0001420506-23-001046.txt : 20230515 0001420506-23-001046.hdr.sgml : 20230515 20230515084206 ACCESSION NUMBER: 0001420506-23-001046 CONFORMED SUBMISSION TYPE: 13F-HR PUBLIC DOCUMENT COUNT: 2 CONFORMED PERIOD OF REPORT: 20230331 FILED AS OF DATE: 20230515 DATE AS OF CHANGE: 20230515 EFFECTIVENESS DATE: 20230515 FILER: COMPANY DATA: COMPANY CONFORMED NAME: Ghost Tree Capital, LLC CENTRAL INDEX KEY: 0001595851 IRS NUMBER: 462174699 STATE OF INCORPORATION: DE FISCAL YEAR END: 1231 FILING VALUES: FORM TYPE: 13F-HR SEC ACT: 1934 Act SEC FILE NUMBER: 028-16059 FILM NUMBER: 23918691 BUSINESS ADDRESS: STREET 1: 667 MADISON AVENUE STREET 2: 5TH FLOOR, SUITE 12 CITY: NEW YORK STATE: NY ZIP: 10065 BUSINESS PHONE: 6467790120 MAIL ADDRESS: STREET 1: 667 MADISON AVENUE STREET 2: 5TH FLOOR, SUITE 12 CITY: NEW YORK STATE: NY ZIP: 10065 13F-HR 1 primary_doc.xml X0202 13F-HR LIVE false true false 0001595851 XXXXXXXX 03-31-2023 03-31-2023 false Ghost Tree Capital, LLC

667 MADISON AVENUE 5TH FLOOR, SUITE 12 NEW YORK NY 10065

13F HOLDINGS REPORT 028-16059 N MATTHEW JAMES DIAZ 6467790121 MATTHEW JAMES DIAZ, CHIEF COMPLIANCE OFFICER NEW YORK NY 05-15-2023 0 58 338325000 false INFORMATION TABLE 2 Form13F_InfoTable.xml INFORMATION TABLE FOR GHOST TREE CAPITAL, LLC (5997) 89BIO INC COM 282559103 1523000 100000 SH Call SOLE 100000 0 0 89BIO INC COM 282559103 3046000 200000 SH SOLE 200000 0 0 AADI BIOSCIENCE INC COM 00032Q104 1086000 150000 SH SOLE 150000 0 0 ACLARIS THERAPEUTICS INC COM 00461U105 3438000 425000 SH SOLE 425000 0 0 AEROVATE THERAPEUTICS INC COM 008064107 4034000 200000 SH SOLE 200000 0 0 AKERO THERAPEUTICS INC COM 00973Y108 10522000 275000 SH SOLE 275000 0 0 ALPINE IMMUNE SCIENCES INC COM 02083G100 1544000 200000 SH SOLE 200000 0 0 ALTIMMUNE INC COM NEW 02155H200 1688000 400000 SH Call SOLE 400000 0 0 AMBRX BIOPHARMA INC SPONSORED ADS 02290A102 2230000 250000 SH SOLE 250000 0 0 AMICUS THERAPEUTICS INC COM 03152W109 5268000 475000 SH SOLE 475000 0 0 AMYLYX PHARMACEUTICALS INC COM 03237H101 13937000 475000 SH SOLE 475000 0 0 APELLIS PHARMACEUTICALS INC COM 03753U106 10858000 164620 SH SOLE 164620 0 0 APELLIS PHARMACEUTICALS INC COM 03753U106 3423000 51900 SH Call SOLE 51900 0 0 ARCUS BIOSCIENCES INC COM 03969F109 1368000 75000 SH SOLE 75000 0 0 ASCENDIS PHARMA A/S SPONSORED ADR 04351P101 11794000 110000 SH SOLE 110000 0 0 ASTRIA THERAPEUTICS INC COM 04635X102 5985000 450000 SH SOLE 450000 0 0 AVIDITY BIOSCIENCES INC COM 05370A108 1919000 125000 SH SOLE 125000 0 0 AXSOME THERAPEUTICS INC COM 05464T104 13878000 225000 SH SOLE 225000 0 0 BIOCRYST PHARMACEUTICALS INC COM 09058V103 2294000 275000 SH SOLE 275000 0 0 BIOMEA FUSION INC COM 09077A106 3721000 120000 SH SOLE 120000 0 0 BRIDGEBIO PHARMA INC COM 10806X102 415000 25000 SH SOLE 25000 0 0 COGENT BIOSCIENCES INC COM 19240Q201 5935000 550000 SH SOLE 550000 0 0 CTI BIOPHARMA CORP COM 12648L601 8400000 2000000 SH SOLE 2000000 0 0 DISC MEDICINE INC COM 254604101 2119000 100000 SH SOLE 100000 0 0 FIBROGEN INC COM 31572Q808 494000 26500 SH SOLE 26500 0 0 FUSION PHARMACEUTICALS INC COM 36118A100 1320000 350000 SH SOLE 350000 0 0 GERON CORP COM 374163103 977000 450000 SH SOLE 450000 0 0 IMMUNOGEN INC COM 45253H101 480000 124977 SH SOLE 124977 0 0 INCYTE CORP COM 45337C102 5420000 75000 SH SOLE 75000 0 0 IOVANCE BIOTHERAPEUTICS INC COM 462260100 6110000 1000000 SH SOLE 1000000 0 0 IVERIC BIO INC COM 46583P102 4258000 175000 SH SOLE 175000 0 0 JOHNSON & JOHNSON COM 478160104 7750000 50000 SH SOLE 50000 0 0 KARUNA THERAPEUTICS INC COM 48576A100 3179000 17500 SH SOLE 17500 0 0 KEZAR LIFE SCIENCES INC COM 49372L100 548000 175000 SH SOLE 175000 0 0 MADRIGAL PHARMACEUTICALS INC COM 558868105 7268000 30000 SH SOLE 30000 0 0 MIRATI THERAPEUTICS INC COM 60468T105 5205000 140000 SH SOLE 140000 0 0 MOONLAKE IMMUNOTHERAPEUTICS CLASS A ORD 61559X104 4171000 195000 SH SOLE 195000 0 0 PFIZER INC COM 717081103 8160000 200000 SH SOLE 200000 0 0 PROMETHEUS BIOSCIENCES INC COM 74349U108 1610000 15000 SH SOLE 15000 0 0 PROTAGONIST THERAPEUTICS INC COM 74366E102 5175000 225000 SH SOLE 225000 0 0 RAIN ONCOLOGY INC COM 75082Q105 2185000 250000 SH SOLE 250000 0 0 REATA PHARMACEUTICALS INC CL A 75615P103 6364000 70000 SH SOLE 70000 0 0 REATA PHARMACEUTICALS INC CL A 75615P103 27276000 300000 SH Call SOLE 300000 0 0 REVANCE THERAPEUTICS INC COM 761330109 8053000 250000 SH SOLE 250000 0 0 SAREPTA THERAPEUTICS INC COM 803607100 8270000 60000 SH SOLE 60000 0 0 SAREPTA THERAPEUTICS INC COM 803607100 17229000 125000 SH Call SOLE 125000 0 0 SPDR SER TR S&P BIOTECH 78464A870 22863000 300000 SH Call SOLE 300000 0 0 SPRINGWORKS THERAPEUTICS INC COM 85205L107 710000 27578 SH SOLE 27578 0 0 SYNDAX PHARMACEUTICALS INC COM 87164F105 6864000 325000 SH SOLE 325000 0 0 TARSUS PHARMACEUTICALS INC COM 87650L103 1006000 80000 SH SOLE 80000 0 0 TG THERAPEUTICS INC COM 88322Q108 16544000 1100000 SH SOLE 1100000 0 0 UNIQURE NV SHS N90064101 7553000 375000 SH SOLE 375000 0 0 VANDA PHARMACEUTICALS INC COM 921659108 85000 12500 SH SOLE 12500 0 0 VAXCYTE INC COM 92243G108 8433000 225000 SH SOLE 225000 0 0 VIKING THERAPEUTICS INC COM 92686J106 9990000 600000 SH SOLE 600000 0 0 VIRIDIAN THERAPEUTICS INC COM 92790C104 4452000 175000 SH SOLE 175000 0 0 X4 PHARMACEUTICALS INC COM 98420X103 740000 850000 SH SOLE 850000 0 0 XENON PHARMACEUTICALS INC COM 98420N105 7158000 200000 SH SOLE 200000 0 0