Exhibit 32.1

CERTIFICATION OF CHIEF EXECUTIVE OFFICER

PURSUANT TO 18 U.S.C. SECTION 1350, AS ADOPTED PURSUANT TO SECTION 906 OF THE SARBANES-OXLEY ACT OF 2002

In connection with the Annual Report of Tricida, Inc. (the “Company”), on Form 10-K for the fiscal year ended March 31, 2022, as filed with the Securities and Exchange Commission (the “Report”), Gerrit Klaerner, Ph.D., Chief Executive Officer and President of the Company, hereby certifies, pursuant to 18 U.S.C. Section 1350, as adopted pursuant to Section 906 of the Sarbanes-Oxley Act of 2002, that: 

•The Report fully complies with the requirements of Section 13(a) or 15(d) of the Securities Exchange Act of 1934; and

•The information contained in the Report fairly presents, in all material aspects, the financial condition and results of operations of the Company.

Dated: May 10, 2022

/s/ Gerrit Klaerner, Ph.D.

Gerrit Klaerner, Ph.D.

Chief Executive Officer and President

(Principal Executive Officer)

CERTIFICATION OF CHIEF FINANCIAL OFFICER

PURSUANT TO 18 U.S.C. SECTION 1350, AS ADOPTED PURSUANT TO SECTION 906 OF THE SARBANES-OXLEY ACT OF 2002

In connection with the Annual Report of Tricida, Inc. (the “Company”), on Form 10-K for the fiscal year ended March 31, 2022, as filed with the Securities and Exchange Commission (the “Report”), Geoffrey M. Parker, Chief Operating Officer, Chief Financial Officer and Executive Vice President of the Company, hereby certifies, pursuant to 18 U.S.C. Section 1350, as adopted pursuant to Section 906 of the Sarbanes-Oxley Act of 2002, that: 

•The Report fully complies with the requirements of Section 13(a) or 15(d) of the Securities Exchange Act of 1934; and

•The information contained in the Report fairly presents, in all material aspects, the financial condition and results of operations of the Company.

Dated: May 10, 2022

/s/ Geoffrey M. Parker

Geoffrey M. Parker

Chief Operating Officer, Chief Financial Officer and Executive Vice President

(Principal Financial Officer)