Commitments and Contingencies - Commitments (Details)					1 Months Ended	12 Months Ended
	Dec. 24, 2021 USD ($)	Apr. 06, 2021 USD ($) ft²	Aug. 31, 2020 USD ($) ft²	Aug. 28, 2018 USD ($) ft² shares	Dec. 31, 2021 USD ($)	Dec. 31, 2021 USD ($)	Dec. 31, 2020 USD ($)
Commitments and Contingencies
Standby letter of credit received as collateral				$ 475,000
Term				5 years
Warrants to purchase (in shares) | shares				9,580
Lease expense under non-cancelable operating lease					$ 21,000
Monthly base rent	$ 21,000
Cash paid for operating lease liabilities recognized under operating cash flows						$ 105,260,000	$ 357,079,000
Addition to right-of-use asset obtained from new operating liabilities						1,087,000	0
Lease modification						91,243	0
Minimum
Commitments and Contingencies
Lease expense under non-cancelable operating lease						38,000
General and administrative expense
Commitments and Contingencies
Lease expense under non-cancelable operating lease						75,000	45,000
Lease cost						144,000
Office lease extension agreement
Commitments and Contingencies
Area (in square feet) | ft²				6,311
Office space sub lease
Commitments and Contingencies
Area (in square feet) | ft²		10,526	5,263
Sub lease rent			$ 15,000
Remaining commitment					$ 0	0
Extension period		3 years
Lease term		3 years
Monthly base rent for first twelve months		$ 42,000
Monthly base rent for subsequent twelve months		43,000
Monthly base rent for final months		$ 45,000
Short-term office lease in Milan, Italy | General and administrative expense
Commitments and Contingencies
Lease expense under non-cancelable operating lease						$ 23,000	$ 0