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Property and Equipment - Components of Property and Equipment (Details) - USD ($)
$ in Thousands
Sep. 30, 2019
Dec. 31, 2018
Property, Plant and Equipment [Line Items]    
Property and equipment $ 3,887 $ 3,817
Less: accumulated depreciation and amortization (3,291) (3,090)
Property and equipment, net 596 727
Lab equipment    
Property, Plant and Equipment [Line Items]    
Property and equipment 2,519 2,489
Leasehold improvements    
Property, Plant and Equipment [Line Items]    
Property and equipment 741 741
Computer hardware and software    
Property, Plant and Equipment [Line Items]    
Property and equipment 461 428
Furniture and fixtures    
Property, Plant and Equipment [Line Items]    
Property and equipment $ 166 $ 159