Stock Based Compensation (Tables)

12 Months Ended

Dec. 31, 2021

Stock Based Compensation

Summary of incentive plan activity

				Weighted		Weighted Average
	Shares	Stock		Average		Remaining	Aggregate
	Available	Options	RSUs	Stock Option		Contractual Life	Intrinsic
(in thousands, except share and per share data)	for Grant	Outstanding	Outstanding	Exercise Price		(Years)	Value*
Outstanding at December 31, 2020	198,866	1,523,790	1,871	$	12.68	8.71	$	364
Additional shares authorized	1,900,421	—	—		—			—
Options granted	(1,016,044)	1,016,044	—		5.41			—
Options exercised	—	(3,147)	—		1.34			—
Options canceled	33,612	(33,612)	—		30.47			—
RSUs granted	(485,585)	—	485,585		—			—
Outstanding at December 31, 2021	631,270	2,503,075	487,456	$	9.44	8.35	$	3
Exercisable at December 31, 2021		1,431,658		$	12.92	7.84	$	2
Vested and expected to vest at December 31, 2021		2,362,310		$	9.70	8.30	$	3

*Fair market value of Jaguar stock on December 31, 2021 was $1.04 per share.

Summary of stock-based compensation expense

	Year Ended
	December 31,
(in thousands)	2021		2020
Research and development expense	$	1,319	$	749
Sales and marketing expense		319		220
General and administrative expense		2,336		1,855
Total	$	3,974	$	2,824

Employee stock options

Stock Based Compensation

Schedule of estimated grant-date fair value of stock options calculated using the Black-Scholes option-pricing model

	Year Ended
	December 31,
	2021	2020
Volatility	163.8 - 164.0 %	150.1 - 167.9 %
Expected term (years)	5.0	5.0
Risk-free interest rate	0.5 - 1.2 %	0.3 - 0.5 %
Expected dividend yield	—	—