0001420506-24-000335.txt : 20240214 0001420506-24-000335.hdr.sgml : 20240214 20240214081317 ACCESSION NUMBER: 0001420506-24-000335 CONFORMED SUBMISSION TYPE: 13F-HR PUBLIC DOCUMENT COUNT: 2 CONFORMED PERIOD OF REPORT: 20231231 FILED AS OF DATE: 20240214 DATE AS OF CHANGE: 20240214 EFFECTIVENESS DATE: 20240214 FILER: COMPANY DATA: COMPANY CONFORMED NAME: Ghost Tree Capital, LLC CENTRAL INDEX KEY: 0001595851 ORGANIZATION NAME: IRS NUMBER: 462174699 STATE OF INCORPORATION: DE FISCAL YEAR END: 1231 FILING VALUES: FORM TYPE: 13F-HR SEC ACT: 1934 Act SEC FILE NUMBER: 028-16059 FILM NUMBER: 24632507 BUSINESS ADDRESS: STREET 1: 667 MADISON AVENUE STREET 2: 5TH FLOOR, SUITE 12 CITY: NEW YORK STATE: NY ZIP: 10065 BUSINESS PHONE: 6467790120 MAIL ADDRESS: STREET 1: 667 MADISON AVENUE STREET 2: 5TH FLOOR, SUITE 12 CITY: NEW YORK STATE: NY ZIP: 10065 13F-HR 1 primary_doc.xml X0202 13F-HR LIVE false true false 0001595851 XXXXXXXX 12-31-2023 12-31-2023 false Ghost Tree Capital, LLC

667 MADISON AVENUE 5TH FLOOR, SUITE 12 NEW YORK NY 10065

13F HOLDINGS REPORT 028-16059 N MATTHEW JAMES DIAZ 6467790121 MATTHEW JAMES DIAZ, CHIEF COMPLIANCE OFFICER NEW YORK NY 02-14-2024 0 52 305864042 false INFORMATION TABLE 2 Form13F_InfoTable.xml INFORMATION TABLE FOR GHOST TREE CAPITAL, LLC (7119) ACADIA PHARMACEUTICALS INC COM 004225108 1565500 50000 SH SOLE 50000 0 0 AEROVATE THERAPEUTICS INC COM 008064107 4752300 210000 SH SOLE 210000 0 0 ALNYLAM PHARMACEUTICALS INC COM 02043Q107 5263775 27500 SH SOLE 27500 0 0 AMBRX BIOPHARMA INC COM 641871108 6764000 475000 SH SOLE 475000 0 0 AMYLYX PHARMACEUTICALS INC COM 03237H101 2944000 200000 SH Call SOLE 200000 0 0 APELLIS PHARMACEUTICALS INC COM 03753U106 5986000 100000 SH Call SOLE 100000 0 0 ARGENX SE SPONSORED ADR 04016X101 5706450 15000 SH SOLE 15000 0 0 ARVINAS INC COM 04335A105 2438730 59250 SH SOLE 59250 0 0 ASCENDIS PHARMA A/S SPONSORED ADR 04351P101 2519000 20000 SH SOLE 20000 0 0 ASTRIA THERAPEUTICS INC COM 04635X102 2572800 335000 SH SOLE 335000 0 0 AXSOME THERAPEUTICS INC COM 05464T104 13132350 165000 SH SOLE 165000 0 0 BIOHAVEN LTD COM G1110E107 11770000 275000 SH SOLE 275000 0 0 BLUEBIRD BIO INC COM 09609G100 641700 465000 SH SOLE 465000 0 0 BRIDGEBIO PHARMA INC COM 10806X102 5046250 125000 SH SOLE 125000 0 0 CABALETTA BIO INC COM 12674W109 3405000 150000 SH SOLE 150000 0 0 COGENT BIOSCIENCES INC COM 19240Q201 1146600 195000 SH SOLE 195000 0 0 CRINETICS PHARMACEUTICALS IN COM 22663K107 2312700 65000 SH SOLE 65000 0 0 CYMABAY THERAPEUTICS INC COM 23257D103 2125800 90000 SH SOLE 90000 0 0 CYTOKINETICS INC COM NEW 23282W605 834900 10000 SH SOLE 10000 0 0 CYTOKINETICS INC COM NEW 23282W605 6679200 80000 SH Call SOLE 80000 0 0 DECIPHERA PHARMACEUTICALS IN COM 24344T101 3629250 225000 SH SOLE 225000 0 0 EYEPOINT PHARMACEUTICALS INC COM NEW 30233G209 3813150 165000 SH SOLE 165000 0 0 INHIBRX INC COM 45720L107 1330000 35000 SH SOLE 35000 0 0 ISHARES TR RUSSELL 2000 ETF 464287655 50177500 250000 SH Call SOLE 250000 0 0 KALVISTA PHARMACEUTICALS INC COM 483497103 1592941 130036 SH SOLE 130036 0 0 KRYSTAL BIOTECH INC COM 501147102 6203000 50000 SH SOLE 50000 0 0 MADRIGAL PHARMACEUTICALS INC COM 558868105 3470700 15000 SH SOLE 15000 0 0 MARINUS PHARMACEUTICALS INC COM NEW 56854Q200 1467450 135000 SH SOLE 135000 0 0 MOONLAKE IMMUNOTHERAPEUTICS CLASS A ORD 61559X104 4831200 80000 SH SOLE 80000 0 0 MOONLAKE IMMUNOTHERAPEUTICS CLASS A ORD 61559X104 15097500 250000 SH Call SOLE 250000 0 0 NATERA INC COM 632307104 2192400 35000 SH SOLE 35000 0 0 PERSPECTIVE THERAPEUTICS INC COM 46489V104 643200 1600000 SH SOLE 1600000 0 0 PHATHOM PHARMACEUTICALS INC COM 71722W107 3517250 385241 SH SOLE 385241 0 0 PMV PHARMACEUTICALS INC COM 69353Y103 2247500 725000 SH SOLE 725000 0 0 PROTAGONIST THERAPEUTICS INC COM 74366E102 2866250 125000 SH SOLE 125000 0 0 REPLIMUNE GROUP INC COM 76029N106 3372000 400000 SH SOLE 400000 0 0 REVANCE THERAPEUTICS INC COM 761330109 3296250 375000 SH SOLE 375000 0 0 REVOLUTION MEDICINES INC COM 76155X100 2151000 75000 SH Put SOLE 75000 0 0 ROIVANT SCIENCES LTD SHS G76279101 6738000 600000 SH SOLE 600000 0 0 SAREPTA THERAPEUTICS INC COM 803607100 9643000 100000 SH SOLE 100000 0 0 SAVARA INC COM 805111101 3525000 750000 SH SOLE 750000 0 0 SOLENO THERAPEUTICS INC COM 834203309 4523496 112385 SH SOLE 112385 0 0 SPDR SER TR S&P BIOTECH 78464A870 22322500 250000 SH Call SOLE 250000 0 0 SPDR SER TR S&P BIOTECH 78464A870 26787000 300000 SH Put SOLE 300000 0 0 STRUCTURE THERAPEUTICS INC SPONSORED ADS 86366E106 6114000 150000 SH SOLE 150000 0 0 TARSUS PHARMACEUTICALS INC COM 87650L103 6075000 300000 SH SOLE 300000 0 0 TAYSHA GENE THERAPIES INC COM SHS 877619106 3717000 2100000 SH SOLE 2100000 0 0 TG THERAPEUTICS INC COM 88322Q108 4270000 250000 SH SOLE 250000 0 0 UNIQURE NV SHS N90064101 1117050 165000 SH SOLE 165000 0 0 VAXCYTE INC COM 92243G108 4396000 70000 SH SOLE 70000 0 0 VERONA PHARMA PLC SPONSORED ADS 925050106 596400 30000 SH SOLE 30000 0 0 VIRIDIAN THERAPEUTICS INC COM 92790C104 6534000 300000 SH SOLE 300000 0 0