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Stock-Based Compensation - Additional Information (Detail)
1 Months Ended 3 Months Ended 6 Months Ended 9 Months Ended 12 Months Ended
Jun. 15, 2023
shares
Jan. 01, 2023
shares
Sep. 30, 2022
Sep. 30, 2023
USD ($)
Milestone
shares
Jun. 30, 2023
USD ($)
shares
Mar. 31, 2023
USD ($)
Milestone
shares
Sep. 30, 2022
USD ($)
shares
Jun. 30, 2022
USD ($)
shares
Mar. 31, 2022
shares
Jun. 30, 2023
USD ($)
Milestone
Sep. 30, 2023
USD ($)
$ / shares
shares
Sep. 30, 2022
USD ($)
Milestone
$ / shares
shares
Dec. 31, 2022
shares
Dec. 31, 2021
USD ($)
shares
Dec. 31, 2020
shares
Jun. 16, 2022
shares
Sep. 20, 2018
shares
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                                  
Share based compensation granted under plan vested period                     4 years            
Share based compensation, vest period                     1 year            
Share based compensation, term of plan                     10 years            
Total number of shares outstanding       11,420,766             11,420,766            
Common stock available for issuance under stock option plan       7,283,210             7,283,210            
Restricted stock units granted                     2,594,486            
Stock-based compensation expense | $       $ 28,691,000     $ 13,169,000       $ 60,422,000 $ 46,358,000          
Outstanding and unvested restricted stock units       3,288,804             3,288,804   1,415,481        
Total unrecognized stock-based compensation expense | $       $ 48,900,000             $ 48,900,000            
Weighted average grant date fair value per share | $ / shares                     $ 30.27 $ 25.96          
Time Based Restricted Stock Units [Member]                                  
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                                  
Share based compensation granted under plan vested period           4 years               4 years 2 years    
Share based compensation remaining vesting period           3 years               3 years      
Share based compensation vesting frequency                           quarterly      
Restricted stock units granted       1,382,300 0 330,617           0   268,119 550,890    
Restricted stock units vesting period month and year       2025-02                          
Restricted stock units vested       12,385     59,950 291,505 0   40,962     113,941      
Fair value of restricted stock units vested | $       $ 200,000     $ 2,300,000 $ 9,500,000     $ 1,600,000     $ 8,800,000      
Outstanding and unvested restricted stock units       1,721,304             1,721,304            
Total unrecognized stock-based compensation expense | $       $ 42,000,000             $ 42,000,000            
Performance Restricted Stock Units [Member]                                  
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                                  
Restricted stock units granted       19,248     57,480       881,569 569,410          
Fair value of restricted stock units vested | $         $ 0             $ 0          
Stock-based compensation expense | $       $ 2,700,000                          
Outstanding and unvested restricted stock units       1,567,500             1,567,500            
Total unrecognized stock-based compensation expense | $       $ 71,600,000             $ 71,600,000            
Stock Options [Member]                                  
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                                  
Options granted                     919,751            
Total number of shares outstanding       8,131,962             8,131,962   7,788,350        
Stock-based compensation expense | $       $ 20,251,000     $ 11,992,000       $ 39,929,000 40,659,000          
Weighted average period of unrecognized compensation costs                     2 years 9 months            
Intrinsic value of options exercised | $                     $ 1,900,000 4,400,000          
Performance-Based Stock Options [Member]                                  
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                                  
Stock-based compensation expense | $                   $ 0 $ 0 $ 0          
Performance Shares [Member]                                  
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                                  
Options granted                     0 0          
Total unrecognized stock-based compensation expense | $       $ 24,900,000             $ 24,900,000            
Number of shares outstanding and unvested stock options       455,000             455,000            
Restricted Stock Units [Member]                                  
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                                  
Stock-based compensation expense | $       $ 8,101,000     $ 730,000       $ 19,272,000 $ 4,982,000          
Restricted Stock Units Vest One Year Anniversary [Member]                                  
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                                  
Restricted stock units vesting percentage                     25.00%            
Restricted Stock Units Vest One Year Anniversary [Member] | Time Based Restricted Stock Units [Member]                                  
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                                  
Restricted stock units vesting percentage     25.00%     25.00%                 25.00%    
Restricted stock units vesting period month and year                             2021-04    
Restricted Stock Units Vest Two Year Anniversary [Member] | Time Based Restricted Stock Units [Member]                                  
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                                  
Restricted stock units vesting percentage           75.00%               75.00% 75.00%    
Restricted stock units vesting period month and year                             2022-04    
2011 Plan [Member]                                  
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                                  
Options granted                     0            
2014 Plan [Member]                                  
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                                  
Common stock shares annual increase added to plan   2,380,365                              
2014 Plan [Member] | Performance Restricted Stock Units [Member]                                  
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                                  
Fair value of restricted stock units vested | $       2,600,000   $ 5,500,000                      
Stock-based compensation expense | $       $ 2,900,000   $ 8,500,000                      
Regulatory development Milestone achieved | Milestone       1   1                      
Number of commercial milestone not met | Milestone       1                          
2014 Plan [Member] | Performance Restricted Stock Units [Member] | Milestone One [Member]                                  
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                                  
Milestone performance restricted stock percentage           0.27                      
2014 Plan [Member] | Performance-Based Stock Options [Member]                                  
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                                  
Milestone performance-based stock option grants percentage                           30.00%      
Stock-based compensation expense | $       $ 10,700,000                          
Regulatory development Milestone achieved | Milestone       1           0   0          
2014 Plan [Member] | Maximum [Member]                                  
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                                  
Percentage of increase on outstanding shares of Common stock                         4.00%        
2016 Plan [Member]                                  
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                                  
Total number of shares reserved for issuance                                 1,200,000
2014 Employee Stock Purchase Plan [Member]                                  
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                                  
Additional number of shares reserved for issuance 500,000                                
Total number of shares reserved for issuance 1,082,000                             300,000