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CONDENSED CONSOLIDATED STATEMENTS OF CHANGES IN STOCKHOLDERS’ EQUITY - USD ($)
$ in Thousands
Total
Preferred Stock
Series A Preferred Stock
Preferred Stock
Series B Preferred Stock
Common Stock
Additional Paid-in Capital
Accumulated Other Comprehensive Loss
Accumulated Deficit
Beginning balance (in shares) at Dec. 31, 2020   398,487 0 4,231,135      
Beginning balance at Dec. 31, 2020 $ 120,037 $ 180,801 $ 0 $ 42 $ 218,089 $ (8) $ (278,887)
Stockholders’ deficit              
Issuance of common stock upon the conversion of convertible preferred stock (in shares)   (43,664)   2,911,071      
Issuance of common stock upon the conversion of convertible preferred stock 0 $ (19,811)   $ 29 19,782    
Issuance of common stock upon exercise of warrants (in shares)       56,935      
Issuance of common stock upon exercises of warrants 940     $ 1 939    
Issuance of common stock for exercises of stock options and vesting of restricted stock units (in shares)       31,249      
Issuance of common stock for exercises of stock options and vesting of restricted stock units 307       307    
Issuance of common stock for cash under employee stock purchase plan (in shares)       980      
Issuance of common stock for cash under employee stock purchase plan 12       12    
Share-based compensation expense 3,175       3,175    
Change in unrealized loss on investments (13)         (13)  
Net loss (18,460)           (18,460)
Ending balance (in shares) at Mar. 31, 2021   354,823 0 7,231,370      
Ending balance at Mar. 31, 2021 105,998 $ 160,990 $ 0 $ 72 242,304 (21) (297,347)
Beginning balance (in shares) at Dec. 31, 2020   398,487 0 4,231,135      
Beginning balance at Dec. 31, 2020 120,037 $ 180,801 $ 0 $ 42 218,089 (8) (278,887)
Stockholders’ deficit              
Change in unrealized loss on investments (4)            
Net loss (36,424)            
Ending balance (in shares) at Jun. 30, 2021   340,219 0 8,608,886      
Ending balance at Jun. 30, 2021 98,912 $ 154,363 $ 0 $ 86 259,786 (12) (315,311)
Beginning balance (in shares) at Mar. 31, 2021   354,823 0 7,231,370      
Beginning balance at Mar. 31, 2021 105,998 $ 160,990 $ 0 $ 72 242,304 (21) (297,347)
Stockholders’ deficit              
Issuance of common stock upon the conversion of convertible preferred stock (in shares)   (14,604)   973,648      
Issuance of common stock upon the conversion of convertible preferred stock 0 $ (6,627)   $ 10 6,617    
Issuance of stock, net of issuance cost (in shares)       403,868      
Issuance of stock, net of issuance cost 7,052     $ 4 7,048    
Share-based compensation expense 3,817       3,817    
Change in unrealized loss on investments 9         9  
Net loss (17,964)           (17,964)
Ending balance (in shares) at Jun. 30, 2021   340,219 0 8,608,886      
Ending balance at Jun. 30, 2021 98,912 $ 154,363 $ 0 $ 86 259,786 (12) (315,311)
Beginning balance (in shares) at Dec. 31, 2021   260,437 23,126 23,924,004      
Beginning balance at Dec. 31, 2021 187,716 $ 118,164 $ 15,669 $ 239 412,101 (157) (358,300)
Stockholders’ deficit              
Issuance of common stock upon the conversion of convertible preferred stock (in shares)   (47,871)   3,191,555      
Issuance of common stock upon the conversion of convertible preferred stock 0 $ (21,722)   $ 33 21,689    
Issuance of common stock for exercises of stock options and vesting of restricted stock units (in shares)       47,735      
Issuance of common stock for exercises of stock options and vesting of restricted stock units 667       667    
Issuance of common stock for cash under employee stock purchase plan (in shares)       6,128      
Issuance of common stock for cash under employee stock purchase plan 71       71    
Share-based compensation expense 4,659       4,659    
Change in unrealized loss on investments (778)         (778)  
Net loss (25,693)           (25,693)
Ending balance (in shares) at Mar. 31, 2022   212,566 23,126 27,169,422      
Ending balance at Mar. 31, 2022 166,642 $ 96,442 $ 15,669 $ 272 439,187 (935) (383,993)
Beginning balance (in shares) at Dec. 31, 2021   260,437 23,126 23,924,004      
Beginning balance at Dec. 31, 2021 187,716 $ 118,164 $ 15,669 $ 239 412,101 (157) (358,300)
Stockholders’ deficit              
Change in unrealized loss on investments (920)            
Net loss (55,184)            
Ending balance (in shares) at Jun. 30, 2022   193,539 23,126 28,463,980      
Ending balance at Jun. 30, 2022 141,898 $ 87,809 $ 15,669 $ 285 452,696 (1,077) (413,484)
Beginning balance (in shares) at Mar. 31, 2022   212,566 23,126 27,169,422      
Beginning balance at Mar. 31, 2022 166,642 $ 96,442 $ 15,669 $ 272 439,187 (935) (383,993)
Stockholders’ deficit              
Issuance of common stock upon the conversion of convertible preferred stock (in shares)   (19,027)   1,268,528      
Issuance of common stock upon the conversion of convertible preferred stock 0 $ (8,633)   $ 13 8,620    
Issuance of common stock for exercises of stock options and vesting of restricted stock units (in shares)       26,030      
Issuance of common stock for exercises of stock options and vesting of restricted stock units 4       4    
Share-based compensation expense 4,885       4,885    
Change in unrealized loss on investments (142)         (142)  
Net loss (29,491)           (29,491)
Ending balance (in shares) at Jun. 30, 2022   193,539 23,126 28,463,980      
Ending balance at Jun. 30, 2022 $ 141,898 $ 87,809 $ 15,669 $ 285 $ 452,696 $ (1,077) $ (413,484)