Leases (Details) $ in Thousands	1 Months Ended				12 Months Ended
	Jun. 30, 2022 USD ($) ft²	May 31, 2022 USD ($) ft²	Jul. 31, 2021 USD ($) ft²	Apr. 30, 2017 USD ($) ft²	Dec. 31, 2023 USD ($) ft² building item	Dec. 31, 2022 USD ($)
Lessee, Lease, Description [Line Items]
Area of leased space | ft²					162,000
Number of building leased | building					2
Tenant improvement allowance					$ 6,838	$ 8,900
Area of subleased property | ft²			21,000
Option to terminate sublease			false
Monthly base rent			$ 100
Increase in annual base rent (as a percent)			3.00%
Premium component in sublease income			$ 4,200
Percentage of excess sublease income over lease obligations received to be shared with lessor			50.00%
Premium component in sublease income to be shared with lessor			$ 2,100
Percentage of excess sublease income over lease obligations to be retained			50.00%
Expected sublease income			$ 13,100
Decrease in operating lease liabilities					3,001	$ 1,024
Sublease
Lessee, Lease, Description [Line Items]
Tenant improvement allowance					6,490
Expects to receive base rent					$ 51,726
Dublin
Lessee, Lease, Description [Line Items]
Area of leased space | ft²		700		6,100
Annual base rent expenses		$ 200		$ 400
Decrease in operating lease assets		1,400
Decrease in operating lease liabilities		1,500
Loss on sale of furniture and equipment		$ 100
Lease term		2 years
Option to terminate		true
Lease termination notice period		3 months
Operating lease expenses		$ 400
South San Francisco
Lessee, Lease, Description [Line Items]
Area of subleased property | ft²	78,000
South San Francisco | Sublease
Lessee, Lease, Description [Line Items]
Option to terminate sublease	False
Monthly base rent	$ 500
Increase in annual base rent (as a percent)	3.00%
Reduction in expenses	$ 6,500
Tenant improvement allowance	8,900
Expects to receive base rent	51,700
Premium component in sublease income	$ 13,500
Percentage of excess sublease income over lease obligations received to be shared with lessor	50.00%
Premium component in sublease income to be shared with lessor	$ 6,700
Percentage of excess sublease income over lease obligations to be retained	50.00%
Number of buildings in which office and laboratory space leased | item					2