Commitments and Contingencies (Tables)

3 Months Ended

Mar. 31, 2016

Schedule of Future Minimum Lease Payments Under Non-Cancelable Operating Leases

As of March 31, 2016, future minimum lease payments under non-cancelable operating leases are as follows:

	Operating
	Leases
2016 (remainder of year)	$	848
2017		1,286
2018		1,325
2019		1,365
2020		1,337
Thereafter		1,614
Total minimum lease payments	$	7,775

The Trustees of the University of Pennsylvania [Member]

Summary of Expenses Incurred by Company

Expenses incurred by the Company related to its license from Penn were as follows:

	Three Months Ended March 31,
	2016		2015
Sublicense fees	$	33	$	10
Royalties on sales of reagents		2		1
Maintenance of licensed patents		29		10
	$	64	$	21

GlaxoSmithKline LLC [Member]

Summary of Expenses Incurred by Company

Expenses incurred by the Company related to its license from GSK were as follows:

	Three Months Ended March 31,
	2016		2015
Sublicense fees	$	33	$	10
Royalties on sales of reagents		1		1
Maintenance of licensed patents		92		114
	$	126	$	125