The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
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COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP FIGI (to the nearest dollar) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
ACADIA HEALTHCARE COMPANY IN COM 00404A109 BBG001SNNWL7 83,475,360 1,073,500 SH   SOLE   1,073,500 0 0
ACCOLADE INC COM 00437E102 BBG00S2L1ZR1 41,854,850 3,485,000 SH   SOLE   3,485,000 0 0
ACELRX PHARMACEUTICALS INC COM NEW 00444T209 BBG001TFZCK5 232,598 316,460 SH   SOLE   316,460 0 0
ACLARIS THERAPEUTICS INC COM 00461U105 BBG003LF0QS8 3,148,420 2,998,495 SH   SOLE   2,998,495 0 0
ACUMEN PHARMACEUTICALS INC COM 00509G209 BBG0058YJ326 8,832,227 2,300,059 SH   SOLE   2,300,059 0 0
ADAPTIMMUNE THERAPEUTICS PLC SPONDS ADR 00653A107 BBG008G65WD1 1,923,396 2,425,468 SH   SOLE   2,425,468 0 0
AGILON HEALTH INC COM 00857U107 BBG00HCYVQR3 108,306,500 8,630,000 SH   SOLE   8,630,000 0 0
AGIOS PHARMACEUTICALS INC COM 00847X104 BBG001T8R687 47,928,893 2,152,173 SH   SOLE   2,152,173 0 0
AKERO THERAPEUTICS INC COM 00973Y108 BBG00L9211Z7 25,242,844 1,081,064 SH   SOLE   1,081,064 0 0
ALIGN TECHNOLOGY INC COM 016255101 BBG001SCF1B9 60,280,000 220,000 SH   SOLE   220,000 0 0
ALNYLAM PHARMACEUTICALS INC COM 02043Q107 BBG001S7FTC8 44,981,350 235,000 SH   SOLE   235,000 0 0
AMGEN INC COM 031162100 BBG001S5NNL6 21,457,490 74,500 SH   SOLE   74,500 0 0
AMICUS THERAPEUTICS INC COM 03152W109 BBG001SN96V9 15,095,407 1,063,806 SH   SOLE   1,063,806 0 0
AMYLYX PHARMACEUTICALS INC COM 03237H101 BBG00DP10YW1 7,875,377 535,012 SH   SOLE   535,012 0 0
APPLIED THERAPEUTICS INC COM 03828A101 BBG001SMJMY2 2,998,903 895,195 SH   SOLE   895,195 0 0
ARGENX SE SPONSORED ADR 04016X101 BBG00GHB88Y8 87,213,578 229,250 SH   SOLE   229,250 0 0
ASCENDIS PHARMA A/S SPONSORED ADR 04351P101 BBG007R7VP72 36,525,500 290,000 SH   SOLE   290,000 0 0
AURINIA PHARMACEUTICALS INC COM 05156V102 BBG001S68013 3,709,004 412,570 SH   SOLE   412,570 0 0
AZENTA INC COM 114340102 BBG001S8F1B8 33,058,550 507,500 SH   SOLE   507,500 0 0
BEAM THERAPEUTICS INC COM 07373V105 BBG00KXC8655 3,033,125 111,430 SH   SOLE   111,430 0 0
BIOCRYST PHARMACEUTICALS INC COM 09058V103 BBG001S7K151 19,589,582 3,270,381 SH   SOLE   3,270,381 0 0
BIOMARIN PHARMACEUTICAL INC COM 09061G101 BBG001S76R05 14,350,381 148,832 SH   SOLE   148,832 0 0
BIOMEA FUSION INC COM 09077A106 BBG00YS4WDD8 2,630,254 181,147 SH   SOLE   181,147 0 0
BLUEPRINT MEDICINES CORP COM 09627Y109 BBG001V11BV0 265,795,740 2,881,567 SH   SOLE   2,881,567 0 0
BOSTON SCIENTIFIC CORP COM 101137107 BBG001S63L94 71,250,825 1,232,500 SH   SOLE   1,232,500 0 0
CELLDEX THERAPEUTICS INC NEW COM NEW 15117B202 BBG001S7QN20 38,456,160 969,646 SH   SOLE   969,646 0 0
CEREVEL THERAPEUTICS HLDNG I COM 15678U128 BBG00VCYVLJ2 113,387,988 2,674,245 SH   SOLE   2,674,245 0 0
COLLEGIUM PHARMACEUTICAL INC COM 19459J104 BBG001T535S9 17,298,360 562,000 SH   SOLE   562,000 0 0
COMPASS THERAPEUTICS INC COM 20454B104 BBG00LPXKF34 8,601,509 5,513,788 SH   SOLE   5,513,788 0 0
COMPUGEN LTD ORD M25722105 BBG001S5PQC7 2,554,180 1,289,990 SH   SOLE   1,289,990 0 0
DEXCOM INC COM 252131107 BBG001SKZG99 73,957,640 596,000 SH   SOLE   596,000 0 0
DISC MEDICINE INC COM 254604101 BBG00W9MJL04 20,993,912 363,468 SH   SOLE   363,468 0 0
DYNAVAX TECHNOLOGIES CORP COM NEW 268158201 BBG001S7HTB7 23,423,127 1,675,474 SH   SOLE   1,675,474 0 0
EDAP TMS S A SPONSORED ADR 268311107 BBG001SB3ML7 7,320,324 1,386,425 SH   SOLE   1,386,425 0 0
EDWARDS LIFESCIENCES CORP COM 28176E108 BBG001SF2288 49,356,625 647,300 SH   SOLE   647,300 0 0
ELI LILLY & CO COM 532457108 BBG001S5STL8 40,512,940 69,500 SH   SOLE   69,500 0 0
ESSA PHARMA INC COM NEW 29668H708 BBG0080GLFK7 4,468,233 677,005 SH   SOLE   677,005 0 0
EVOLENT HEALTH INC CL A 30050B101 BBG005CHLMB3 130,798,800 3,960,000 SH   SOLE   3,960,000 0 0
EXACT SCIENCES CORP COM 30063P105 BBG001SGCLB9 75,422,610 1,019,500 SH   SOLE   1,019,500 0 0
FRESHPET INC COM 358039105 BBG001V04FM0 57,478,500 662,500 SH   SOLE   662,500 0 0
FULCRUM THERAPEUTICS INC COM 359616109 BBG00DDY1RM7 4,911,793 727,673 SH   SOLE   727,673 0 0
GOSSAMER BIO INC NOTE 5.000% 6/0 38341PAA0   3,488,296 9,573,000 PRN   SOLE   9,573,000 0 0
GOSSAMER BIO INC COM 38341P102 BBG00MVWLMC1 2,981,101 3,266,960 SH   SOLE   3,266,960 0 0
HUMANA INC COM 444859102 BBG001S5S1X6 141,921,100 310,000 SH   SOLE   310,000 0 0
ICOSAVAX INC COM 45114M109 BBG00QHK2J96 13,686,126 868,409 SH   SOLE   868,409 0 0
IDEXX LABS INC COM 45168D104 BBG001S5S4Y9 99,492,713 179,250 SH   SOLE   179,250 0 0
IMMATICS N.V SHS N44445109 BBG00VTL2J09 19,748,657 1,875,466 SH   SOLE   1,875,466 0 0
IMMUNOCORE HLDGS PLC ADS 45258D105 BBG00YYCXG54 181,834,158 2,661,507 SH   SOLE   2,661,507 0 0
IMMUNOGEN INC COM 45253H101 BBG001S6CTN1 22,515,172 759,365 SH   SOLE   759,365 0 0
IMMUNOVANT INC COM 45258J102 BBG00P5MC0R7 41,426,471 983,301 SH   SOLE   983,301 0 0
INHIBRX INC COM 45720L107 BBG00P80N9V6 11,453,200 301,400 SH Call SOLE   301,400 0 0
INOZYME PHARMA INC COM 45790W108 BBG00J7QJMD0 15,681,801 3,681,174 SH   SOLE   3,681,174 0 0
INSPIRE MED SYS INC COM 457730109 BBG00209SZK5 20,139,570 99,000 SH   SOLE   99,000 0 0
INSULET CORP COM 45784P101 BBG001SRF439 93,681,115 431,750 SH   SOLE   431,750 0 0
INTUITIVE SURGICAL INC COM NEW 46120E602 BBG001S7XR78 100,701,960 298,500 SH   SOLE   298,500 0 0
IRHYTHM TECHNOLOGIES INC COM 450056106 BBG001TSQV70 37,544,280 350,750 SH   SOLE   350,750 0 0
KARUNA THERAPEUTICS INC COM 48576A100 BBG00NN875H9 163,010,246 515,024 SH   SOLE   515,024 0 0
KRYSTAL BIOTECH INC COM 501147102 BBG00HDGRHJ5 12,898,394 103,969 SH   SOLE   103,969 0 0
KYMERA THERAPEUTICS INC COM 501575104 BBG00SDHC8F9 38,756,179 1,522,238 SH   SOLE   1,522,238 0 0
LEAP THERAPEUTICS INC COM NEW 52187K200 BBG00DQ929Z3 3,452,524 832,937 SH   SOLE   832,937 0 0
LEGEND BIOTECH CORP SPONSORED ADS 52490G102 BBG00TTGH6N2 29,630,355 492,444 SH   SOLE   492,444 0 0
LIFESTANCE HEALTH GROUP INC COM 53228F101 BBG01138DHT2 35,509,050 4,535,000 SH   SOLE   4,535,000 0 0
MACROGENICS INC COM 556099109 BBG001S9C8R7 11,340,018 1,178,796 SH   SOLE   1,178,796 0 0
MADRIGAL PHARMACEUTICALS INC COM 558868105 BBG001SNKQ42 45,852,343 198,169 SH   SOLE   198,169 0 0
MEREO BIOPHARMA GROUP PLC SPON ADS 589492107 BBG00KFWZCX7 18,442,696 7,983,851 SH   SOLE   7,983,851 0 0
MERSANA THERAPEUTICS INC COM 59045L106 BBG001TZ57P0 7,068,534 3,046,782 SH   SOLE   3,046,782 0 0
MERUS N V COM N5749R100 BBG00B8LXMT4 23,981,898 872,069 SH   SOLE   872,069 0 0
MINERALYS THERAPEUTICS INC COM 603170101 BBG00ZXN1GR9 10,040,431 1,167,492 SH   SOLE   1,167,492 0 0
MIRATI THERAPEUTICS INC COM 60468T105 BBG001SF6HK7 49,101,840 835,776 SH   SOLE   835,776 0 0
MIRUM PHARMACEUTICALS INC COM 604749101 BBG00MH7T2N6 54,655,217 1,851,464 SH   SOLE   1,851,464 0 0
NEUROCRINE BIOSCIENCES INC NOTE 2.250% 5/1 64125CAD1   1,753,490 1,000,000 PRN   SOLE   1,000,000 0 0
NEUROCRINE BIOSCIENCES INC COM 64125C109 BBG001S8W4X9 157,584,960 1,196,000 SH   SOLE   1,196,000 0 0
NEVRO CORP COM 64157F103 BBG001V0KW81 22,058,000 1,025,000 SH   SOLE   1,025,000 0 0
NEVRO CORP NOTE 2.750% 4/0 64157FAC7   481,796 500,000 PRN   SOLE   500,000 0 0
NOVAVAX INC COM NEW 670002401 BBG001SGL8G3 2,580,600 537,625 SH   SOLE   537,625 0 0
NUVATION BIO INC *W EXP 07/07/202 67080N119   8,042 134,028 SH   SOLE   134,028 0 0
OLINK HLDG AB SPONSORED ADS 680710100 BBG00ZHZXZ84 42,163,975 1,676,500 SH   SOLE   1,676,500 0 0
OSCAR HEALTH INC CL A 687793109 BBG00YMWFVT4 6,725,250 735,000 SH   SOLE   735,000 0 0
PACIRA BIOSCIENCES INC COM 695127100 BBG001S77N12 35,612,570 1,055,500 SH   SOLE   1,055,500 0 0
PENUMBRA INC COM 70975L107 BBG001TRHPB0 135,202,750 537,500 SH   SOLE   537,500 0 0
PHREESIA INC COM 71944F106 BBG001TG2W25 51,085,105 2,206,700 SH   SOLE   2,206,700 0 0
PLIANT THERAPEUTICS INC COM 729139105 BBG00C8083P2 6,972,278 384,996 SH   SOLE   384,996 0 0
PROTHENA CORP PLC SHS G72800108 BBG00393H6N0 22,714,244 625,048 SH   SOLE   625,048 0 0
PULMONX CORP COM 745848101 BBG001T4HJ52 8,318,100 652,400 SH   SOLE   652,400 0 0
RELAY THERAPEUTICS INC COM 75943R102 BBG00DSS08L8 7,420,366 673,966 SH   SOLE   673,966 0 0
RENEO PHARMACEUTICALS INC COM 75974E103 BBG00JVRSRD0 1,202,768 751,730 SH   SOLE   751,730 0 0
REVOLUTION MEDICINES INC COM 76155X100 BBG00829F4Q7 20,797,359 725,152 SH   SOLE   725,152 0 0
RHYTHM PHARMACEUTICALS INC COM 76243J105 BBG007DLZ629 70,007,391 1,522,893 SH   SOLE   1,522,893 0 0
SAGIMET BIOSCIENCES INC COM SER A 786700104 BBG0020584Z8 4,001,884 738,355 SH   SOLE   738,355 0 0
SAREPTA THERAPEUTICS INC COM 803607100 BBG001S6KJC6 31,590,468 327,600 SH   SOLE   327,600 0 0
SHOCKWAVE MED INC COM 82489T104 BBG005XVXMM4 22,867,200 120,000 SH   SOLE   120,000 0 0
SPRUCE BIOSCIENCES INC COM 85209E109 BBG00HYZ1559 7,644,736 2,609,125 SH   SOLE   2,609,125 0 0
STRUCTURE THERAPEUTICS INC SPONSORED ADS 86366E106 BBG01CBVHMQ6 11,684,914 286,676 SH   SOLE   286,676 0 0
TRAVERE THERAPEUTICS INC COM 89422G107 BBG001SL72C5 24,915,300 2,771,446 SH   SOLE   2,771,446 0 0
TRAVERE THERAPEUTICS INC NOTE 2.500% 9/1 761299AB2   2,767,863 3,250,000 PRN   SOLE   3,250,000 0 0
ULTRAGENYX PHARMACEUTICAL IN COM 90400D108 BBG001V2MJJ2 83,878,097 1,754,038 SH   SOLE   1,754,038 0 0
UNITEDHEALTH GROUP INC COM 91324P102 BBG001S6WCJ1 121,088,100 230,000 SH   SOLE   230,000 0 0
VIGIL NEUROSCIENCE INC COM 92673K108 BBG00YGBK4R3 1,595,218 471,958 SH   SOLE   471,958 0 0
VINCERX PHARMA INC COM NEW 92731L106 BBG00RRQXMY1 1,052,228 891,719 SH   SOLE   891,719 0 0
WARBY PARKER INC CL A COM 93403J106 BBG005DWN8L7 28,599,030 2,028,300 SH   SOLE   2,028,300 0 0
WEST PHARMACEUTICAL SVSC INC COM 955306105 BBG001S5XK22 48,328,470 137,250 SH   SOLE   137,250 0 0
XENON PHARMACEUTICALS INC COM 98420N105 BBG002VBMLS5 57,831,877 1,255,577 SH   SOLE   1,255,577 0 0
XILIO THERAPEUTICS INC COM 98422T100 BBG00M4D4XC8 792,417 1,440,759 SH   SOLE   1,440,759 0 0
ZAI LAB LTD ADR 98887Q104 BBG00HFX3P04 31,074,839 1,137,023 SH   SOLE   1,137,023 0 0