Collaboration Agreements (Details) - USD ($) $ in Millions		1 Months Ended	6 Months Ended		9 Months Ended	12 Months Ended
	May 15, 2015	May 31, 2015	Dec. 31, 2015	Dec. 27, 2014	Mar. 29, 2014	Dec. 31, 2016	Jun. 27, 2015	Jun. 28, 2014
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]
Research and development			$ 88.2	$ 89.8		$ 184.0	$ 187.8	$ 152.5
Potential contingent milestone payments							30.0
Royalty revenue, percent of net sales					6.50%
Minimum
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]
Potential contingent milestone payments					$ 10.0
Maximum
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]
Potential contingent milestone payments					$ 15.0
May 2015 agreement [Member] | Minimum
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]
Potential contingent milestone payments	$ 78.0					126.0
May 2015 agreement [Member] | Maximum
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]
Potential contingent milestone payments	$ 105.0					$ 174.0
Biotech [Member]
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]
Research and development							10.0
Potential contingent milestone payments							50.0
Phase three [Member] | Biotech [Member]
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]
Research and development							5.0
Final phase [Member] | Biotech [Member]
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]
Research and development							$ 10.0
Contractual arrangement [Member]
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]
Research and development		$ 18.0