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Note 4 - Investment Unit (Details Textual) - USD ($)
1 Months Ended 12 Months Ended
Apr. 03, 2018
Mar. 12, 2014
Dec. 31, 2013
Dec. 31, 2020
Dec. 31, 2019
Dec. 31, 2018
Class of Warrant or Right, Exercise Price of Warrants or Rights (in dollars per share)       $ 4.37 $ 1.45 $ 2.36
Stock Issued During Period, Shares, New Issues (in shares)       5,511,599    
Fair Value Adjustment of Warrants     $ 2,500,000 $ 0    
Conversion of Preferred Stock to Common Stock [Member]            
Conversion of Stock, Shares Issued (in shares) 1,235,219     9,324,177    
Series B Preferred Stock [Member]            
Stock Issued During Period, Shares, New Issues (in shares)   184,797        
Warrant Issued to TETF [Member]            
Class of Warrant or Right, Purchase Percentage         80.00%  
Warrant Discount Rate         20.00%  
Class of Warrant or Right, Exercise Price of Warrants or Rights (in dollars per share)   $ 0.001     $ 0.001  
Promissory Note [Member]            
Contingent Debt         $ 4,500,000  
Contingent Debt, Interest Rate         8.00%