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Condensed Consolidated Statements of Changes in Stockholders' Equity (Unaudited) - USD ($)
$ in Thousands
Total
Common Stock [Member]
Treasury Stock [Member]
Additional Paid-in Capital [Member]
Accumulated Other Comprehensive Loss [Member]
Accumulated Deficit [Member]
Balances at Dec. 31, 2021 $ 1,729,031 $ 6 $ (400) $ 3,227,471 $ (2,660) $ (1,495,386)
Balances, Shares at Dec. 31, 2021   58,937,050 3,033      
Issuance of common stock from exercises of stock options, Amount 646     646    
Issuance of common stock from exercises of stock options, Shares   105,474        
Issuance of common stock under the employee stock purchase plan 1,153     1,153    
Issuance of common stock under the employee stock purchase plan, Shares   23,625        
Stock-based compensation expense 18,268     18,268    
Change in unrealized loss on available-for-sale securities (8,541)       (8,541)  
Net loss (122,055)         (122,055)
Balances at Mar. 31, 2022 1,618,502 $ 6 $ (400) 3,247,538 (11,201) (1,617,441)
Balance, Shares at Mar. 31, 2022   59,066,149 3,033      
Balances at Dec. 31, 2021 1,729,031 $ 6 $ (400) 3,227,471 (2,660) (1,495,386)
Balances, Shares at Dec. 31, 2021   58,937,050 3,033      
Net loss (385,638)          
Balances at Sep. 30, 2022 1,380,122 $ 6 $ (400) 3,276,423 (14,883) (1,881,024)
Balance, Shares at Sep. 30, 2022   59,493,704 3,033      
Balances at Mar. 31, 2022 1,618,502 $ 6 $ (400) 3,247,538 (11,201) (1,617,441)
Balances, Shares at Mar. 31, 2022   59,066,149 3,033      
Issuance of common stock from exercises of stock options, Amount 37     37    
Issuance of common stock from exercises of stock options, Shares   31,801        
Stock-based compensation expense 14,652     14,652    
Change in unrealized loss on available-for-sale securities (2,671)       (2,671)  
Vesting of restricted stock units, net of employee tax obligations (24)     (24)    
Vesting of restricted stock units, net of employee tax obligations, Shares   290,779        
Net loss (126,260)         (126,260)
Balances at Jun. 30, 2022 1,504,236 $ 6 $ (400) 3,262,203 (13,872) (1,743,701)
Balance, Shares at Jun. 30, 2022   59,388,729 3,033      
Issuance of common stock from exercises of stock options, Amount 320     320    
Issuance of common stock from exercises of stock options, Shares   11,808        
Issuance of common stock under the employee stock purchase plan 1,193     1,193    
Issuance of common stock under the employee stock purchase plan, Shares   33,614        
Stock-based compensation expense 12,722     12,722    
Change in unrealized loss on available-for-sale securities (1,011)       (1,011)  
Vesting of restricted stock units, net of employee tax obligations (15)     (15)    
Vesting of restricted stock units, net of employee tax obligations, Shares   59,553        
Net loss (137,323)         (137,323)
Balances at Sep. 30, 2022 1,380,122 $ 6 $ (400) 3,276,423 (14,883) (1,881,024)
Balance, Shares at Sep. 30, 2022   59,493,704 3,033      
Balances at Dec. 31, 2022 1,252,599 $ 6 $ (400) 3,291,369 (10,206) (2,028,170)
Balances, Shares at Dec. 31, 2022   59,509,125 3,033      
Issuance of common stock from exercises of stock options, Amount 438     438    
Issuance of common stock from exercises of stock options, Shares   52,058        
Issuance of common stock under the employee stock purchase plan 2,863     2,863    
Issuance of common stock under the employee stock purchase plan, Shares   76,105        
Stock-based compensation expense 19,568     19,568    
Change in unrealized loss on available-for-sale securities 5,118       5,118  
Vesting of restricted stock units, net of employee tax obligations (629)     (629)    
Vesting of restricted stock units, net of employee tax obligations, Shares   124,713        
Net loss (146,828)         (146,828)
Balances at Mar. 31, 2023 (1,133,129) $ 6 $ (400) 3,313,609 (5,088) (2,174,998)
Balance, Shares at Mar. 31, 2023   59,762,001 3,033      
Balances at Dec. 31, 2022 1,252,599 $ 6 $ (400) 3,291,369 (10,206) (2,028,170)
Balances, Shares at Dec. 31, 2022   59,509,125 3,033      
Net loss (508,783)          
Balances at Sep. 30, 2023 816,659 $ 6 $ (400) 3,357,741 (3,735) (2,536,953)
Balance, Shares at Sep. 30, 2023   59,967,516 3,033      
Balances at Mar. 31, 2023 (1,133,129) $ 6 $ (400) 3,313,609 (5,088) (2,174,998)
Balances, Shares at Mar. 31, 2023   59,762,001 3,033      
Issuance of common stock from exercises of stock options, Amount 855     855    
Issuance of common stock from exercises of stock options, Shares   20,032        
Stock-based compensation expense 11,281     11,281    
Change in unrealized loss on available-for-sale securities (556)       (556)  
Vesting of restricted stock units, net of employee tax obligations (8)     (8)    
Vesting of restricted stock units, net of employee tax obligations, Shares   13,972        
Net loss (160,325)         (160,325)
Balances at Jun. 30, 2023 984,376 $ 6 $ (400) 3,325,737 (5,644) (2,335,323)
Balance, Shares at Jun. 30, 2023   59,796,005 3,033      
Issuance of common stock under the employee stock purchase plan 3,656     3,656    
Issuance of common stock under the employee stock purchase plan, Shares   87,938        
Stock-based compensation expense 28,352     28,352    
Change in unrealized loss on available-for-sale securities 1,909       1,909  
Vesting of restricted stock units, net of employee tax obligations (4)     (4)    
Vesting of restricted stock units, net of employee tax obligations, Shares   83,573        
Net loss (201,630)         (201,630)
Balances at Sep. 30, 2023 $ 816,659 $ 6 $ (400) $ 3,357,741 $ (3,735) $ (2,536,953)
Balance, Shares at Sep. 30, 2023   59,967,516 3,033