The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
ABEONA THERAPEUTICS INC COM 00289Y107 261 35,468 SH   OTR   0 35,468 0
ACCELERON PHARMA INC COM 00434H108 271 5,810 SH   OTR   0 5,810 0
ACHILLION PHARMACEUTICALS IN COM 00448Q201 257 86,904 SH   OTR   0 86,904 0
ACORDA THERAPEUTICS INC COM 00484M106 644 48,468 SH   OTR   0 48,468 0
ADAPTIMMUNE THERAPEUTICS PLC SPONDS ADR 00653A107 218 50,655 SH   OTR   0 50,655 0
ADOBE INC COM 00724F101 39 146 SH   OTR   0 146 0
ADVANCE AUTO PARTS INC COM 00751Y106 16 92 SH   OTR   0 92 0
AGENUS INC COM NEW 00847G705 319 107,479 SH   OTR   0 107,479 0
AGILENT TECHNOLOGIES INC COM 00846U101 27 333 SH   OTR   0 333 0
AGIOS PHARMACEUTICALS INC COM 00847X104 981 14,540 SH   OTR   0 14,540 0
AIMMUNE THERAPEUTICS INC COM 00900T107 268 11,993 SH   OTR   0 11,993 0
AKCEA THERAPEUTICS INC COM 00972L107 242 8,527 SH   OTR   0 8,527 0
AKEBIA THERAPEUTICS INC COM 00972D105 274 33,514 SH   OTR   0 33,514 0
ALIBABA GROUP HLDG LTD SPONSORED ADS 01609W102 94 516 SH   OTR   0 516 0
ALLAKOS INC COM 01671P100 180 4,437 SH   OTR   0 4,437 0
ALNYLAM PHARMACEUTICALS INC COM 02043Q107 959 10,262 SH   OTR   0 10,262 0
AMBEV SA SPONSORED ADR 02319V103 32 7,354 SH   OTR   0 7,354 0
AMERICA MOVIL SAB DE CV SPON ADR L SHS 02364W105 72 5,040 SH   OTR   0 5,040 0
AMICUS THERAPEUTICS INC COM 03152W109 1,002 73,653 SH   OTR   0 73,653 0
AMYRIS INC COM NEW 03236M200 137 65,658 SH   OTR   0 65,658 0
APELLIS PHARMACEUTICALS INC COM 03753U106 280 14,338 SH   OTR   0 14,338 0
APTINYX INC COM 03836N103 50 12,427 SH   OTR   0 12,427 0
ARRAY BIOPHARMA INC COM 04269X105 1,193 48,922 SH   OTR   0 48,922 0
ARROWHEAD PHARMACEUTICALS IN COM 04280A100 333 18,120 SH   OTR   0 18,120 0
ASCENDIS PHARMA A S SPONSORED ADR 04351P101 500 4,250 SH   OTR   0 4,250 0
ASSERTIO THERAPEUTICS INC COM 04545L107 326 64,315 SH   OTR   0 64,315 0
ATHENE HLDG LTD CL A G0684D107 14 333 SH   OTR   0 333 0
ATHENEX INC COM 04685N103 263 21,463 SH   OTR   0 21,463 0
AUDENTES THERAPEUTICS INC COM 05070R104 457 11,716 SH   OTR   0 11,716 0
AUTOHOME INC SP ADR RP CL A 05278C107 8 75 SH   OTR   0 75 0
AUTOLUS THERAPEUTICS PLC SPON ADS 05280R100 265 8,434 SH   OTR   0 8,434 0
AVROBIO INC COM 05455M100 239 10,850 SH   OTR   0 10,850 0
BEIGENE LTD SPONSORED ADR 07725L102 269 2,041 SH   OTR   0 2,041 0
BIOCRYST PHARMACEUTICALS COM 09058V103 255 31,277 SH   OTR   0 31,277 0
BIOGEN INC COM 09062X103 562 2,376 SH   OTR   0 2,376 0
BIOHAVEN PHARMACTL HLDG CO L COM G11196105 381 7,409 SH   OTR   0 7,409 0
BIOMARIN PHARMACEUTICAL INC COM 09061G101 736 8,285 SH   OTR   0 8,285 0
BLUEBIRD BIO INC COM 09609G100 415 2,635 SH   OTR   0 2,635 0
BLUEPRINT MEDICINES CORP COM 09627Y109 380 4,741 SH   OTR   0 4,741 0
C H ROBINSON WORLDWIDE INC COM NEW 12541W209 18 204 SH   OTR   0 204 0
CAPITAL ONE FINL CORP COM 14040H105 25 304 SH   OTR   0 304 0
CARDINAL HEALTH INC COM 14149Y108 12 243 SH   OTR   0 243 0
CHEMOCENTRYX INC COM 16383L106 367 26,452 SH   OTR   0 26,452 0
CORBUS PHARMACEUTICALS HLDGS COM 21833P103 282 40,628 SH   OTR   0 40,628 0
COSTAR GROUP INC COM 22160N109 32 68 SH   OTR   0 68 0
CRINETICS PHARMACEUTICALS IN COM 22663K107 181 7,934 SH   OTR   0 7,934 0
CTRIP COM INTL LTD SPONSORED ADS 22943F100 9 196 SH   OTR   0 196 0
CYMABAY THERAPEUTICS INC COM 23257D103 411 30,947 SH   OTR   0 30,947 0
CYTOKINETICS INC COM NEW 23282W605 273 33,758 SH   OTR   0 33,758 0
CYTOMX THERAPEUTICS INC COM 23284F105 194 18,085 SH   OTR   0 18,085 0
DECIPHERA PHARMACEUTICALS IN COM 24344T101 246 10,578 SH   OTR   0 10,578 0
DENALI THERAPEUTICS INC COM 24823R105 307 13,201 SH   OTR   0 13,201 0
DOMINION ENERGY INC COM 25746U109 14 179 SH   OTR   0 179 0
DXC TECHNOLOGY CO COM 23355L106 12 192 SH   OTR   0 192 0
EAST WEST BANCORP INC COM 27579R104 16 339 SH   OTR   0 339 0
EIDOS THERAPEUTICS INC COM 28249H104 413 17,604 SH   OTR   0 17,604 0
EMBRAER S A SPONSORED ADS 29082A107 5 284 SH   OTR   0 284 0
ENANTA PHARMACEUTICALS INC COM 29251M106 1,016 10,634 SH   OTR   0 10,634 0
EPIZYME INC COM 29428V104 563 45,462 SH   OTR   0 2,955 0
EQUITY RESIDENTIAL SH BEN INT 29476L107 28 371 SH   OTR   0 371 0
ESPERION THERAPEUTICS INC NE COM 29664W105 220 5,483 SH   OTR   0 5,483 0
EVEREST RE GROUP LTD COM G3223R108 16 72 SH   OTR   0 72 0
EXELIXIS INC COM 30161Q104 867 36,441 SH   OTR   0 36,441 0
FACEBOOK INC CL A 30303M102 73 435 SH   OTR   0 435 0
FATE THERAPEUTICS INC COM 31189P102 292 16,612 SH   OTR   0 4,540,270 0
FIBROGEN INC COM 31572Q808 372 6,840 SH   OTR   0 4,540,270 0
FIVE PRIME THERAPEUTICS INC COM 33830X104 368 27,492 SH   OTR   0 4,540,270 0
FRANKLIN TEMPLETON ETF TR FRANKLIN INDIA 35473P769 668 28,491 SH   OTR   0 28,491 0
FREEPORT-MCMORAN INC CL B 35671D857 15 1,194 SH   OTR   0 8,000 0
G1 THERAPEUTICS INC COM 3621LQ109 144 8,654 SH   OTR   0 8,654 0
GENERAL MTRS CO COM 37045V100 22 585 SH   OTR   0 585 0
GLOBAL BLOOD THERAPEUTICS IN COM 37890U108 336 6,342 SH   OTR   0 6,342 0
GLYCOMIMETICS INC COM 38000Q102 331 26,550 SH   OTR   0 26,550 0
GRUPO TELEVISA SA SPON ADR REP ORD 40049J206 26 2,307 SH   OTR   0 2,307 0
HALOZYME THERAPEUTICS INC COM 40637H109 818 50,835 SH   OTR   0 50,835 0
HDFC BANK LTD SPONSORED ADS 40415F101 92 798 SH   OTR   0 798 0
HP INC COM 40434L105 25 1,280 SH   OTR   0 1,280 0
HUAZHU GROUP LTD SPONSORED ADS 44332N106 29 684 SH   OTR   0 684 0
ICICI BK LTD ADR 45104G104 48 4,196 SH   OTR   0 4,196 0
IDEX CORP COM 45167R104 25 165 SH   OTR   0 165 0
IMMUNOGEN INC COM 45253H101 136 50,045 SH   OTR   0 50,045 0
INCYTE CORP COM 45337C102 990 11,513 SH   OTR   0 11,513 0
INOVIO PHARMACEUTICALS INC COM NEW 45773H201 197 52,943 SH   OTR   0 52,943 0
INTERCEPT PHARMACEUTICALS IN COM 45845P108 798 7,138 SH   OTR   0 7,138 0
INTRA CELLULAR THERAPIES INC COM 46116X101 230 18,878 SH   OTR   0 18,878 0
INTUITIVE SURGICAL INC COM NEW 46120E602 18 32 SH   OTR   0 32 0
INVESCO LTD SHS G491BT108 18 952 SH   OTR   0 952 0
IRONWOOD PHARMACEUTICALS INC COM CL A 46333X108 931 68,811 SH   OTR   0 68,811 0
JD COM INC SPON ADR CL A 47215P106 24 805 SH   OTR   0 805 0
KADMON HLDGS INC COM 48283N106 317 119,987 SH   OTR   0 119,987 0
KARYOPHARM THERAPEUTICS INC COM 48576U106 160 27,391 SH   OTR   0 27,391 0
KEYSIGHT TECHNOLOGIES INC COM 49338L103 26 296 SH   OTR   0 296 0
KINIKSA PHARMACEUTICALS LTD COM CL A G5269C101 212 11,763 SH   OTR   0 11,763 0
KT CORP SPONSORED ADR 48268K101 4 296 SH   OTR   0 296 0
KURA ONCOLOGY INC COM 50127T109 323 19,441 SH   OTR   0 19,441 0
LIBERTY GLOBAL PLC SHS CL A G5480U104 25 1,003 SH   OTR   0 1,003 0
LIGAND PHARMACEUTICALS INC COM NEW 53220K504 692 5,503 SH   OTR   0 5,503 0
LYONDELLBASELL INDUSTRIES N SHS - A - N53745100 17 204 SH   OTR   0 204 0
MACYS INC COM 55616P104 11 452 SH   OTR   0 452 0
MARATHON PETE CORP COM 56585A102 20 330 SH   OTR   0 330 0
MARKER THERAPEUTICS INC COM 57055L107 262 39,672 SH   OTR   0 39,672 0
MASTERCARD INC CL A 57636Q104 39 165 SH   OTR   0 165 0
MEDTRONIC PLC SHS G5960L103 11 121 SH   OTR   0 121 0
METLIFE INC COM 59156R108 22 520 SH   OTR   0 520 0
MIRATI THERAPEUTICS INC COM 60468T105 477 6,506 SH   OTR   0 6,506 0
MOMENTA PHARMACEUTICALS INC COM 60877T100 1,007 69,315 SH   OTR   0 69,315 0
MOMO INC ADR 60879B107 3 67 SH   OTR   0 225,219 0
MYOKARDIA INC COM 62857M105 253 4,859 SH   OTR   0 225,219 0
NETEASE INC SPONSORED ADR 64110W102 22 92 SH   OTR   0 92 0
NEUROCRINE BIOSCIENCES INC COM 64125C109 940 10,671 SH   OTR   0 10,671 0
NEURONETICS INC COM 64131A105 206 13,535 SH   OTR   0 13,535 0
NEXTERA ENERGY INC COM 65339F101 27 141 SH   OTR   0 141 0
NIGHTSTAR THERAPEUTICS PLC ADR 65413A101 603 23,777 SH   OTR   0 23,777 0
NXP SEMICONDUCTORS N V COM N6596X109 13 152 SH   OTR   0 152 0
OPTINOSE INC COM 68404V100 355 34,499 SH   OTR   0 34,499 0
PETROLEO BRASILEIRO SA PETRO SP ADR NON VTG 71654V101 55 3,864 SH   OTR   0 3,864 0
PRINCIPAL FINL GROUP INC COM 74251V102 17 348 SH   OTR   0 620,809 0
PRINCIPIA BIOPHARMA INC COM 74257L108 308 9,048 SH   OTR   0 620,809 0
PROLOGIS INC COM 74340W103 12 161 SH   OTR   0 161 0
PROQR THRAPEUTICS N V SHS EURO N71542109 207 14,925 SH   OTR   0 14,925 0
PROTHENA CORP PLC SHS G72800108 278 22,918 SH   OTR   0 22,918 0
PTC THERAPEUTICS INC COM 69366J200 299 7,947 SH   OTR   0 7,947 0
PUBLIC STORAGE COM 74460D109 22 102 SH   OTR   0 102 0
PUMA BIOTECHNOLOGY INC COM 74587V107 1,295 33,378 SH   OTR   0 33,378 0
RA PHARMACEUTICALS INC COM 74933V108 363 16,188 SH   OTR   0 16,188 0
REATA PHARMACEUTICALS INC CL A 75615P103 376 4,396 SH   OTR   0 1,317,938 0
REGENERON PHARMACEUTICALS COM 75886F107 850 2,071 SH   OTR   0 1,317,938 0
REGENXBIO INC COM 75901B107 335 5,841 SH   OTR   0 5,841 0
RHYTHM PHARMACEUTICALS INC COM 76243J105 260 9,468 SH   OTR   0 9,468 0
ROCKET PHARMACEUTICALS INC COM 77313F106 312 17,799 SH   OTR   0 17,799 0
SAGE THERAPEUTICS INC COM 78667J108 421 2,645 SH   OTR   0 2,645 0
SEAGATE TECHNOLOGY PLC SHS G7945M107 14 296 SH   OTR   0 12,479 0
SIGNATURE BK NEW YORK N Y COM 82669G104 13 101 SH   OTR   0 101 0
SORRENTO THERAPEUTICS INC COM NEW 83587F202 512 107,761 SH   OTR   0 107,761 0
SPARK THERAPEUTICS INC COM 84652J103 2,249 19,751 SH   OTR   0 19,751 0
SS&C TECHNOLOGIES HLDGS INC COM 78467J100 20 318 SH   OTR   0 318 0
STEMLINE THERAPEUTICS INC COM 85858C107 345 26,854 SH   OTR   0 26,854 0
SYNCHRONY FINL COM 87165B103 21 644 SH   OTR   0 644 0
TG THERAPEUTICS INC COM 88322Q108 434 53,943 SH   OTR   0 53,943 0
THERAVANCE BIOPHARMA INC COM G8807B106 649 28,612 SH   OTR   0 28,612 0
TRICIDA INC COM 89610F101 333 8,627 SH   OTR   0 8,627 0
ULTRAGENYX PHARMACEUTICAL IN COM 90400D108 1,136 16,385 SH   OTR   0 16,385 0
UNIQURE NV SHS N90064101 569 9,543 SH   OTR   0 9,543 0
UNITED THERAPEUTICS CORP DEL COM 91307C102 831 7,084 SH   OTR   0 11,750 0
UNITY BIOTECHNOLOGY INC COM 91381U101 134 16,533 SH   OTR   0 16,533 0
VEDANTA LTD SPONSORED ADR 92242Y100 1 84 SH   OTR   0 84 0
VERTEX PHARMACEUTICALS INC COM 92532F100 814 4,427 SH   OTR   0 4,427 0
VIACOM INC NEW CL B 92553P201 11 407 SH   OTR   0 407 0
VIKING THERAPEUTICS INC COM 92686J106 287 28,854 SH   OTR   0 28,854 0
VOYAGER THERAPEUTICS INC COM 92915B106 491 25,651 SH   OTR   0 25,651 0
WASTE MGMT INC DEL COM 94106L109 19 181 SH   OTR   0 181 0
WAVE LIFE SCIENCES LTD SHS Y95308105 209 5,373 SH   OTR   0 5,373 0
WEC ENERGY GROUP INC COM 92939U106 36 451 SH   OTR   0 451 0
WORKDAY INC CL A 98138H101 15 80 SH   OTR   0 80 0
XCEL ENERGY INC COM 98389B100 38 680 SH   OTR   0 680 0
XENCOR INC COM 98401F105 222 7,160 SH   OTR   0 7,160 0
YUM CHINA HLDGS INC COM 98850P109 12 278 SH   OTR   0 278 0
ZIOPHARM ONCOLOGY INC COM 98973P101 355 92,148 SH   OTR   0 92,148 0