The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
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COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP FIGI (to the nearest dollar) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
ACADIA PHARMACEUTICALS INC COM 004225108   110,782,447 5,991,479 SH   SOLE   5,991,479 0 0
ADAPTIMMUNE THERAPEUTICS PLC SPONDS ADR 00653A107   43,298,431 27,404,070 SH   SOLE   27,404,070 0 0
ALECTOR INC COM 014442107   24,420,419 4,056,548 SH   SOLE   4,056,548 0 0
ALIGOS THERAPEUTICS INC COM 01626L105   6,261,679 6,389,468 SH   SOLE   6,389,468 0 0
ALLOVIR INC COM 019818103   8,526,282 11,294,585 SH   SOLE   11,294,585 0 0
ALPINE IMMUNE SCIENCES INC COM 02083G100   39,640 1,000 SH   SOLE   1,000 0 0
ANAPTYSBIO INC COM 032724106   169,373,460 7,521,024 SH   SOLE   7,521,024 0 0
APELLIS PHARMACEUTICALS INC COM 03753U106   667,589,442 11,357,425 SH   SOLE   11,357,425 0 0
ARCUTIS BIOTHERAPEUTICS INC COM 03969K108   4,955,000 500,000 SH   SOLE   500,000 0 0
ARVINAS INC COM 04335A105   277,669,548 6,726,491 SH   SOLE   6,726,491 0 0
ATARA BIOTHERAPEUTICS INC COM 046513107   7,055,928 10,167,043 SH   SOLE   10,167,043 0 0
ATEA PHARMACEUTICALS INC COM 04683R106   24,829,278 6,145,861 SH   SOLE   6,145,861 0 0
AVIDITY BIOSCIENCES INC COM 05370A108   19,333,340 757,576 SH   SOLE   757,576 0 0
CAREMAX INC *W EXP 06/08/202 14171W111   482,000 100,000 SH   SOLE   100,000 0 0
CELLDEX THERAPEUTICS INC COM NEW 15117B202   27,280,500 650,000 SH   SOLE   650,000 0 0
CENTESSA PHARMACEUTICALS PLC SPONSORED ADS 152309100   63,492,203 5,618,779 SH   SOLE   5,618,779 0 0
CRINETICS PHARMACEUTICALS IN COM 22663K107   194,513,104 4,155,375 SH   SOLE   4,155,375 0 0
CRISPR THERAPEUTICS AG NAMEN AKT H17182108   94,693,052 1,389,276 SH   SOLE   1,389,276 0 0
DYNE THERAPEUTICS INC COM 26818M108   12,123,637 427,039 SH   SOLE   427,039 0 0
EDGEWISE THERAPEUTICS INC COM 28036F105   22,807,022 1,250,385 SH   SOLE   1,250,385 0 0
GALAPAGOS NV SPON ADR 36315X101   185,351,830 5,756,268 SH   SOLE   5,756,268 0 0
GENERATION BIO CO COM 37148K100   8,330,749 2,046,867 SH   SOLE   2,046,867 0 0
GOSSAMER BIO INC COM 38341P102   10,850,577 9,195,404 SH   SOLE   9,195,404 0 0
HOOKIPA PHARMA INC COM 43906K100   3,271,657 4,595,024 SH   SOLE   4,595,024 0 0
IMMUNOME INC COM 45257U108   95,743,962 3,879,415 SH   SOLE   3,879,415 0 0
ITEOS THERAPEUTICS INC COM 46565G104   27,269,756 1,999,249 SH   SOLE   1,999,249 0 0
JAZZ PHARMACEUTICALS PLC SHS USD G50871105   122,100,100 1,013,952 SH   SOLE   1,013,952 0 0
KEROS THERAPEUTICS INC COM 492327101   12,412,500 187,500 SH   SOLE   187,500 0 0
KODIAK SCIENCES INC COM 50015M109   8,487,536 1,613,600 SH   SOLE   1,613,600 0 0
KODIAK SCIENCES INC COM 50015M109   268,786 51,100 SH Call SOLE   51,100 0 0
KURA ONCOLOGY INC COM 50127T109   123,860,558 5,806,871 SH   SOLE   5,806,871 0 0
KURA ONCOLOGY INC COM 50127T109   14,931,000 700,000 SH Call SOLE   700,000 0 0
KYVERNA THERAPEUTICS INC COM ADDED 501976104   11,178,000 450,000 SH   SOLE   450,000 0 0
LENZ THERAPEUTICS INC COM ADDED 52635N103   27,237,553 1,219,774 SH   SOLE   1,219,774 0 0
MADRIGAL PHARMACEUTICALS INC COM 558868105   20,028,000 75,000 SH   SOLE   75,000 0 0
MERSANA THERAPEUTICS INC COM 59045L106   86,753,802 19,364,688 SH   SOLE   19,364,688 0 0
MORPHIC HLDG INC COM 61775R105   83,930,317 2,384,384 SH   SOLE   2,384,384 0 0
NEUMORA THERAPEUTICS INC. COM 640979100   28,482,438 2,071,450 SH   SOLE   2,071,450 0 0
NEUROGENE INC COM 64135M105   64,711,308 1,271,342 SH   SOLE   1,271,342 0 0
NKARTA INC COM 65487U108   21,620,000 2,000,000 SH   SOLE   2,000,000 0 0
NUVATION BIO INC *W EXP 07/07/202 67080N119   3,506,532 963,333 SH   SOLE   963,333 0 0
NUVATION BIO INC COM CL A 67080N101   69,923,101 19,209,643 SH   SOLE   19,209,643 0 0
ORIC PHARMACEUTICALS INC COM 68622P109   46,998,435 3,418,068 SH   SOLE   3,418,068 0 0
OVID THERAPEUTICS INC COM 690469101   18,658,070 6,117,400 SH   SOLE   6,117,400 0 0
PHARVARIS N V COM N69605108   20,799,000 900,000 SH   SOLE   900,000 0 0
PMV PHARMACEUTICALS INC COM 69353Y103   963,694 566,879 SH   SOLE   566,879 0 0
PRIME MEDICINE INC COM 74168J101   4,900,000 700,000 SH   SOLE   700,000 0 0
PROQR THRAPEUTICS N V SHS EURO N71542109   6,604,889 2,884,357 SH   SOLE   2,884,357 0 0
PROTHENA CORP PLC SHS G72800108   286,942,616 11,584,280 SH   SOLE   11,584,280 0 0
SAREPTA THERAPEUTICS INC COM 803607100   248,541,839 1,919,835 SH   SOLE   1,919,835 0 0
SURROZEN INC *W EXP 08/01/203 86889P117   1,047,307 66,665 SH   SOLE   66,665 0 0
TANGO THERAPEUTICS INC COM 87583X109   105,846,044 13,330,736 SH   SOLE   13,330,736 0 0
THIRD HARMONIC BIO INC COM 88427A107   30,042,271 3,182,444 SH   SOLE   3,182,444 0 0
TSCAN THERAPEUTICS INC COM 89854M101   39,700,000 5,000,000 SH   SOLE   5,000,000 0 0
VAXCYTE INC COM 92243G108   20,493,000 300,000 SH   SOLE   300,000 0 0
VERVE THERAPEUTICS INC COM 92539P101   16,600,000 1,250,000 SH   SOLE   1,250,000 0 0
VOYAGER THERAPEUTICS INC COM 92915B106   36,472,353 3,917,546 SH   SOLE   3,917,546 0 0
XENCOR INC COM 98401F105   117,962,106 5,330,416 SH   SOLE   5,330,416 0 0
ZYMEWORKS INC COM 98985Y108   141,362,216 13,437,473 SH   SOLE   13,437,473 0 0