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Condensed Consolidated Statements of Stockholders' Equity - USD ($)
$ in Thousands
Common Stock
Additional Paid-In Capital
Accumulated Other Comprehensive Loss
Accumulated Deficit
Total
Beginning Balance at Dec. 31, 2018 $ 44 $ 1,016,690 $ (180) $ (597,545) $ 419,009
Beginning Balance (in shares) at Dec. 31, 2018 44,037,026,000        
Increase (Decrease) in Stockholders' Equity          
Issuance of common stock under stock plan   2,061     2,061
Issuance of common stock under stock plan (in shares) 134,439,000        
Stock-based compensation expense   10,295     10,295
Unrealized gain (loss) on available-for-sale securities     270   270
Cumulative translation adjustment     (15)   (15)
Net income (loss)       (87,407) (87,407)
Ending Balance at Mar. 31, 2019 $ 44 1,029,046 75 (684,952) 344,213
Ending Balance (in shares) at Mar. 31, 2019 44,171,465,000        
Beginning Balance at Dec. 31, 2018 $ 44 1,016,690 (180) (597,545) $ 419,009
Beginning Balance (in shares) at Dec. 31, 2018 44,037,026,000        
Increase (Decrease) in Stockholders' Equity          
Purchase of common stock under ESPP (in shares)         10,718
Cumulative translation adjustment         $ (10)
Net income (loss)         (281,363)
Ending Balance at Sep. 30, 2019 $ 49 1,394,566 637 (878,908) 516,344
Ending Balance (in shares) at Sep. 30, 2019 49,175,442,000        
Beginning Balance at Mar. 31, 2019 $ 44 1,029,046 75 (684,952) 344,213
Beginning Balance (in shares) at Mar. 31, 2019 44,171,465,000        
Increase (Decrease) in Stockholders' Equity          
Issuance of common stock under stock plan   5,813     5,813
Issuance of common stock under stock plan (in shares) 215,299,000        
Purchase of common stock under ESPP   522     522
Purchase of common stock under ESPP (in shares) 10,718,000        
Stock-based compensation expense   13,666     13,666
Issuance of common stock $ 5 327,437     327,442
Issuance of common stock (in shares) 4,662,162,000        
Unrealized gain (loss) on available-for-sale securities     845   845
Cumulative translation adjustment     7   7
Net income (loss)       (99,681) (99,681)
Ending Balance at Jun. 30, 2019 $ 49 1,376,484 927 (784,633) 592,827
Ending Balance (in shares) at Jun. 30, 2019 49,059,644,000        
Increase (Decrease) in Stockholders' Equity          
Issuance of common stock under stock plan   3,089     3,089
Issuance of common stock under stock plan (in shares) 115,798,000        
Stock-based compensation expense   14,993     14,993
Unrealized gain (loss) on available-for-sale securities     (287)   (287)
Cumulative translation adjustment     (3)   (3)
Net income (loss)       (94,275) (94,275)
Ending Balance at Sep. 30, 2019 $ 49 1,394,566 637 (878,908) 516,344
Ending Balance (in shares) at Sep. 30, 2019 49,175,442,000        
Beginning Balance at Dec. 31, 2019 $ 49 1,412,083 (2,535) (945,238) $ 464,359
Beginning Balance (in shares) at Dec. 31, 2019 49,272,223,000       49,272,223
Increase (Decrease) in Stockholders' Equity          
Issuance of common stock under stock plan $ 1 1,612     $ 1,613
Issuance of common stock under stock plan (in shares) 186,166,000        
Stock-based compensation expense   17,026     17,026
Issuance of common stock $ 4 308,419     308,423
Issuance of common stock (in shares) 4,710,144,000        
Unrealized gain (loss) on available-for-sale securities     2,492   2,492
Cumulative translation adjustment     (26)   (26)
Net income (loss)       (110,954) (110,954)
Ending Balance at Mar. 31, 2020 $ 54 1,739,140 (69) (1,056,192) 682,933
Ending Balance (in shares) at Mar. 31, 2020 54,168,533,000        
Beginning Balance at Dec. 31, 2019 $ 49 1,412,083 (2,535) (945,238) $ 464,359
Beginning Balance (in shares) at Dec. 31, 2019 49,272,223,000       49,272,223
Increase (Decrease) in Stockholders' Equity          
Purchase of common stock under ESPP (in shares)         17,018
Cumulative translation adjustment         $ (64)
Net income (loss)         399,550
Ending Balance at Sep. 30, 2020 $ 56 1,867,572 (1,940) (545,688) $ 1,320,000
Ending Balance (in shares) at Sep. 30, 2020 55,514,395,000       55,514,395
Beginning Balance at Mar. 31, 2020 $ 54 1,739,140 (69) (1,056,192) $ 682,933
Beginning Balance (in shares) at Mar. 31, 2020 54,168,533,000        
Increase (Decrease) in Stockholders' Equity          
Issuance of common stock under stock plan   2,335     2,335
Issuance of common stock under stock plan (in shares) 98,950,000        
Purchase of common stock under ESPP   942     942
Purchase of common stock under ESPP (in shares) 17,018,000        
Stock-based compensation expense   19,675     19,675
Unrealized gain (loss) on available-for-sale securities     (1,057)   (1,057)
Cumulative translation adjustment     6   6
Net income (loss)       (123,474) (123,474)
Other   7     7
Ending Balance at Jun. 30, 2020 $ 54 1,762,099 (1,120) (1,179,666) 581,367
Ending Balance (in shares) at Jun. 30, 2020 54,284,501,000        
Increase (Decrease) in Stockholders' Equity          
Issuance of common stock under stock plan $ 1 6,279     6,280
Issuance of common stock under stock plan (in shares) 194,375,000        
Stock-based compensation expense   19,889     19,889
Issuance of common stock $ 1 79,305     79,306
Issuance of common stock (in shares) 1,035,519,000        
Unrealized gain (loss) on available-for-sale securities     (777)   (777)
Cumulative translation adjustment     (43)   (43)
Net income (loss)       633,978 633,978
Ending Balance at Sep. 30, 2020 $ 56 $ 1,867,572 $ (1,940) $ (545,688) $ 1,320,000
Ending Balance (in shares) at Sep. 30, 2020 55,514,395,000       55,514,395