0001567619-22-003866.txt : 20220214 0001567619-22-003866.hdr.sgml : 20220214 20220214095602 ACCESSION NUMBER: 0001567619-22-003866 CONFORMED SUBMISSION TYPE: 13F-HR PUBLIC DOCUMENT COUNT: 2 CONFORMED PERIOD OF REPORT: 20211231 FILED AS OF DATE: 20220214 DATE AS OF CHANGE: 20220214 EFFECTIVENESS DATE: 20220214 FILER: COMPANY DATA: COMPANY CONFORMED NAME: EcoR1 Capital, LLC CENTRAL INDEX KEY: 0001587114 IRS NUMBER: 000000000 STATE OF INCORPORATION: DE FISCAL YEAR END: 1231 FILING VALUES: FORM TYPE: 13F-HR SEC ACT: 1934 Act SEC FILE NUMBER: 028-16764 FILM NUMBER: 22626461 BUSINESS ADDRESS: STREET 1: 357 TEHAMA STREET #3 CITY: SAN FRANCISCO STATE: CA ZIP: 94103 BUSINESS PHONE: 415-448-6534 MAIL ADDRESS: STREET 1: 357 TEHAMA STREET #3 CITY: SAN FRANCISCO STATE: CA ZIP: 94103 13F-HR 1 primary_doc.xml 13F-HR LIVE false true false 0001587114 XXXXXXXX 12-31-2021 12-31-2021 EcoR1 Capital, LLC

357 TEHAMA STREET #3 SAN FRANCISCO CA 94103

13F HOLDINGS REPORT 028-16764 N Oleg Nodelman 415-448-6534 /s/ Oleg Nodelman San Francisco CA 02-14-2022 0 76 3138062 false INFORMATION TABLE 2 form13fInfoTable.xml 2SEVENTY BIO ORD COMMON STOCK ADDED 901384107 49134 1917063 SH SOLE 1917063 0 0 5 01 ACQUISITION CORP COM CL A 33836P105 1970 200000 SH SOLE 200000 0 0 AC IMMUNE SA SHS H00263105 3710 749585 SH SOLE 749585 0 0 ACADIA PHARMACEUTICALS INC COM 004225108 71434 3060593 SH SOLE 3060593 0 0 ADVERUM BIOTECHNOLOGIES INC COM 00773U108 1842 1046700 SH SOLE 1046700 0 0 AKOUOS INC COM 00973J101 16796 1975984 SH SOLE 1975984 0 0 ALECTOR INC COM 014442107 103146 4994970 SH SOLE 4994970 0 0 ALIGOS THERAPEUTICS INC COM 01626L105 1081 91044 SH SOLE 91044 0 0 ALNYLAM PHARMACEUTICALS INC COM 02043Q107 16644 98146 SH SOLE 98146 0 0 ANAPTYSBIO INC COM 032724106 261356 7521024 SH SOLE 7521024 0 0 APELLIS PHARMACEUTICALS INC COM 03753U106 190722 4033882 SH SOLE 4033882 0 0 APPLIED MOLECULAR TRANS INC COM 03824M109 5592 400000 SH SOLE 400000 0 0 ARCUS BIOSCIENCES INC COM 03969F109 223530 5523358 SH SOLE 5523358 0 0 ARVINAS INC COM 04335A105 10703 130300 SH SOLE 130300 0 0 ARYA SCIENCES ACQU CORP IV CL A G31659108 1487 150000 SH SOLE 150000 0 0 ATEA PHARMACEUTICALS INC COM 04683R106 48063 5376134 SH SOLE 5376134 0 0 AVIDITY BIOSCIENCES INC COM 05370A108 65593 2759505 SH SOLE 2759505 0 0 BCLS ACQUISITION CORP COM CL A G0904B105 1960 200000 SH SOLE 200000 0 0 BOLT BIOTHERAPEUTICS INC COM 097702104 735 150000 SH SOLE 150000 0 0 C4 THERAPEUTICS INC COM STK 12529R107 6440 200000 SH SOLE 200000 0 0 CAREMAX INC *W EXP 06/08/202 14171W111 768 100000 SH SOLE 100000 0 0 CARIBOU BIOSCIENCES INC COM 142038108 1132 75000 SH SOLE 75000 0 0 CENTESSA PHARMACEUTICALS PLC SPONSORED ADS 152309100 9933 882176 SH SOLE 882176 0 0 CRINETICS PHARMACEUTICALS IN COM 22663K107 16767 590169 SH SOLE 590169 0 0 CRISPR THERAPEUTICS AG NAMEN AKT H17182108 81652 1077483 SH SOLE 1077483 0 0 DESIGN THERAPEUTICS INC COM 25056L103 46096 2152997 SH SOLE 2152997 0 0 DYNE THERAPEUTICS INC COM 26818M108 2556 215000 SH SOLE 215000 0 0 EDGEWISE THERAPEUTICS INC COM 28036F105 19546 1279175 SH SOLE 1279175 0 0 ERASCA INC COM 29479A108 10906 700000 SH SOLE 700000 0 0 EUCRATES BIOMEDICAL ACQU COR SHS G3141W106 1952 200000 SH SOLE 200000 0 0 EUCRATES BIOMEDICAL ACQU COR *W EXP 10/23/202 G3141W122 651 66666 SH SOLE 66666 0 0 FRAZIER LIFESCIENCES ACQU CO *W EXP 11/30/202 G3710A113 650 66665 SH SOLE 66665 0 0 FRAZIER LIFESCIENCES ACQU CO SHS G3710A105 5729 587615 SH SOLE 587615 0 0 GALAPAGOS NV SPON ADR 36315X101 122631 2224403 SH SOLE 2224403 0 0 GRAPHITE BIO INC COM 38870X104 8563 688900 SH SOLE 688900 0 0 GRITSTONE BIO INC COM 39868T105 77317 6012232 SH SOLE 6012232 0 0 GRITSTONE BIO INC COM 39868T105 3948 307000 SH Call SOLE 307000 0 0 HALOZYME THERAPEUTICS INC COM 40637H109 15762 392000 SH SOLE 392000 0 0 HEALTH SCIENCES ACQ CORP 2 ORD SHS G4411D109 4032 400000 SH SOLE 400000 0 0 HELIX ACQUISITION CORP COM CL A G4444C102 1978 200000 SH SOLE 200000 0 0 IMMUNOVANT INC COM 45258J102 9720 1140819 SH SOLE 1140819 0 0 ITEOS THERAPEUTICS INC COM 46565G104 60675 1303157 SH SOLE 1303157 0 0 JANUX THERAPEUTICS INC COM 47103J105 27858 1411975 SH SOLE 1411975 0 0 JIYA ACQUISITION CORP COM CL A 47760M102 4885 500000 SH SOLE 500000 0 0 KINNATE BIOPHARMA INC COM 49705R105 3101 175000 SH SOLE 175000 0 0 KRONOS BIO INC COM 50107A104 5264 387357 SH SOLE 387357 0 0 KURA ONCOLOGY INC COM 50127T109 52142 3724437 SH SOLE 3724437 0 0 LEGEND BIOTECH CORP SPONSORED ADS 52490G102 14337 307594 SH SOLE 307594 0 0 MONTE ROSA THERAPEUTICS INC COM 61225M102 768 37593 SH SOLE 37593 0 0 MORPHIC HLDG INC COM 61775R105 187225 3951566 SH SOLE 3951566 0 0 NEOLEUKIN THERAPEUTICS INC COM 64049K104 4148 860619 SH SOLE 860619 0 0 NURIX THERAPEUTICS INC COM 67080M103 8961 309540 SH SOLE 309540 0 0 NUVATION BIO INC *W EXP 07/07/202 67080N119 8188 963333 SH SOLE 963333 0 0 NUVATION BIO INC COM CL A 67080N101 118121 13896543 SH SOLE 13896543 0 0 OMEGA ALPHA SPAC CL A G6749V107 489 50000 SH SOLE 50000 0 0 ORIC PHARMACEUTICALS INC COM 68622P109 50993 3468944 SH SOLE 3468944 0 0 OVID THERAPEUTICS INC COM 690469101 19524 6082200 SH SOLE 6082200 0 0 PARDES BIOSCIENCES ORD COM ADDED 69945Q105 26145 1597139 SH SOLE 1597139 0 0 PMV PHARMACEUTICALS INC COM 69353Y103 1155 50000 SH SOLE 50000 0 0 PROTAGONIST THERAPEUTICS INC COM 74366E102 90278 2639706 SH SOLE 2639706 0 0 PROTHENA CORP PLC SHS G72800108 557443 11284280 SH SOLE 11284280 0 0 RELAY THERAPEUTICS INC COM 75943R102 54636 1779084 SH SOLE 1779084 0 0 REPARE THERAPEUTICS INC COM 760273102 1055 50000 SH SOLE 50000 0 0 SAGE THERAPEUTICS INC COM 78667J108 40015 940636 SH SOLE 940636 0 0 SILVERBACK THERAPEUTICS INC COM 82835W108 7060 1060010 SH SOLE 1060010 0 0 SOLID BIOSCIENCES INC COM 83422E105 16105 9202702 SH SOLE 9202702 0 0 SURROZEN INC COM 86889P117 429 66665 SH SOLE 66665 0 0 TANGO THERAPEUTICS INC COM 87583X109 14222 1300000 SH SOLE 1300000 0 0 TURMERIC ACQUISITION CORP CL A G9127T108 982 100000 SH SOLE 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