0001493152-22-032068.txt : 20221114 0001493152-22-032068.hdr.sgml : 20221114 20221114162003 ACCESSION NUMBER: 0001493152-22-032068 CONFORMED SUBMISSION TYPE: 13F-HR PUBLIC DOCUMENT COUNT: 2 CONFORMED PERIOD OF REPORT: 20220930 FILED AS OF DATE: 20221114 DATE AS OF CHANGE: 20221114 EFFECTIVENESS DATE: 20221114 FILER: COMPANY DATA: COMPANY CONFORMED NAME: Opaleye Management Inc. CENTRAL INDEX KEY: 0001595855 IRS NUMBER: 205648796 STATE OF INCORPORATION: MA FISCAL YEAR END: 1231 FILING VALUES: FORM TYPE: 13F-HR SEC ACT: 1934 Act SEC FILE NUMBER: 028-15896 FILM NUMBER: 221385774 BUSINESS ADDRESS: STREET 1: ONE BOSTON PLACE STREET 2: SUITE 2600 CITY: BOSTON STATE: MA ZIP: 02108 BUSINESS PHONE: 617-904-9195 MAIL ADDRESS: STREET 1: ONE BOSTON PLACE STREET 2: SUITE 2600 CITY: BOSTON STATE: MA ZIP: 02108 13F-HR 1 primary_doc.xml 13F-HR LIVE false true false 0001595855 XXXXXXXX 09-30-2022 09-30-2022 false Opaleye Management Inc.
One Boston Place Suite 2600 Boston MA 02108
13F HOLDINGS REPORT 028-15896 N
James Silverman President 617-229-5085 /s/ James Silverman Boston MA 11-14-2022 0 42 242133
INFORMATION TABLE 2 infotable.xml 4D MOLECULAR THERAPEUTICS INC COM 35104E100 2820 350700 SH SOLE 350700 0 0 ALLAKOS INC COM 01671P100 939 153500 SH SOLE 153500 0 0 ASTRIA THERAPEUTICS INC COM 04635X102 1207 133500 SH SOLE 133500 0 0 BIOLINERX LTD SPONSORED ADS 09071M205 16 16667 SH SOLE 16667 0 0 CHIMERIX INC COM 16934W106 704 365000 SH SOLE 365000 0 0 CODEXIS INC COM 192005106 6999 1155000 SH SOLE 1155000 0 0 CRINETICS PHARMACEUTICALS INC COM 22663K107 13184 671300 SH SOLE 671300 0 0 CUTERA INC COM 232109108 6735 147700 SH SOLE 147700 0 0 CYTOKINETICS INC COM NEW 23282W605 12742 263000 SH SOLE 263000 0 0 EDAP TMS SA SPONSORED ADR 268311107 588 71300 SH SOLE 71300 0 0 EDGEWISE THERAPEUTICS INC COM 28036F105 6248 635000 SH SOLE 635000 0 0 ETON PHARMACEUTICALS INC COM 29772L108 5294 2521000 SH SOLE 2521000 0 0 FORTRESS BIOTECH INC COM 34960Q109 2579 2999000 SH SOLE 2999000 0 0 GRAPHITE BIO INC COM 38870X104 1830 577250 SH SOLE 577250 0 0 HARROW HEALTH INC COM 415858109 40360 3343817 SH SOLE 3343817 0 0 IDEAYA BIOSCIENCES INC COM 45166A102 22 1500 SH SOLE 1500 0 0 IMPEL PHARMACEUTICALS INC COM 45258K109 1243 255250 SH SOLE 255250 0 0 INHIBRX INC COM 45720L107 5254 292700 SH SOLE 292700 0 0 JOURNEY MEDICINE CORP COM 48115J109 638 259293 SH SOLE 259293 0 0 KEROS THERAPEUTICS INC COM 492327101 12087 321300 SH SOLE 321300 0 0 LARIMAR THERAPEUTICS INC COM 517125100 5318 1661784 SH SOLE 1661784 0 0 LIQUIDIA CORPORATION COM NEW 53635D202 3065 563500 SH SOLE 563500 0 0 LUMOS PHARMA INC COM 55028X109 412 46576 SH SOLE 46576 0 0 MEIRAGTX HLDGS PLC COM G59665102 84 10000 SH SOLE 10000 0 0 MERSANA THERAPEUTICS INC COM 59045L106 6086 900300 SH SOLE 900300 0 0 MERUS N.V. COM N5749R100 5072 253200 SH SOLE 253200 0 0 MODULAR MEDICAL INC COM NEW 60785L207 1135 275422 SH SOLE 275422 0 0 MORPHOSYS AG SPONSORED ADS 617760202 609 121015 SH SOLE 121015 0 0 NEOLEUKIN THERAPEUTICS INC COM 64049K104 368 575000 SH SOLE 575000 0 0 NEUROPACE INC COM 641288105 436 116324 SH SOLE 116324 0 0 OCULAR THERAPEUTIX INC COM 67576A100 26830 6465000 SH SOLE 6465000 0 0 OPTINOSE INC COM 68404V100 333 90970 SH SOLE 90970 0 0 PROQR THERAPEUTICS NV SHS EURO N71542109 2318 3115000 SH SOLE 3115000 0 0 PROTARA THERAPEUTICS INC COM STK 74365U107 7993 2708067 SH SOLE 2708067 0 0 RHYTHM PHARMACEUTICALS INC COM 76243J105 19845 810000 SH SOLE 810000 0 0 STEREOTAXIS INC COM NEW 85916J409 2802 1556800 SH SOLE 1556800 0 0 TELA BIO INC COM 872381108 17351 2036551 SH SOLE 2036551 0 0 THESEUS PHARMACEUTICALS INC COM 88369M101 1280 220650 SH SOLE 32300 0 0 TRACON PHARMACEUTICALS INC COM NEW 89237H209 6997 4190000 SH SOLE 4190000 0 0 UROGEN PHARMA LTD COM M96088105 3307 397500 SH SOLE 397500 0 0 VAXCYTE INC COM 92243G108 4560 190000 SH SOLE 190000 0 0 XOMA CORP DEL COM NEW 98419J206 4442 248000 SH SOLE 248000 0 0