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CONDENSED CONSOLIDATED STATEMENTS OF CHANGES IN STOCKHOLDERS' EQUITY - USD ($)
$ in Thousands
Total
Public offering
At-the-market
Private placement
Common Stock
Common Stock
Public offering
Common Stock
At-the-market
Common Stock
Private placement
Additional Paid-in Capital
Additional Paid-in Capital
Public offering
Additional Paid-in Capital
At-the-market
Additional Paid-in Capital
Private placement
Accumulated Other Comprehensive Gain (Loss)
Accumulated Deficit
Beginning balance (in shares) at Dec. 31, 2017         22,568,006                  
Beginning balance at Dec. 31, 2017 $ 38,510       $ 226       $ 131,877       $ 0 $ (93,593)
Stockholders’ deficit                            
Issuance of common stock, net of issuance cost (in shares)           7,414,996                
Issuance of common stock, net of issuance cost   $ 37,845       $ 74       $ 37,771        
Shares issued for cash upon the exercise of stock options (in shares)         179,598                  
Shares issued for cash upon the exercise of stock options 112       $ 2       110          
Issuance of common stock for cash under employee stock purchase plan (in shares)         23,940                  
Issuance of common stock for cash under employee stock purchase plan 110               110          
Share-based compensation expense 790               790          
Net loss (4,661)                         (4,661)
Ending balance (in shares) at Mar. 31, 2018         30,186,540                  
Ending balance at Mar. 31, 2018 72,706       $ 302       170,658       0 (98,254)
Beginning balance (in shares) at Dec. 31, 2017         22,568,006                  
Beginning balance at Dec. 31, 2017 38,510       $ 226       131,877       0 (93,593)
Stockholders’ deficit                            
Change in unrealized gain on investments (6)                          
Net loss (22,386)                          
Ending balance (in shares) at Sep. 30, 2018         30,833,367                  
Ending balance at Sep. 30, 2018 60,718       $ 308       176,395       (6) (115,979)
Beginning balance (in shares) at Mar. 31, 2018         30,186,540                  
Beginning balance at Mar. 31, 2018 72,706       $ 302       170,658       0 (98,254)
Stockholders’ deficit                            
Issuance of common stock, net of issuance cost (in shares)             372,852              
Issuance of common stock, net of issuance cost     $ 2,657       $ 4       $ 2,653      
Shares issued for cash upon the exercise of stock options (in shares)         36,401                  
Shares issued for cash upon the exercise of stock options 34       $ 0       34          
Share-based compensation expense 984               984          
Change in unrealized gain on investments 4                       4  
Net loss (8,714)                         (8,714)
Ending balance (in shares) at Jun. 30, 2018         30,595,793                  
Ending balance at Jun. 30, 2018 67,671       $ 306       174,329       4 (106,968)
Stockholders’ deficit                            
Issuance of common stock, net of issuance cost (in shares)               150,987            
Issuance of common stock, net of issuance cost       $ 935       $ 2       $ 933    
Shares issued for cash upon the exercise of stock options (in shares)         58,083                  
Shares issued for cash upon the exercise of stock options 33       $ 0       33          
Issuance of common stock for cash under employee stock purchase plan (in shares)         28,504                  
Issuance of common stock for cash under employee stock purchase plan 132               132          
Share-based compensation expense 968               968          
Change in unrealized gain on investments (10)                       (10)  
Net loss (9,011)                         (9,011)
Ending balance (in shares) at Sep. 30, 2018         30,833,367                  
Ending balance at Sep. 30, 2018 $ 60,718       $ 308       176,395       (6) (115,979)
Beginning balance (in shares) at Dec. 31, 2018 30,839,463       30,839,463                  
Beginning balance at Dec. 31, 2018 $ 51,344       $ 308       177,335       (3) (126,296)
Stockholders’ deficit                            
Issuance of common stock, net of issuance cost (in shares)             47,589              
Issuance of common stock, net of issuance cost     134       $ 1       133      
Issuance of common stock for cash under employee stock purchase plan (in shares)         34,167                  
Issuance of common stock for cash under employee stock purchase plan 84               84          
Share-based compensation expense 1,018               1,018          
Change in unrealized gain on investments 5                       5  
Net loss (11,629)                         (11,629)
Ending balance (in shares) at Mar. 31, 2019         30,921,219                  
Ending balance at Mar. 31, 2019 $ 40,956       $ 309       178,570       2 (137,925)
Beginning balance (in shares) at Dec. 31, 2018 30,839,463       30,839,463                  
Beginning balance at Dec. 31, 2018 $ 51,344       $ 308       177,335       (3) (126,296)
Stockholders’ deficit                            
Change in unrealized gain on investments 6                          
Net loss $ (31,755)                          
Ending balance (in shares) at Sep. 30, 2019 31,181,749       31,181,749                  
Ending balance at Sep. 30, 2019 $ 23,169       $ 312       180,905       3 (158,051)
Beginning balance (in shares) at Mar. 31, 2019         30,921,219                  
Beginning balance at Mar. 31, 2019 40,956       $ 309       178,570       2 (137,925)
Stockholders’ deficit                            
Issuance of common stock, net of issuance cost (in shares)             96,652              
Issuance of common stock, net of issuance cost     $ 278       $ 1       $ 277      
Shares issued for cash upon the exercise of stock options (in shares)         19,492                  
Shares issued for cash upon the exercise of stock options 15       $ 0       15          
Share-based compensation expense 1,075               1,075          
Change in unrealized gain on investments 9                       9  
Net loss (8,896)                         (8,896)
Ending balance (in shares) at Jun. 30, 2019         31,037,363                  
Ending balance at Jun. 30, 2019 33,437       $ 310       179,937       11 (146,821)
Stockholders’ deficit                            
Shares issued for cash upon the exercise of stock options (in shares)         122,300                  
Shares issued for cash upon the exercise of stock options 70       $ 1       69          
Issuance of common stock for cash under employee stock purchase plan (in shares)         22,086                  
Issuance of common stock for cash under employee stock purchase plan 26       $ 1       25          
Share-based compensation expense 874               874          
Change in unrealized gain on investments (8)                       (8)  
Net loss $ (11,230)                         (11,230)
Ending balance (in shares) at Sep. 30, 2019 31,181,749       31,181,749                  
Ending balance at Sep. 30, 2019 $ 23,169       $ 312       $ 180,905       $ 3 $ (158,051)