstanding (Detail) - shares
3 Months Ended 6 Months Ended
Jun. 30, 2018
Jun. 30, 2017
Jun. 30, 2018
Jun. 30, 2017
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]        
Anti-dilutive common stock equivalents 6,229,126 5,352,918 6,229,126 5,352,918
Stock Options [Member]        
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]        
Anti-dilutive common stock equivalents 6,207,172 5,313,821 6,207,172 5,313,821
Restricted Stock Units [Member]        
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]        
Anti-dilutive common stock equivalents 13,950 30,400 13,950 30,400
Employee Stock Purchase Plan [Member]        
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]        
Anti-dilutive common stock equivalents 8,004 8,697 8,004 8,697