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Preferred Stock - Series A Redeemable Convertible Preferred Stock (Details) - USD ($)
1 Months Ended 6 Months Ended 12 Months Ended
Apr. 13, 2021
Sep. 30, 2020
Mar. 31, 2018
Jun. 30, 2021
Dec. 31, 2020
Dec. 31, 2021
Oct. 31, 2020
Jul. 31, 2019
Shares Authorized           1,021,165    
Number of shares issued for each convertible preferred stock               166
Carrying amount in excess of fair value amount   $ 150,000     $ 2,500,000      
Maximum                
Product revenue       $ 22,000,000.0        
Average VWAP of common stock for the 30 days prior to Measurement Date       $ 315.00        
Series C perpetual preferred stock                
Shares Authorized         1,011,000 1,011,000    
Shares issued (in shares)   842,500            
Deemed dividend attributable         $ 2,521,000      
Series D perpetual preferred stock                
Shares issued (in shares)   842,500            
Convertible preferred stock, shares outstanding         0 0    
Series A                
Shares Authorized     5,524,926          
Convertible preferred stock, shares outstanding         0      
Series A convertible participating preferred stock                
Redemption price per share           $ 2.3057    
Deemed dividend attributable         $ 1,300,000      
Sagard Capital Partners, L.P. | Series C perpetual preferred stock                
Preferred stock, par value (in dollars per share)     $ 0.0001          
Sagard Capital Partners, L.P. | Series A convertible participating preferred stock                
Number of shares issued for each convertible preferred stock     157,855          
Effective conversion price     $ 582.75          
Maximum period from date of issuance     1 year          
Iliad                
Shares issued (in shares) 588,235              
Iliad | Series C perpetual preferred stock                
Preferred stock, par value (in dollars per share)   $ 0.0001         $ 0.0001  
Gross proceeds from the issuance of common stock   $ 2,300,000            
Number of shares issued for each convertible preferred stock   842,500            
Second Amendment to Note Purchase Agreement and Notes | Sagard Capital Partners, L.P. | Series A convertible participating preferred stock | Private placement                
Gross proceeds from the issuance of common stock     $ 9,200,000          
Amount of shares issued     $ 9,000,000.0