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Significant Agreements - Schedule of License Revenue (Detail) - USD ($)
$ in Thousands
3 Months Ended 9 Months Ended
Sep. 30, 2016
Sep. 30, 2015
Sep. 30, 2016
Sep. 30, 2015
License Agreement Revenue Recognition [Abstract]        
Up-front fees and option fees for commercial licenses   $ 1,000 $ 2,000 $ 2,000
Maintenance fees for commercial licenses $ 65 65 395 245
Milestone fees       250
Research and other license revenue     243 140
Licenses revenue including amounts from related parties $ 65 $ 1,065 $ 2,638 $ 2,635