Stock-Based Compensation (Tables)

3 Months Ended

Mar. 31, 2023

Share-Based Payment Arrangement [Abstract]

Summary of Stock Option Activity

A summary of stock option activity during the three months ended March 31, 2023 is as follows:

	Number of Units Outstanding			Weighted Average Strike Price per Unit		Weighted Average Remaining Contractual Term (in years)		Aggregate Intrinsic Value (in thousands)
Outstanding at December 31, 2022		8,402,626		$	3.52		8.6	$	—
Granted		3,550,000		$	0.57
Exercised		—		$	—
Forfeited		(363,272	)	$	1.69
Expired		(14,351	)	$	7.27
Outstanding at March 31, 2023		11,575,003		$	2.65		8.9	$	—
Options vested and expected to vest at March 31, 2023		11,575,003		$	2.65		8.9	$	—
Options vested and exercisable at March 31, 2023		3,373,505		$	4.69		7.8	$	—

Summary of Restricted Stock Unit Activity

A summary of RSU activity during the three months ended March 31, 2023 is as follows:

	Number of Units Outstanding			Weighted Average Grant Date Fair Value (per RSU)
Outstanding at December 31, 2022		326,364		$	2.75
Granted		12,100		$	0.56
Vested		(9,750	)	$	1.61
Forfeited		(27,500	)	$	2.01
Outstanding at March 31, 2023		301,214		$	2.76

Components of Stock-based Compensation Expense

The following table summarizes the components of stock-based compensation expense recorded in the Company’s statement of operations and comprehensive loss (in thousands):

	Three Months Ended March 31,
	2023		2022
Research and development	$	231	$	575
Selling, general and administrative		952		970
Total stock-based compensation	$	1,183	$	1,545