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Revenue to be recognized.

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Royalty payment percentage.

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Carrying value as of the balance sheet date of obligations incurred through that date and payable for royalties. Used to reflect the current portion of the liabilities (due within one year or within the normal operating cycle if longer).

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Amount of increase in additional paid in capital (APIC) resulting from the issuance of warrants. Includes allocation of proceeds of debt securities issued with detachable stock purchase warrants.

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Exercise price per share or per unit of warrants or rights outstanding.

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Number of securities into which each warrant or right may be converted. For example, but not limited to, each warrant may be converted into two shares.

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The amount or range of possible amounts of gain that could be realized upon the resolution of a contingency.

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The amount of cash paid for royalties during the current period.

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Amount, excluding tax collected from customer, of revenue from satisfaction of performance obligation by transferring promised good or service to customer. Tax collected from customer is tax assessed by governmental authority that is both imposed on and concurrent with specific revenue-producing transaction, including, but not limited to, sales, use, value added and excise.

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Expiration date of outstanding warrant and right embodying unconditional obligation requiring redemption by transferring asset at specified or determinable date or upon event certain to occur, in YYYY-MM-DD format.

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DEVELOPMENT AWARDS AND DEFERRED REVENUE (Details Narrative) - USD ($)			1 Months Ended	12 Months Ended
	Jul. 31, 2020	Jan. 26, 2018	May 31, 2019	Dec. 31, 2022	Dec. 31, 2021	Dec. 31, 2020	Dec. 31, 2019	Dec. 31, 2018
Entity Listings [Line Items]
Revenue				$ 0	$ 881,705
CFF Warrant [Member]
Entity Listings [Line Items]
Warrant exercisable price per share				$ 396
Cystic Fibrosis Program Related Investment Agreement [Member] \| Phase 2b Clinical Trial [Member]
Entity Listings [Line Items]
Accrued Royalties, Current			$ 2,700,000
Payments for Royalties			$ 27,000,000
Proceeds from investments on achieving milestones				$ 25,000,000
Cystic Fibrosis Program Related Investment Agreement [Member] \| Maximum [Member]
Entity Listings [Line Items]
Gain Contingency, Unrecorded Amount		$ 25,000,000
Investment Agreement [Member] \| 2018 CFF Award [Member]
Entity Listings [Line Items]
Revenue				$ 0	881,705
Investment Agreement [Member] \| CFF Warrant [Member]
Entity Listings [Line Items]
Class of Warrant or Right, Number of Securities Called by Each Warrant or Right				33,333
Warrants and Rights Outstanding, Maturity Date				Jan. 26, 2025
Investment Agreement [Member] \| CFF Warrant [Member] \| Immediately Exercisable Warrants [Member]
Entity Listings [Line Items]
Class of Warrant or Right, Number of Securities Called by Each Warrant or Right				16,667
Investment Agreements [Member]
Entity Listings [Line Items]
Revenue	$ 25,000,000				$ 2,500,000	$ 5,000,000	$ 5,000,000	$ 12,500,000
Investment Agreements [Member] \| CFF Warrant [Member] \| Warrants Exercisable On Completion Of Final Milestone [Member]
Entity Listings [Line Items]
Class of Warrant or Right, Number of Securities Called by Each Warrant or Right				16,667
Investment Agreements [Member] \| Cystic Fibrosis Foundation Warrants [Member]
Entity Listings [Line Items]
Revenue				$ 25,000,000
Adjustments to Additional Paid in Capital, Warrant Issued				6,215,225
Revenue to be recognized				18,784,775
Investment Agreements [Member] \| Cystic Fibrosis Foundation [Member] \| CFF Warrant [Member]
Entity Listings [Line Items]
Adjustments to Additional Paid in Capital, Warrant Issued				$ 6,215,225
Collaboration Agreement [Member] \| Cystic Fibrosis Foundation [Member]
Entity Listings [Line Items]
Royalty payment percentage		10.00%