Net Income Per Share (Tables)

12 Months Ended

Dec. 31, 2021

Table Text Blocks

Schedule of net income (loss) and the number of shares used to compute basic and diluted net income (loss) per share

	Year Ended December 31,
	2021		2020		2019
Net income (loss) - basic and diluted	$	(644,085)	$	313,882	$	(347,694)
Weighted average shares outstanding - basic		58,518		54,534		47,829
Effect of dilutive securities:
Stock options		—		1,303		—
Restricted stock units		—		331		—
Weighted average shares outstanding - diluted		58,518		56,168		47,829
Net income (loss) per share - basic	$	(11.01)	$	5.76	$	(7.27)
Net income (loss) per share - diluted		(11.01)		5.59		(7.27)

Schedule of common stock equivalents excluded from calculation of diluted net loss per share applicable to common stockholders

	Year Ended December 31,
	2021	2020	2019
Stock options	5,682	4,480	5,796
Restricted stock units	1,590	13	420
ESPP shares	24	19	14
Total	7,296	4,512	6,230