Consolidated Statements of Operations and Comprehensive Loss - USD ($) shares in Thousands, $ in Thousands	3 Months Ended		9 Months Ended
	Sep. 30, 2024	Sep. 30, 2023	Sep. 30, 2024	Sep. 30, 2023
Revenues
Revenues	$ 24,197	$ 28,914	$ 62,114	$ 68,029
Operating Expenses
Cost of revenues	12,387	12,388	27,249	25,975
Research and development	54,429	58,183	158,142	176,585
General and administrative	19,422	23,083	56,568	69,415
Impairment of long-lived assets			2,101
Other operating expenses	37	220	32	279
Total operating expenses	86,275	93,874	244,092	272,254
Loss from operations	(62,078)	(64,960)	(181,978)	(204,225)
Other Income (Expense)
Interest income from licensing	25	56	91	166
Investment income	3,276	4,660	9,213	8,953
Interest expense	(820)	(1,624)	(3,242)	(5,499)
Total other income	2,481	3,092	6,062	3,620
Net loss	(59,597)	(61,868)	(175,916)	(200,605)
Other Comprehensive Income
Unrealized gain on available-for-sale securities, net	1,684	2,685	3,847	7,988
Total other comprehensive income	1,684	2,685	3,847	7,988
Comprehensive loss	$ (57,913)	$ (59,183)	$ (172,069)	$ (192,617)
Net loss per share, basic	$ (1.17)	$ (1.41)	$ (3.59)	$ (4.6)
Net loss per share, diluted	$ (1.17)	$ (1.41)	$ (3.59)	$ (4.6)
Weighted-average common shares outstanding, basic	50,800	43,945	49,051	43,644
Weighted-average common shares outstanding, diluted	50,800	43,945	49,051	43,644
License and royalty [Member]
Revenues
Revenues	$ 24,197	$ 28,914	$ 62,114	$ 68,029