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Condensed Consolidated Statement of Stockholders' Equity (Unaudited) - USD ($)
Total
Common Stock [Member]
Additional Paid-in Capital [Member]
Accumulated Deficit [Member]
AOCI Attributable to Parent [Member]
Beginning balance, value at Dec. 31, 2021 $ 69,108,027 $ 416 $ 418,903,820 $ (349,733,764) $ (62,445)
Beginning balance, shares at Dec. 31, 2021   4,169,631      
Issuance of common stock, net of issuance costs 1 $ 1      
Issuance of common stock, net of issuance costs, shares   1,250      
Stock-based compensation expense 3,104,835   3,104,835    
Change in unrealized gain (loss) on marketable debt securities (56,875)       (56,875)
Net loss (22,686,130)     (22,686,130)  
Ending balance, value at Jun. 30, 2022 49,469,858 $ 417 422,008,655 (372,419,894) (119,320)
Ending balance, shares at Jun. 30, 2022   4,170,881      
Beginning balance, value at Mar. 31, 2022 61,155,284 $ 417 420,495,566 (359,171,006) (169,693)
Beginning balance, shares at Mar. 31, 2022   4,170,464      
Issuance of common stock, net of issuance costs, shares   417      
Stock-based compensation expense 1,513,089   1,513,089    
Change in unrealized gain (loss) on marketable debt securities 50,373       50,373
Net loss (13,248,888)     (13,248,888)  
Ending balance, value at Jun. 30, 2022 49,469,858 $ 417 422,008,655 (372,419,894) (119,320)
Ending balance, shares at Jun. 30, 2022   4,170,881      
Beginning balance, value at Dec. 31, 2022 32,990,017 $ 417 425,196,359 (392,080,667) (126,092)
Beginning balance, shares at Dec. 31, 2022   4,171,297      
Issuance of common stock, net of issuance costs 102,419 $ 1 102,418    
Issuance of common stock, net of issuance costs, shares   13,164      
Stock-based compensation expense 1,849,754   1,849,754    
Issuance of common stock upon exercise of stock options 129,745 $ 5 129,740    
Issuance of common stock upon exercise of stock options, shares   43,836      
Change in unrealized gain (loss) on marketable debt securities (102,304)       102,304
Issuance of common stock upon conversion of K2 Loan and Security Agreement, Shares   194,444      
Issuance of common stock upon conversion of K2 Loan and Security Agreement, Value 875,000 $ 19 874,981    
Net loss (26,528,653)     (26,528,653)  
Ending balance, value at Jun. 30, 2023 9,520,586 $ 442 428,153,252 (418,609,320) (23,788)
Ending balance, shares at Jun. 30, 2023   4,422,741      
Beginning balance, value at Mar. 31, 2023 16,458,952 $ 422 426,352,478 (409,825,479) (68,469)
Beginning balance, shares at Mar. 31, 2023   4,215,133      
Issuance of common stock, net of issuance costs 102,419 $ 1 102,418    
Issuance of common stock, net of issuance costs, shares   13,164      
Stock-based compensation expense 823,375   823,375    
Change in unrealized gain (loss) on marketable debt securities (44,681)       44,681
Issuance of common stock upon conversion of K2 Loan and Security Agreement, Shares   194,444      
Issuance of common stock upon conversion of K2 Loan and Security Agreement, Value 875,000 $ 19 874,981    
Net loss (8,783,841)     (8,783,841)  
Ending balance, value at Jun. 30, 2023 $ 9,520,586 $ 442 $ 428,153,252 $ (418,609,320) $ (23,788)
Ending balance, shares at Jun. 30, 2023   4,422,741