Product Revenue Reserves and Allowances - Concentration Risk (Details)	12 Months Ended
	Dec. 31, 2022	Dec. 31, 2021
Revenue from Contract with Customer Benchmark | Customer Concentration Risk | Largest Customers, Largest Customer
Concentration Risk
Concentration risk (as a percent)	53.00%	55.00%
Revenue from Contract with Customer Benchmark | Customer Concentration Risk | Largest Customers, Second-largest Customer
Concentration Risk
Concentration risk (as a percent)	13.00%	8.00%
Revenue from Contract with Customer Benchmark | Customer Concentration Risk | Largest Customers, Third-largest Customer
Concentration Risk
Concentration risk (as a percent)	11.00%	9.00%
Accounts Receivable, Net | Credit Concentration Risk | Largest Customers, Largest Customer
Concentration Risk
Concentration risk (as a percent)	40.00%	45.00%
Accounts Receivable, Net | Credit Concentration Risk | Largest Customers, Second-largest Customer
Concentration Risk
Concentration risk (as a percent)	18.00%	13.00%
Accounts Receivable, Net | Credit Concentration Risk | Largest Customers, Third-largest Customer
Concentration Risk
Concentration risk (as a percent)	15.00%	12.00%