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Revenue - Development and Commercialization Agreement (Details) - USD ($)
1 Months Ended 3 Months Ended 12 Months Ended
Mar. 31, 2020
Jun. 30, 2019
Feb. 28, 2018
Dec. 31, 2021
Sep. 30, 2021
Jun. 30, 2021
Mar. 31, 2021
Dec. 31, 2020
Sep. 30, 2020
Jun. 30, 2020
Mar. 31, 2020
Dec. 31, 2021
Dec. 31, 2020
Dec. 31, 2019
Dec. 31, 2016
Collaborative Arrangements and Co-Promote Agreement                              
Milestone payment       $ 14,946,000 $ 13,194,000 $ 12,914,000 $ 14,257,000 $ 18,730,000 $ 18,257,000 $ 15,008,000 $ 19,862,000 $ 55,311,000 $ 71,857,000 $ 73,414,000  
Percentage of profit share     33.00%                 35.00%      
YUPELRI Monotherapy                              
Collaborative Arrangements and Co-Promote Agreement                              
Milestone payment       $ 15,344,000 $ 13,806,000 $ 14,621,000 $ 12,908,000 $ 13,550,000 $ 12,960,000 $ 10,589,000 $ 12,880,000        
Mylan                              
Collaborative Arrangements and Co-Promote Agreement                              
Percentage of profit share                       65.00%      
Viatris                              
Collaborative Arrangements and Co-Promote Agreement                              
Milestone payment $ 1,500,000                            
Upfront payment receivable   $ 18,500,000                          
Percentage of profit share                       65.00%      
Viatris | Revefenacin Monotherapy (TD-4208)                              
Collaborative Arrangements and Co-Promote Agreement                              
Initial cash payment                             $ 15,000,000.0
Milestone payment                       $ 160,000,000.0      
Transaction price                             $ 15,000,000.0
Viatris | YUPELRI Monotherapy                              
Collaborative Arrangements and Co-Promote Agreement                              
Milestone payment   9,000,000.0                          
Viatris | YUPELRI Monotherapy | Development and Commercialization Agreement                              
Collaborative Arrangements and Co-Promote Agreement                              
Milestone payment                       160,000,000.0      
Viatris | Future potential combination products                              
Collaborative Arrangements and Co-Promote Agreement                              
Milestone payment   7,500,000                   45,000,000.0      
Viatris | Sales milestones                              
Collaborative Arrangements and Co-Promote Agreement                              
Milestone payment   37,500,000                   205,000,000.0      
Viatris | Sales milestones | YUPELRI Monotherapy                              
Collaborative Arrangements and Co-Promote Agreement                              
Milestone payment                       150,000,000.0      
Viatris | Regulatory actions | YUPELRI Monotherapy                              
Collaborative Arrangements and Co-Promote Agreement                              
Milestone payment                       $ 10,000,000.0      
Viatris | Development and Sales Milestones | Future potential combination products                              
Collaborative Arrangements and Co-Promote Agreement                              
Milestone payment   $ 54,000,000.0                          
Pfizer                              
Collaborative Arrangements and Co-Promote Agreement                              
Initial cash payment                           10,000,000.0  
Number of performance obligations                       2      
Pfizer | Sales milestones                              
Collaborative Arrangements and Co-Promote Agreement                              
Milestone payment                           $ 240,000,000.0