<SEC-DOCUMENT>0001583648-20-000015-index.html : 20200313
<SEC-HEADER>0001583648-20-000015.hdr.sgml : 20200313
<ACCEPTANCE-DATETIME>20200313172249
ACCESSION NUMBER:		0001583648-20-000015
CONFORMED SUBMISSION TYPE:	10-K
PUBLIC DOCUMENT COUNT:		160
CONFORMED PERIOD OF REPORT:	20191231
FILED AS OF DATE:		20200313
DATE AS OF CHANGE:		20200313

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			PIERIS PHARMACEUTICALS, INC.
		CENTRAL INDEX KEY:			0001583648
		STANDARD INDUSTRIAL CLASSIFICATION:	SERVICES-COMMERCIAL PHYSICAL & BIOLOGICAL RESEARCH [8731]
		IRS NUMBER:				300784346
		STATE OF INCORPORATION:			NV
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		10-K
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-37471
		FILM NUMBER:		20714012

	BUSINESS ADDRESS:	
		STREET 1:		255 STATE STREET
		STREET 2:		9TH FLOOR
		CITY:			BOSTON
		STATE:			MA
		ZIP:			02109
		BUSINESS PHONE:		857-246-8998

	MAIL ADDRESS:	
		STREET 1:		255 STATE STREET
		STREET 2:		9TH FLOOR
		CITY:			BOSTON
		STATE:			MA
		ZIP:			02109

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	Marika Inc.
		DATE OF NAME CHANGE:	20130805
</SEC-HEADER>
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<FILENAME>pirs12-31x201910xk.htm
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Document 1 - file: pirs12-31x201910xk.htm
</DOCUMENT> <DOCUMENT> <TYPE>EX-4.3 <SEQUENCE>2 <FILENAME>pirs12312019ex-43.htm <DESCRIPTION>EXHIBIT 4.3 <TEXT> Document 2 - file: pirs12312019ex-43.htm
</DOCUMENT> <DOCUMENT> <TYPE>EX-10.16 <SEQUENCE>3 <FILENAME>pirs12312019ex1016.htm <DESCRIPTION>EXHIBIT 10.16 <TEXT> Document 3 - file: pirs12312019ex1016.htm
</DOCUMENT> <DOCUMENT> <TYPE>EX-10.25 <SEQUENCE>4 <FILENAME>pirs12312019ex1025.htm <DESCRIPTION>EXHIBIT 10.25 <TEXT> Document 4 - file: pirs12312019ex1025.htm
</DOCUMENT> <DOCUMENT> <TYPE>EX-10.26 <SEQUENCE>5 <FILENAME>pirs12312019ex1026.htm <DESCRIPTION>EXHIBIT 10.26 <TEXT> Document 5 - file: pirs12312019ex1026.htm
</DOCUMENT> <DOCUMENT> <TYPE>EX-10.31 <SEQUENCE>6 <FILENAME>pirs12312019exh1031.htm <DESCRIPTION>EXHIBIT 10.31 <TEXT> Document 6 - file: pirs12312019exh1031.htm
</DOCUMENT> <DOCUMENT> <TYPE>EX-10.32 <SEQUENCE>7 <FILENAME>pirs12312019exh1032.htm <DESCRIPTION>EXHIBIT 10.32 <TEXT> Document 7 - file: pirs12312019exh1032.htm
</DOCUMENT> <DOCUMENT> <TYPE>EX-14.1 <SEQUENCE>8 <FILENAME>pirs12312019ex141.htm <DESCRIPTION>EXHIBIT 14.1 <TEXT> Document 8 - file: pirs12312019ex141.htm
</DOCUMENT> <DOCUMENT> <TYPE>EX-21.1 <SEQUENCE>9 <FILENAME>pirs12-31x2019ex211.htm <DESCRIPTION>EXHIBIT 21.1 <TEXT> Document 9 - file: pirs12-31x2019ex211.htm
</DOCUMENT> <DOCUMENT> <TYPE>EX-23.1 <SEQUENCE>10 <FILENAME>pirs12-31x2019ex231.htm <DESCRIPTION>EXHIBIT 23.1 <TEXT> Document 10 - file: pirs12-31x2019ex231.htm
</DOCUMENT> <DOCUMENT> <TYPE>EX-31.1 <SEQUENCE>11 <FILENAME>pirs12-31x2019ex311.htm <DESCRIPTION>EXHIBIT 31.1 <TEXT> Document 11 - file: pirs12-31x2019ex311.htm
</DOCUMENT> <DOCUMENT> <TYPE>EX-31.2 <SEQUENCE>12 <FILENAME>pirs12-31x2019ex312.htm <DESCRIPTION>EXHIBIT 31.2 <TEXT> Document 12 - file: pirs12-31x2019ex312.htm
</DOCUMENT> <DOCUMENT> <TYPE>EX-32.1 <SEQUENCE>13 <FILENAME>pirs12-31x2019ex321.htm <DESCRIPTION>EXHIBIT 32.1 <TEXT> Document 13 - file: pirs12-31x2019ex321.htm
</DOCUMENT> <DOCUMENT> <TYPE>EX-32.2 <SEQUENCE>14 <FILENAME>pirs12-31x2019ex322.htm <DESCRIPTION>EXHIBIT 32.2 <TEXT> Document 14 - file: pirs12-31x2019ex322.htm
</DOCUMENT> <DOCUMENT> <TYPE>EX-101.INS <SEQUENCE>15 <FILENAME>pirs-20191231.xml <DESCRIPTION>XBRL INSTANCE DOCUMENT <TEXT> Document 15 - file: pirs-20191231.xml
</DOCUMENT> <DOCUMENT> <TYPE>EX-101.SCH <SEQUENCE>16 <FILENAME>pirs-20191231.xsd <DESCRIPTION>XBRL TAXONOMY EXTENSION SCHEMA DOCUMENT <TEXT> Document 16 - file: pirs-20191231.xsd
</DOCUMENT> <DOCUMENT> <TYPE>EX-101.CAL <SEQUENCE>17 <FILENAME>pirs-20191231_cal.xml <DESCRIPTION>XBRL TAXONOMY EXTENSION CALCULATION LINKBASE DOCUMENT <TEXT> Document 17 - file: pirs-20191231_cal.xml
</DOCUMENT> <DOCUMENT> <TYPE>EX-101.DEF <SEQUENCE>18 <FILENAME>pirs-20191231_def.xml <DESCRIPTION>XBRL TAXONOMY EXTENSION DEFINITION LINKBASE DOCUMENT <TEXT> Document 18 - file: pirs-20191231_def.xml
</DOCUMENT> <DOCUMENT> <TYPE>EX-101.LAB <SEQUENCE>19 <FILENAME>pirs-20191231_lab.xml <DESCRIPTION>XBRL TAXONOMY EXTENSION LABEL LINKBASE DOCUMENT <TEXT> Document 19 - file: pirs-20191231_lab.xml
</DOCUMENT> <DOCUMENT> <TYPE>EX-101.PRE <SEQUENCE>20 <FILENAME>pirs-20191231_pre.xml <DESCRIPTION>XBRL TAXONOMY EXTENSION PRESENTATION LINKBASE DOCUMENT <TEXT> Document 20 - file: pirs-20191231_pre.xml
</DOCUMENT> <DOCUMENT> <TYPE>GRAPHIC <SEQUENCE>21 <FILENAME>a344charta01.jpg <TEXT> Document 21 - file: a344charta01.jpg
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</DOCUMENT> <DOCUMENT> <TYPE>GRAPHIC <SEQUENCE>23 <FILENAME>g325265g32v61.jpg <TEXT> Document 23 - file: g325265g32v61.jpg
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</DOCUMENT> <DOCUMENT> <TYPE>GRAPHIC <SEQUENCE>28 <FILENAME>g325265g74z83.jpg <TEXT> Document 28 - file: g325265g74z83.jpg
</DOCUMENT> <DOCUMENT> <TYPE>GRAPHIC <SEQUENCE>29 <FILENAME>pirs12312019ex141001.jpg <TEXT> Document 29 - file: pirs12312019ex141001.jpg
</DOCUMENT> <DOCUMENT> <TYPE>GRAPHIC <SEQUENCE>30 <FILENAME>pirs12312019ex141002.jpg <TEXT> Document 30 - file: pirs12312019ex141002.jpg
</DOCUMENT> <DOCUMENT> <TYPE>GRAPHIC <SEQUENCE>31 <FILENAME>pirs12312019ex141003.jpg <TEXT> Document 31 - file: pirs12312019ex141003.jpg
</DOCUMENT> <DOCUMENT> <TYPE>GRAPHIC <SEQUENCE>32 <FILENAME>pirs12312019ex141004.jpg <TEXT> Document 32 - file: pirs12312019ex141004.jpg
</DOCUMENT> <DOCUMENT> <TYPE>GRAPHIC <SEQUENCE>33 <FILENAME>pirs12312019ex141005.jpg <TEXT> Document 33 - file: pirs12312019ex141005.jpg
</DOCUMENT> <DOCUMENT> <TYPE>GRAPHIC <SEQUENCE>34 <FILENAME>pirs12312019ex141006.jpg <TEXT> Document 34 - file: pirs12312019ex141006.jpg
</DOCUMENT> <DOCUMENT> <TYPE>GRAPHIC <SEQUENCE>35 <FILENAME>pirs12312019ex141007.jpg <TEXT> Document 35 - file: pirs12312019ex141007.jpg
</DOCUMENT> <DOCUMENT> <TYPE>GRAPHIC <SEQUENCE>36 <FILENAME>pirs12312019ex141008.jpg <TEXT> Document 36 - file: pirs12312019ex141008.jpg
</DOCUMENT> <DOCUMENT> <TYPE>GRAPHIC <SEQUENCE>37 <FILENAME>pirs12312019ex141009.jpg <TEXT> Document 37 - file: pirs12312019ex141009.jpg
</DOCUMENT> <DOCUMENT> <TYPE>GRAPHIC <SEQUENCE>38 <FILENAME>pirs12312019ex141010.jpg <TEXT> Document 38 - file: pirs12312019ex141010.jpg
</DOCUMENT> <DOCUMENT> <TYPE>GRAPHIC <SEQUENCE>39 <FILENAME>pirs12312019ex141011.jpg <TEXT> Document 39 - file: pirs12312019ex141011.jpg
</DOCUMENT> <DOCUMENT> <TYPE>GRAPHIC <SEQUENCE>40 <FILENAME>pirs12312019ex141012.jpg <TEXT> Document 40 - file: pirs12312019ex141012.jpg
</DOCUMENT> <DOCUMENT> <TYPE>GRAPHIC <SEQUENCE>41 <FILENAME>pirs12312019ex141013.jpg <TEXT> Document 41 - file: pirs12312019ex141013.jpg
</DOCUMENT> <DOCUMENT> <TYPE>GRAPHIC <SEQUENCE>42 <FILENAME>pirs12312019ex141014.jpg <TEXT> Document 42 - file: pirs12312019ex141014.jpg
</DOCUMENT> <DOCUMENT> <TYPE>GRAPHIC <SEQUENCE>43 <FILENAME>pirs12312019ex141015.jpg <TEXT> Document 43 - file: pirs12312019ex141015.jpg
</DOCUMENT> <DOCUMENT> <TYPE>GRAPHIC <SEQUENCE>44 <FILENAME>pirs12312019ex141016.jpg <TEXT> Document 44 - file: pirs12312019ex141016.jpg
</DOCUMENT> <DOCUMENT> <TYPE>GRAPHIC <SEQUENCE>45 <FILENAME>pirs12312019ex141017.jpg <TEXT> Document 45 - file: pirs12312019ex141017.jpg
</DOCUMENT> <DOCUMENT> <TYPE>GRAPHIC <SEQUENCE>46 <FILENAME>pirs12312019ex141018.jpg <TEXT> Document 46 - file: pirs12312019ex141018.jpg
</DOCUMENT> <DOCUMENT> <TYPE>GRAPHIC <SEQUENCE>47 <FILENAME>pirs12312019ex141019.jpg <TEXT> Document 47 - file: pirs12312019ex141019.jpg
</DOCUMENT> <DOCUMENT> <TYPE>GRAPHIC <SEQUENCE>48 <FILENAME>pirs12312019ex141020.jpg <TEXT> Document 48 - file: pirs12312019ex141020.jpg
</DOCUMENT> <DOCUMENT> <TYPE>GRAPHIC <SEQUENCE>49 <FILENAME>pirs12312019ex141021.jpg <TEXT> Document 49 - file: pirs12312019ex141021.jpg
</DOCUMENT> <DOCUMENT> <TYPE>GRAPHIC <SEQUENCE>50 <FILENAME>pirs12312019ex141022.jpg <TEXT> Document 50 - file: pirs12312019ex141022.jpg
</DOCUMENT> <DOCUMENT> <TYPE>GRAPHIC <SEQUENCE>51 <FILENAME>pirs12312019ex1016001.jpg <TEXT> Document 51 - file: pirs12312019ex1016001.jpg
</DOCUMENT> <DOCUMENT> <TYPE>GRAPHIC <SEQUENCE>52 <FILENAME>pirs12312019ex1016002.jpg <TEXT> Document 52 - file: pirs12312019ex1016002.jpg
</DOCUMENT> <DOCUMENT> <TYPE>GRAPHIC <SEQUENCE>53 <FILENAME>pirs12312019ex1016003.jpg <TEXT> Document 53 - file: pirs12312019ex1016003.jpg
</DOCUMENT> <DOCUMENT> <TYPE>GRAPHIC <SEQUENCE>54 <FILENAME>pirs12312019ex1016004.jpg <TEXT> Document 54 - file: pirs12312019ex1016004.jpg
</DOCUMENT> <DOCUMENT> <TYPE>GRAPHIC <SEQUENCE>55 <FILENAME>pirs12312019ex1016005.jpg <TEXT> Document 55 - file: pirs12312019ex1016005.jpg
</DOCUMENT> <DOCUMENT> <TYPE>GRAPHIC <SEQUENCE>56 <FILENAME>pirs12312019ex1016006.jpg <TEXT> Document 56 - file: pirs12312019ex1016006.jpg
</DOCUMENT> <DOCUMENT> <TYPE>GRAPHIC <SEQUENCE>57 <FILENAME>pirs12312019ex1016007.jpg <TEXT> Document 57 - file: pirs12312019ex1016007.jpg
</DOCUMENT> <DOCUMENT> <TYPE>GRAPHIC <SEQUENCE>58 <FILENAME>pirs12312019ex1025001.jpg <TEXT> Document 58 - file: pirs12312019ex1025001.jpg
</DOCUMENT> <DOCUMENT> <TYPE>GRAPHIC <SEQUENCE>59 <FILENAME>pirs12312019ex1025002.jpg <TEXT> Document 59 - file: pirs12312019ex1025002.jpg
</DOCUMENT> <DOCUMENT> <TYPE>GRAPHIC <SEQUENCE>60 <FILENAME>pirs12312019ex1025003.jpg <TEXT> Document 60 - file: pirs12312019ex1025003.jpg
</DOCUMENT> <DOCUMENT> <TYPE>GRAPHIC <SEQUENCE>61 <FILENAME>pirs12312019ex1025004.jpg <TEXT> Document 61 - file: pirs12312019ex1025004.jpg
</DOCUMENT> <DOCUMENT> <TYPE>GRAPHIC <SEQUENCE>62 <FILENAME>pirs12312019ex1025005.jpg <TEXT> Document 62 - file: pirs12312019ex1025005.jpg
</DOCUMENT> <DOCUMENT> <TYPE>GRAPHIC <SEQUENCE>63 <FILENAME>pirs12312019ex1025006.jpg <TEXT> Document 63 - file: pirs12312019ex1025006.jpg
</DOCUMENT> <DOCUMENT> <TYPE>GRAPHIC <SEQUENCE>64 <FILENAME>pirs12312019ex1025007.jpg <TEXT> Document 64 - file: pirs12312019ex1025007.jpg
</DOCUMENT> <DOCUMENT> <TYPE>GRAPHIC <SEQUENCE>65 <FILENAME>pirs12312019ex1025008.jpg <TEXT> Document 65 - file: pirs12312019ex1025008.jpg
</DOCUMENT> <DOCUMENT> <TYPE>GRAPHIC <SEQUENCE>66 <FILENAME>pirs12312019ex1025009.jpg <TEXT> Document 66 - file: pirs12312019ex1025009.jpg
</DOCUMENT> <DOCUMENT> <TYPE>GRAPHIC <SEQUENCE>67 <FILENAME>pirs12312019ex1025010.jpg <TEXT> Document 67 - file: pirs12312019ex1025010.jpg
</DOCUMENT> <DOCUMENT> <TYPE>GRAPHIC <SEQUENCE>68 <FILENAME>pirs12312019ex1025011.jpg <TEXT> Document 68 - file: pirs12312019ex1025011.jpg
</DOCUMENT> <DOCUMENT> <TYPE>GRAPHIC <SEQUENCE>69 <FILENAME>pirs12312019ex1025012.jpg <TEXT> Document 69 - file: pirs12312019ex1025012.jpg
</DOCUMENT> <DOCUMENT> <TYPE>GRAPHIC <SEQUENCE>70 <FILENAME>pirs12312019ex1026001.jpg <TEXT> Document 70 - file: pirs12312019ex1026001.jpg
</DOCUMENT> <DOCUMENT> <TYPE>GRAPHIC <SEQUENCE>71 <FILENAME>pirs12312019ex1026002.jpg <TEXT> Document 71 - file: pirs12312019ex1026002.jpg
</DOCUMENT> <DOCUMENT> <TYPE>GRAPHIC <SEQUENCE>72 <FILENAME>pirs12312019ex1026003.jpg <TEXT> Document 72 - file: pirs12312019ex1026003.jpg
</DOCUMENT> <DOCUMENT> <TYPE>GRAPHIC <SEQUENCE>73 <FILENAME>pirs12312019ex1026004.jpg <TEXT> Document 73 - file: pirs12312019ex1026004.jpg
</DOCUMENT> <DOCUMENT> <TYPE>GRAPHIC <SEQUENCE>74 <FILENAME>pirs12312019ex-43001.jpg <TEXT> Document 74 - file: pirs12312019ex-43001.jpg
</DOCUMENT> <DOCUMENT> <TYPE>GRAPHIC <SEQUENCE>75 <FILENAME>pirs12312019ex-43002.jpg <TEXT> Document 75 - file: pirs12312019ex-43002.jpg
</DOCUMENT> <DOCUMENT> <TYPE>GRAPHIC <SEQUENCE>76 <FILENAME>pirs12312019ex-43003.jpg <TEXT> Document 76 - file: pirs12312019ex-43003.jpg
</DOCUMENT> <DOCUMENT> <TYPE>GRAPHIC <SEQUENCE>77 <FILENAME>pirs12312019exh1031001.jpg <TEXT> Document 77 - file: pirs12312019exh1031001.jpg
</DOCUMENT> <DOCUMENT> <TYPE>GRAPHIC <SEQUENCE>78 <FILENAME>pirs12312019exh1031002.jpg <TEXT> Document 78 - file: pirs12312019exh1031002.jpg
</DOCUMENT> <DOCUMENT> <TYPE>GRAPHIC <SEQUENCE>79 <FILENAME>pirs12312019exh1031003.jpg <TEXT> Document 79 - file: pirs12312019exh1031003.jpg
</DOCUMENT> <DOCUMENT> <TYPE>GRAPHIC <SEQUENCE>80 <FILENAME>pirs12312019exh1031004.jpg <TEXT> Document 80 - file: pirs12312019exh1031004.jpg
</DOCUMENT> <DOCUMENT> <TYPE>GRAPHIC <SEQUENCE>81 <FILENAME>pirs12312019exh1031005.jpg <TEXT> Document 81 - file: pirs12312019exh1031005.jpg
</DOCUMENT> <DOCUMENT> <TYPE>GRAPHIC <SEQUENCE>82 <FILENAME>pirs12312019exh1032001.jpg <TEXT> Document 82 - file: pirs12312019exh1032001.jpg
</DOCUMENT> <DOCUMENT> <TYPE>GRAPHIC <SEQUENCE>83 <FILENAME>pirs12312019exh1032002.jpg <TEXT> Document 83 - file: pirs12312019exh1032002.jpg
</DOCUMENT> <DOCUMENT> <TYPE>GRAPHIC <SEQUENCE>84 <FILENAME>pirs12312019exh1032003.jpg <TEXT> Document 84 - file: pirs12312019exh1032003.jpg
</DOCUMENT> <DOCUMENT> <TYPE>GRAPHIC <SEQUENCE>85 <FILENAME>pirs12312019exh1032004.jpg <TEXT> Document 85 - file: pirs12312019exh1032004.jpg
</DOCUMENT> <DOCUMENT> <TYPE>GRAPHIC <SEQUENCE>86 <FILENAME>pirs12312019exh1032005.jpg <TEXT> Document 86 - file: pirs12312019exh1032005.jpg
</DOCUMENT> <DOCUMENT> <TYPE>GRAPHIC <SEQUENCE>87 <FILENAME>pirs12312019exh1032006.jpg <TEXT> Document 87 - file: pirs12312019exh1032006.jpg
</DOCUMENT> <DOCUMENT> <TYPE>GRAPHIC <SEQUENCE>88 <FILENAME>pirs12312019exh1032007.jpg <TEXT> Document 88 - file: pirs12312019exh1032007.jpg
</DOCUMENT> <DOCUMENT> <TYPE>GRAPHIC <SEQUENCE>89 <FILENAME>programpipeline.jpg <TEXT> Document 89 - file: programpipeline.jpg
</DOCUMENT> <DOCUMENT> <TYPE>GRAPHIC <SEQUENCE>90 <FILENAME>prs060a10.jpg <TEXT> Document 90 - file: prs060a10.jpg
</DOCUMENT> <DOCUMENT> <TYPE>GRAPHIC <SEQUENCE>91 <FILENAME>prs343a03.jpg <TEXT> Document 91 - file: prs343a03.jpg
</DOCUMENT> <DOCUMENT> <TYPE>GRAPHIC <SEQUENCE>92 <FILENAME>prs3432a03.jpg <TEXT> Document 92 - file: prs3432a03.jpg
</DOCUMENT> <DOCUMENT> <TYPE>GRAPHIC <SEQUENCE>93 <FILENAME>prs06010kfigurea01.jpg <TEXT> Document 93 - file: prs06010kfigurea01.jpg
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