Commitments and Contingencies (Tables)

9 Months Ended

Sep. 30, 2016

Schedule of Future Minimum Lease Payments Under Non-Cancelable Operating Leases

As of September 30, 2016, future minimum lease payments under non-cancelable operating leases are as follows:

	Operating
	Leases
2016 (remainder of year)	$	387
2017		1,589
2018		1,637
2019		1,685
2020		1,611
Thereafter		1,614
Total minimum lease payments	$	8,523

The Trustees of the University of Pennsylvania [Member]

Summary of Expenses Incurred by Company

Expenses incurred by the Company related to its license from Penn were as follows:

	Three Months Ended September 30,				Nine Months Ended September 30,
	2016		2015		2016		2015
Sublicense fees	$	7	$	107	$	264	$	264
Royalties on sales of reagents		2		2		11		8
Maintenance of licensed patents		42		29		85		118
	$	51	$	138	$	360	$	390

GlaxoSmithKline LLC [Member]

Summary of Expenses Incurred by Company

Expenses incurred by the Company related to its license from GSK were as follows:

	Three Months Ended September 30,				Nine Months Ended September 30,
	2016		2015		2016		2015
Sublicense fees	$	7	$	107	$	264	$	264
Royalties on sales of reagents		1		1		7		5
Maintenance of licensed patents		89		57		319		474
	$	97	$	165	$	590	$	743