8-K

UNITED STATES

SECURITIES AND EXCHANGE COMMISSION

Washington, DC  20549

FORM 8-K

Current Report Pursuant

to Section 13 or 15(d) of the

Securities Exchange Act of 1934

Date of Report (Date of earliest event Reported): January 10, 2022

THERAVANCE BIOPHARMA, INC.

(Exact Name of Registrant as Specified in its Charter)

Cayman Islands	001-36033	Not Applicable
(State or Other Jurisdiction of	(Commission File Number)	(I.R.S. Employer Identification
Incorporation)		Number)

PO Box 309

Ugland House, South Church Street

George Town, Grand Cayman, Cayman Islands KY1-1104

(650) 808-6000

(Addresses, including zip code, and telephone numbers, including area code, of principal executive offices)

Check the appropriate box below if the Form 8-K filing is intended to simultaneously satisfy the filing obligation of the registrant under any of the following provisions (see General Instruction A.2. below):

¨         Written communications pursuant to Rule 425 under the Securities Act (17 CFR 230.425)

¨         Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12)

¨         Pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b))

¨         Pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR 240.13e-4(c))

Securities registered pursuant to Section 12(b) of the Act:

Title of each class	Trading Symbol(s)	Name of each exchange on which registered
Ordinary Share $0.00001 Par Value	TBPH	NASDAQ Global Market

Indicate by check mark whether the registrant is an emerging growth company as defined in Rule 405 of the Securities Act of 1933 (§ 230.405 of this chapter) or Rule 12b-2 of the Securities Exchange Act of 1934 (§ 240.12b-2 of this chapter).

Emerging growth company    ¨

If an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying with any new or revised financial accounting standards provided pursuant to Section 13(a) of the Exchange Act. ¨

Item 7.01. Regulation FD Disclosure.

The information in this Current Report (including Exhibits 99.1 and 99.2) is being furnished and shall not be deemed “filed” for the purposes of Section 18 of the Securities Exchange Act of 1934, as amended, or otherwise subject to the liabilities of that Section. The information in this Current Report (including Exhibits 99.1 and 99.2) shall not be incorporated by reference into any registration statement or other document pursuant to the Securities Act of 1933, as amended, except as shall be expressly set forth by specific reference in such filing.

Members of the Theravance Biopharma, Inc. management team will be presenting at the 40th Annual J.P. Morgan Healthcare Conference on January 13, 2022 and, from January 10-13, 2022, conducting one-on-one meetings with analysts and investors during the conference using a slide presentation which is being furnished pursuant to Regulation FD as Exhibit 99.1 to this Current Report on Form 8-K and is incorporated herein by reference. Additionally, a copy of an Appendix of additional materials is furnished as Exhibit 99.2 to this Current Report and is incorporated herein by reference.

Item 9.01. Financial Statements and Exhibits.

(d) Exhibits.

99.1 Slide deck entitled JP Morgan Healthcare Conference

99.2 Slide deck entitled Appendix Slides to Investor Presentation

104 Cover Page Interactive Data File (cover page XBRL tags embedded within the Inline XBRL document)

SIGNATURE

Pursuant to the requirements of the Securities Exchange Act of 1934, as amended, the registrant has duly caused this report to be signed on its behalf by the undersigned hereunto duly authorized.

	THERAVANCE BIOPHARMA, INC.
Date: January 10, 2022	By: /s/ Andrew Hindman
	Andrew Hindman
	Senior Vice President and Chief Financial Officer

EX-99.1

Exhibit 99.1

JP Morgan Healthcare Conference January 13, 2022 THERAVANCE BIOPHARMA ® , THERAVANCE ® , the Cross/Star logo and MEDICINES THAT MAKE A DIFFERENCE ® are registered trademarks of the Theravance Biopharma group of companies (in the U.S. and certain other countries). All third party trademarks used herein are the property of their respective owners. © 2022 Theravance Biopharma. All rights reserved.

Under the safe harbor provisions of the U . S . Private Securities Litigation Reform Act of 1995 , the company cautions investors that any forward - looking statements or projections made by the company are subject to risks and uncertainties that may cause actual results to differ materially from the forward - looking statements or projections . Examples of forward - looking statements in this presentation may include the Company's goals, designs, strategies, plans and objectives, the impact of the Company’s restructuring plan, ability to provide value to shareholders, the Company's regulatory strategies and timing of clinical studies (including the data therefrom), the potential characteristics, benefits and mechanisms of action of the Company's product and product candidates, the potential that the Company's research programs will progress product candidates into the clinic, the Company's expectations for product candidates through development and the market for products being commercialized, the Company's expectations regarding its allocation of resources, potential regulatory actions and commercialization (including differentiation from other products or potential products and addressable market), product sales or profit share revenue and the Company's expectations for its expenses, excluding share - based compensation and other financial results . The company’s forward - looking statements are based on the estimates and assumptions of management as of the date of this presentation and are subject to risks and uncertainties that may cause the actual results to be materially different than those projected, such as risks related to the impacts on the COVID - 19 global pandemic on our business, disagreements with Innoviva , Inc . and TRC LLC, the uncertainty of arbitration and litigation and the possibility that the results of these proceedings could be adverse to the Company, additional future analysis of the data resulting from our clinical trial(s), delays or difficulties in commencing, enrolling or completing clinical studies, the potential that results from clinical or non - clinical studies indicate the Company's compounds, products or product candidates are unsafe, ineffective or not differentiated, risks of decisions from regulatory authorities that are unfavorable to the Company, the feasibility of undertaking future clinical trials based on policies and feedback from regulatory authorities, dependence on third parties to conduct clinical studies, delays or failure to achieve and maintain regulatory approvals for product candidates, risks of collaborating with or relying on third parties to discover, develop, manufacture and commercialize products, and risks associated with establishing and maintaining sales, marketing and distribution capabilities with appropriate technical expertise and supporting infrastructure, ability to retain key personnel, the impact of the Company’s restructuring actions on its employees, partners and others . Other risks affecting Theravance Biopharma are in the company's Form 10 - Q filed with the SEC on November 8 , 2021 , and other periodic reports filed with the SEC . Forward - looking statements 2

Rapid transition to a streamlined, respiratory focused Theravance Biopharma TBPH holds 85% economic interest in upward - tiering royalty stream of 6.5% – 10% payable by GSK (net of TRC expenses paid and the amount of cash, if any, expected to be used by TRC pursuant to the TRC Agreement over the next four fiscal quarters). 75% of TRC income received is pledged to service outstanding notes, 25% of royalties retained by TBP H. Our non - recourse Triple II 9.5% Fixed Rate Term Notes are due on or before 2035. 1. Source: Bloomberg GSK Analysts Consensus December 16, 2021; 2. Source: TBPH Analysts Consensus [8] December 9, 2021. 3. Regular and c ont ingent workers; 4. Excluding share - based compensation (SBC) and one - time restructuring, severance and termination costs (estimated $18 – 20M between 2021 and 2022, of which the majority will be incurred by Q1 2022). CO PD, chronic obstructive pulmonary disease; JAK, Janus kinase; PIFR, peak inspiratory flow rate. 3 Overarching goal: maximize shareholder value ‣ Track record of innovation leading to several approved COPD and asthma medicines, including: – TRELEGY: a respiratory medicine developed by Glaxo Group Limited in collaboration with the Company’s predecessor, Theravance, In c. – YUPELRI ® : discovered and developed by Theravance Biopharma, launched in 2019, and is now commercialized in partnership with Viatris Inc. ‣ Strong, growing cash flows from TRELEGY and YUPELRI provide significant value to shareholders ‣ TRELEGY and YUPELRI have significant potential for future growth – TRELEGY: high growth, long patent life respiratory medicine expected to generate global peak - year sales of $3.2 billion 1 – YUPELRI: remains early in its lifecycle, has demonstrated quarter - over - quarter market share growth, with potential US peak - year sales ~ $400 million 2 ‣ Headcount reduced by ~75% (~270 positions 3 ); majority of reduction completed November 2021, remainder February 2022 ‣ Total annualized operating expense 4 savings of ~$170 million in 2022 ‣ PIFR clinical study, in partnership with Viatris , intended to capture more of the addressable market and further strengthen its competitive advantage ‣ Investigational inhaled JAK inhibitor portfolio; includes nezulcitinib (TD - 0903), initially targeting acute lung injury and fibrotic disease 6LJQLILFDQW FRVW UHGXFWLRQ SURJUDP UHGXFHV &RPSDQ\ VL]H WR EHFRPH VXVWDLQDEO\ FDVK IORZ SRVLWLYH EHJLQQLQJ + Focus on leveraging expertise in developing and commercializing respiratory therapeutics Streamlined R&D investment to focus on highest value core respiratory opportunities Leverage partnerships to unlock value of pipeline assets

Key pillars of respiratory - focused value creation plan 1. Source: TBPH Analysts Consensus [8] December 9, 2021. 2. Source: Bloomberg GSK Analysts Consensus December 16, 2021. JAK, Jan us kinase; PIFR, peak inspiratory flow rate. 3. TBPH holds 85% economic interest in upward - tiering royalty stream of 6.5% – 10% payable by GSK (net of TRC expenses paid and the amount of cash, if any, expected to be used by TRC pursuant to the TRC Agreement over the next four fiscal quarters). 75% of TRC income received is pledged to service outstanding notes, 25% of royalties retained by TBPH. Our non - recour se Triple II 9.5% Fixed Rate Term Notes are due on or before 2035. 4 <83(/5, Š ‣ Consensus US peak year sales of ~$ 400 million 1 ‣ Q3 2021 net sales of $ 39 million implies run rate annual sales of ~$160 million ‣ YUPELRI remains early in its product lifecycle ; has demonstrated quarter - over - quarter market share growth ‣ TBPH hospital - based and Viatris community - based sales forces continue driving growth ‣ PIFR study intended to capture more of the addressable market and further strengthen its competitive advantage ‣ Long patent life Core Respiratory Pipeline Near - term catalysts will inform upside potential of focused pipeline: ‣ Inhaled JAK inhibitor portfolio, with the most advanced candidate being nezulcitinib (TD - 0903), initially targeting acute lung injury and fibrotic disease ‣ Dry - powder inhaled JAK inhibitors to proceed into clinic with next generation compounds after securing partnership TRELEGY ‣ Consensus global peak year sales of ~ $3.2 billion 2 ‣ Q3 2021 net sales of $ 449 million implies run rate annual sales of ~$1.8 billion 3 ‣ Long patent life ‣ TRELEGY - related cash flows to TBPH to increase substantially (once non - recourse note is fully repaid) 3

FDA - approved for maintenance treatment of COPD First and only once - daily, LAMA (long - acting muscarinic agent) nebulized maintenance medicine for COPD

‣ Once - daily LAMAs are first - line therapy for moderate - to - very severe COPD 1 ‣ 9% of COPD patients (~800,000) use nebulizers for ongoing maintenance therapy; 41% use nebulizers at least occasionally for bronchodilator therapy 2 <83(/5, Š UHYHIHQDFLQ LQKDODWLRQ VROXWLRQ 1. Global Strategy for Diagnosis, Management, and Prevention of COPD, 2018. 2. TBPH market research (N = 160 physicians); refers to US COPD patients. COPD, chronic obstructive pulmonary disease; LAMA, long - acting muscarinic antagonist. 6 ‣ TBPH and VTRS worldwide strategic collaboration to develop and commercialize nebulized YUPELRI (revefenacin) ‣ Companies co - promote under US profit/loss share 65% 35% FDA - approved for maintenance treatment of COPD First and only once - daily, nebulized maintenance medicine for COPD

Where the market has been 6RXUFH 6+$ 0(7<6 WKURXJK 4 ¶ /$ 1(% ORQJ DFWLQJ QHEXOL]HU 7 ‣ Universal brand challenges – Reduced office visits – Reduced/limited new treatment starts ‣ Pulmonologists enlisted for ER, ICU, hospital, COVID outpatient evaluation ‣ Overall new product starts for pulmonologists still down compared with 2019; lag behind other specialties 1 ‣ Hospital purchasing for the entire LA - NEB market declined markedly in Q1 2020; today still below 2019 levels ‣ Despite down market, YUPELRI shows steady market share and volume growth COVID - 19 placed unprecedented demands on pulmonologists COVID - 19 outbreak coincided with critical period of YUPELRI ® launch Despite impact, YUPELRI sales still increasing

YUPELRI ® hospital sales and community TRx trends Continued market share growth across both the hospital and retail channels 0.3 1.1 2.2 3.4 5.4 6.5 6.3 7.4 7.8 8.7 9.5 0% 5% 10% 15% 20% 25% Hospital LA - NEB Market Share 1 Hospital Market Share YUPELRI LA-NEB Market Share 1. Hospital LA - NEB Market Share - IQVIA DDD through 09/30/2021. 2. Community LA - NEB Market Share - IQVIA XPO Excl. LTC (Retail) and SolutionsRx (DME / Med B FFS) through 7/31/2021 (Q3’21 Community LA - NEB Market Share Incomplete). 3. Retail TRx Volume - Symphony Health METYS Prescription Dashboard through 09/30/2021; 4. Joint VTRS/TBPH Market Research. LA - NEB Market: YUPELRI, BROVANA, LONHALA, PERFOROMIST, arformoterol , formoterol. LA - NEB, long - acting nebulizer. 8 TRx volume represents retail only which is typically 33% of Retail + DME 1.5 6.1 9.8 13.1 15.2 16.3 17.4 18.7 19.7 21.5 22.4 0K 5K 10K 15K 20K 25K 0% 5% 10% 15% 20% 25% Retail TRx Volume 3 Community LA - NEB Market Share 2 Community Market Share with TRx Retail TRx YUPELRI LA-NEB Market Share Most patients who receive YUPELRI in the hospital are discharged with an Rx 4 Q2 4 Q4 Q1 Q2 Q3 Q4 Q1 Q2 Q3 2019 2020 2021 Q2 Q3 Q4 Q1 Q2 Q3 Q4 Q1 Q2 Q3 2019 2020 2021

0 2,000 4,000 6,000 8,000 10,000 YULPELRI Weekly Hospital Doses YUPELRI ® hospital volume has returned to growth Source: IQVIA DDD through 12/24/2021. 9 2019 Growth from launch 2020 Flat 2021 Return to growth Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec

Substantial opportunity for further YUPELRI ® growth ‣ COPD is under - diagnosed 1 ‣ COPD patients with or without symptoms may be treated with rescue and/or maintenance therapies ‣ Estimated patient counts from volume using average ‘days of therapy’ assumptions vary considerably across DME and retail channels 1. American Lung Association. 2. Clarivate COPD Disease Landscape & Forecast US 2021. 3. Revefenacin COPD Joint Venture Research 2016. 10 YUPELRI may be appropriate for COPD patients, including but not limited to: ► Moderate - to - very - severe COPD (73 – 92% 4 ); once - daily LAMAs are first - line therapy for moderate - to - very severe COPD patients ► Patients with suboptimal PIFR (19 – 78% of COPD patients 5 ) ► Patients with cognitive or dexterity challenges ~36% of COPD patients present episodes of cognitive impairment; ~33% of elderly patients have inadequate hand strength for inhalers 6 ► Patients transitioning from hospital to home care after being stabilized on nebulized treatment during hospitalization Growth opportunities within numerous patient segments 4. Safka KA, et al. Chronic Obstr Pulm Dis 2017. 5. Mahler DA, et al. Chronic Obstr Pulm Dis 2019. 6. Armitage JM, Williams SJ Inhaler technique in the elderly. Age Ageing 1988 17:275 - 278. Market share of COPD maintenance therapy just scratching the surface Estimated 2021 YUPELRI Patient Funnel (US) COPD, chronic obstructive pulmonary disease; DME, durable medical equipment; LAMA, long - acting muscarinic antagonist; PIFR, peak inspiratory flow rate.

Favorable YUPELRI ® outlook in 2022 and beyond 11 1. Data on file from TBPH survey of HCPs October 2020 - October 2021. COPD, chronic obstructive pulmonary disease; PIFR, peak inspiratory flow rate; PPE, personal protective equipment ; QD, once a d ay. Additional potential growth opportunities Observations from the field 1 ‣ Pulmonologists / other HCPs have resumed routine testing to evaluate and diagnose COPD patients ‣ In office nebulization for COPD patients has resumed ‣ 99% of hospital - based HCPs support nebulization regardless of COVID - 19 status if proper PPE is worn ‣ More hospitals becoming or are “all neb” ‣ QD dosing important to alleviate health systems overwhelmed by rising COVID - 19 cases (over - taxed hospitals and long - term care facilities) ‣ PIFR 2 study: intended to capture more of the addressable market and further strengthen its competitive advantage ‣ China opportunity : China approval projected for 2024 ; ~$100M PYS opportunity — potential development and sales milestones totaling $54M / low double - digit tiered royalties on net sales

Pipeline focused on highest value core respiratory opportunities 1. Excluding programs that are in the process of being wound down following restructuring. JAK, Janus kinase; PIFR, peak inspiratory flow rate. 12 New Theravance: Core Respiratory Focused pipeline of core respiratory programs 1 Implement partnering strategy to maximize value of pipeline assets ‣ PIFR - 2 Phase IV study intended to capture more of the addressable market and further strengthen its competitive advantage ‣ Inhaled JAK inhibitor portfolio which includes nezulcitinib

A new, respiratory focused Theravance Biopharma 1. TBPH estimate derived from integrating multiple data sources 2. TBPH holds 85% economic interest in upward - tiering royalty st ream of 6.5% – 10% payable by GSK (net of TRC expenses paid and the amount of cash, if any, expected to be used by TRC pursuant to the TRC Agreement over the next four fiscal quarters). 75% of TRC income received is p led ged to service outstanding notes, 25% of royalties received retained by TBPH. All statements concerning TRELEGY ELLIPTA based on publicly available information. ALK5i, transforming growth factor β receptor I kinase inhibitor; CD, Crohn’s di sease; COPD, chronic obstructive pulmonary disease; FF/UMEC/VI, fluticasone furoate/umeclidinium/ vilanterol; JAKi , JAK inhibitor; LAMA, long - acting muscarinic antagonist ; nOH , neurogenic orthostatic hypotension; NRI, norepinephrine reuptake inhibitor; PIFR, peak inspiratory flow rate; UC, ulcerative colitis. 13 Program Indication US Patients 1 Research Phase 1 Phase 2 Phase 3 Filed Marketed Phase 4 Collaborator Respiratory Assets YUPELRI (revefenacin) LAMA COPD patients with suboptimal PIFR >8mm Nezulcitinib (TD - 0903) Inhaled JAKi Acute and chronic lung inflammation, fibrotic disease >32mm Inhaled JAKi Asthma ~25mm Economic Interests TRELEGY 2 FF/UMEC/VI COPD >8mm GSK & Innoviva, Inc. Asthma ~25mm Skin - selective JAKi Dermatological diseases >8mm Non - Core Assets * Ampreloxetine (TD - 9855) NRI S ymptomatic nOH ~350k Izencitinib (TD - 1473) GI JAKi UC ~900k CD ~800k TD - 5202 Irreversible JAK3i Celiac disease UC CD ~5mm Inhaled ALK5i Idiopathic pulmonary fibrosis ~140k Phase 3 Phase 2 Phase 2 Phase 1 Phase 1 Marketed Phase 4 PIFR - 2 Study Marketed Phase 1 Phase 2b/3 Research Marketed *Limited additional capital investment planned post Q1 2022

YUPELRI ® : Phase 4 randomized, double - blind, parallel - group study (PIFR - 2) A Phase 4, Randomized, Double - Blind, Parallel˗Group Study in Adults With Severe to Very Severe COPD and Suboptimal Inspiratory Flow Rate. *Dry powder inhaler (Spiriva ® HandiHaler ®) . FEV 1 , forced expiratory volume in 1 second; PIFR, peak inspiratory flow rate. 14 Primary: Change from baseline in trough FEV 1 on Day 85 Key secondary: Trough overall treatment effect on FEV 1 Study Endpoints Randomization 1:1 Q1’23 Results YUPELRI SPIRIVA ® via HH* Once - daily treatment: 12 weeks N=366 Run - in

Lung - selective JAK inhibitor nezulcitinib demonstrates potential to protect lungs in an IFN γ - driven viral ARDS hyperinflammatory environment *Comparable blockade in lung IL - 13 – pSTAT6 in vivo model; ****p<0.0001. ARDS, acute respiratory distress syndrome; IFN γ , interferon - gamma; IL - 6, interleukin - 6; IP - 10, IFN γ - induced protein 10; JAK, Janus kinase; MCP - 1, monocyte chemoattractant protein - 1; MFI, mean fluorescent intensity; pSTAT1, phosphorylated signal transducer and activator of transcription; TNF α , tumor necrosis factor alpha. 15 0 100000 200000 300000 400000 500000 **** Potential mechanistic rationale for several acute and chronic lung diseases 0 20 40 60 80 100 % I n h i b i t i o n IFNγ, TNFα, + polyI:C treated primary human bronchial epithelium Membrane Permeability Cell Death IP - 10 MCP - 1 IL - 6 Nezulcitinib Placebo IFN γ - induced pSTAT1 in mouse lung in vivo* Vehicle / Vehicle Vehicle / IFN γ Nezulcitinib / IFN γ 1 mg/mL Lung pSTAT1 (MFI)

Study 0188 (NCT: 04402866). Ventilator - free survival is defined as elapsed time (in days) from randomization to first day a participant progresses to IMV or death. CI, confidence interval; CRP, C - Reactive protein; HR, hazard ratio; IMV, invasive mechanical ventilation; ITT, intent - to - treat. 16 Phase 2 study: hospitalized patients with severe COVID - 19 Nezulcitinib n=106 Placebo n=104 Deaths, n (%) 6 (5.7) 13 (12.5) HR (95% CI) 1 0.42 (0.16, 1.12) p - value 2 0.08 Nezulcitinib n=86 Placebo n=85 IMV or Deaths, n (%) 2 (2.3) 11 (12.9) Ventilator - free, n (%) 84 (97.7) 74 (87.1) HR (95% CI) 1 6.15 (1.36, 27.74) p - value 3 0.007 Time from Randomization (days) 0 7 14 21 28 Ventilator - Free Survival CRP <150 mg/L Nezulcitinib n=86 Placebo n=85 Deaths, n (%) 1 (1.2) 9 (10.6) HR (95% CI) 1 0.10 (0.01, 0.77) p - value 2 0.009 0.8 0.7 0.9 1.0 Mortality CRP <150 mg/L 0 7 14 21 28 0.1 0.0 0.2 0.3 Time from Randomization (days) Proportion Time from Randomization (days) 0 7 14 21 28 0.1 0.0 0.2 0.3 Mortality ITT Population Placebo Nezulcitinib

Outcomes of the UK COVID Therapeutics Advisory Panel https://www.gov.uk/government/groups/the - covid - 19 - therapeutics - taskforce https://www.ukri.org/about - us/policies - standards - and - data/data - collection/uk - covid - 19 - therapeutics - advisory - panel/recommended - tr eatments - for - clinical - trials/ 17 355 candidate drug submissions received via open submission system 7 33 recommended drugs to national publicly funded platform trials Nezulcitinib (TD - 0903) Trial recommended to: REMAP - CAP Date: 10 October 2021 Why it was recommended In people with severe COVID - 19, parts of the immune system are very active, which causes inflammation and organ damage, particularly in the lungs. TD - 0903 has a unique inhaled formulation which allows it to block inflammation and tissue damage directly in the lung. This might reduce severe COVID illness and the risk for patients to require to be put in ICU under ventilation.

Economic interest GSK’s TRELEGY ELLIPTA (FF/UMEC/VI): First and only once - daily single inhaler triple therapy

Economic interest in GSK’s TRELEGY 1. TBPH holds 85% economic interest in upward - tiering royalty stream of 6.5% – 10% payable by GSK (net of TRC expenses paid and the amount of cash, if any, expected to be used by TRC pursuant to the TRC Agreement over the next four fiscal quarters). 75% of TRC income received is pledged to service outstanding notes, 25% of royalties retained by TBPH. Our non - recourse Triple II 9.5% Fixed Rate Term Notes are due on or before 2035. All statements concerning TRELEGY based on publicly available information. TRELEGY is FF/UMEC/VI or flutic aso ne furoate/umeclidinium/vilanterol; comprised of inhaled corticosteroid, long - acting muscarinic receptor antagonist, and long - acting β2 agonists, active components of Anoro (UMEC/VI). COPD, chronic obstructive pulmonary disease. 19 TRELEGY Upward - tiering royalties of ~5.5 – 8.5% of global net sales 1 Q3 global net sales of $449M Year - over - year sales growth of 77% from the same period in 2020 TRELEGY now has 53% of US triple therapy patients for COPD and 73% global share 0 100 200 300 400 500 600 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 Monthly TRx Volume (Thousands) Month Post Launch Strongest US ELLIPTA Launch ANORO ELLIPTA ARNUITY ELLIPTA BREO ELLIPTA INCRUSE ELLIPTA Launched in US in November 2017 Source: GSK, Symphony Health Metys monthly TRx data for the time period Sept'13 to Nov'21. TRELEGY Mortality Ad Comm TRELEGY Asthma Approval BREO Asthma Approval TRELEGY

Financial Guidance 1. Excluding share - based compensation (SBC) and one - time restructuring, severance and termination costs (estimated $18 – 20M betwe en 2021 and 2022, of which the majority will be incurred by Q1 2022). 20 Execution of cost - cutting initiatives results in lowered 2021 OPEX guidance 1 : – R&D: updated range of $170 – $180M – SG&A: updated range of $65 – $75M As a result of continued refinement of cost - cutting initiatives, we are also reducing 2022 total OPEX guidance 1 : – R&D: updated range of $45 – 55M – SG&A: updated range of $35 – 45M 2022 guidance includes ~$10M in non - recurring spend, mostly in R&D: – Majority in Q1 to support completion of late - stage programs – OPEX Q2 and onward will reflect recurring spend only Theravance Biopharma is projected to be sustainably cash - flow positive beginning in 2H 2022

Rapid transition to a streamlined, respiratory focused Theravance Biopharma 21 Significant cost reduction program reduces Company size to become sustainably cash - flow positive beginning 2H 2022 Focus on leveraging expertise in developing and commercializing respiratory therapeutics Streamlined R&D investment to focus on highest value core respiratory opportunities Leverage partnerships to unlock value of pipeline non - core assets Overarching goal: maximize shareholder value

Q&A Session Rick E Winningham Chairman and Chief Executive Officer Andrew A. Hindman Senior Vice President, Chief Financial Officer Rhonda F. Farnum Senior Vice President, Commercial and Medical Affairs Richard A. Graham Senior Vice President, Research and Development

YUPELRI ® ( revefenacin ) inhalation solution YUPELRI ® inhalation solution is indicated for the maintenance treatment of patients with chronic obstructive pulmonary disease (COPD) . Important Safety Information (US) YUPELRI is contraindicated in patients with hypersensitivity to revefenacin or any component of this product . YUPELRI should not be initiated in patients during acutely deteriorating or potentially life - threatening episodes of COPD, or for the relief of acute symptoms, i . e . , as rescue therapy for the treatment of acute episodes of bronchospasm . Acute symptoms should be treated with an inhaled short - acting beta 2 - agonist . As with other inhaled medicines, YUPELRI can produce paradoxical bronchospasm that may be life - threatening . If paradoxical bronchospasm occurs following dosing with YUPELRI, it should be treated immediately with an inhaled, short - acting bronchodilator . YUPELRI should be discontinued immediately and alternative therapy should be instituted . YUPELRI should be used with caution in patients with narrow - angle glaucoma . Patients should be instructed to immediately consult their healthcare provider if they develop any signs and symptoms of acute narrow - angle glaucoma, including eye pain or discomfort, blurred vision, visual halos or colored images in association with red eyes from conjunctival congestion and corneal edema . Worsening of urinary retention may occur . Use with caution in patients with prostatic hyperplasia or bladder - neck obstruction and instruct patients to contact a healthcare provider immediately if symptoms occur . Immediate hypersensitivity reactions may occur after administration of YUPELRI . If a reaction occurs, YUPELRI should be stopped at once and alternative treatments considered . The most common adverse reactions occurring in clinical trials at an incidence greater than or equal to 2 % in the YUPELRI group, and higher than placebo, included cough, nasopharyngitis, upper respiratory infection, headache and back pain . Coadministration of anticholinergic medicines or OATP 1 B 1 and OATP 1 B 3 inhibitors with YUPELRI is not recommended . YUPELRI is not recommended in patients with any degree of hepatic impairment . OATP, organic anion transporting polypeptide. 23

About YUPELRI ® ( revefenacin ) inhalation solution YUPELRI ® ( revefenacin ) inhalation solution is a once - daily nebulized LAMA approved for the maintenance treatment of COPD in the US . Market research by Theravance Biopharma indicates approximately 9 % of the treated COPD patients in the US use nebulizers for ongoing maintenance therapy . 1 LAMAs are a cornerstone of maintenance therapy for COPD and YUPELRI ® is positioned as the first once - daily single - agent bronchodilator product for COPD patients who require, or prefer, nebulized therapy . YUPELRI ® ’s stability in both metered dose inhaler and dry powder device formulations suggest that this LAMA could also serve as a foundation for novel handheld combination products . 1. TBPH market research (N=160 physicians); refers to US COPD patients. COPD, chronic obstructive pulmonary disease; LAMA, long - acting muscarinic antagonist. 24

EX-99.2

Exhibit 99.2

THERAVANCE BIOPHARMA ® , THERAVANCE ® , the Cross/Star logo and MEDICINES THAT MAKE A DIFFERENCE ® are registered trademarks of the Theravance Biopharma group of companies (in the U.S. and certain other countries). All third party trademarks used herein are the property of their respective owners. © 2022 Theravance Biopharma. All rights reserved. Appendix Slides to Investor Presentation January 2022

Under the safe harbor provisions of the U . S . Private Securities Litigation Reform Act of 1995 , the company cautions investors that any forward - looking statements or projections made by the company are subject to risks and uncertainties that may cause actual results to differ materially from the forward - looking statements or projections . Examples of forward - looking statements in this presentation may include the Company's goals, designs, strategies, plans and objectives, the impact of the Company’s restructuring plan, ability to provide value to shareholders, the Company's regulatory strategies and timing of clinical studies (including the data therefrom), the potential characteristics, benefits and mechanisms of action of the Company's product and product candidates, the potential that the Company's research programs will progress product candidates into the clinic, the Company's expectations for product candidates through development and the market for products being commercialized, the Company's expectations regarding its allocation of resources, potential regulatory actions and commercialization (including differentiation from other products or potential products and addressable market), product sales or profit share revenue and the Company's expectations for its expenses, excluding share - based compensation and other financial results . The company’s forward - looking statements are based on the estimates and assumptions of management as of the date of this presentation and are subject to risks and uncertainties that may cause the actual results to be materially different than those projected, such as risks related to the impacts on the COVID - 19 global pandemic on our business, disagreements with Innoviva , Inc . and TRC LLC, the uncertainty of arbitration and litigation and the possibility that the results of these proceedings could be adverse to the Company, additional future analysis of the data resulting from our clinical trial(s), delays or difficulties in commencing, enrolling or completing clinical studies, the potential that results from clinical or non - clinical studies indicate the Company's compounds, products or product candidates are unsafe, ineffective or not differentiated, risks of decisions from regulatory authorities that are unfavorable to the Company, the feasibility of undertaking future clinical trials based on policies and feedback from regulatory authorities, dependence on third parties to conduct clinical studies, delays or failure to achieve and maintain regulatory approvals for product candidates, risks of collaborating with or relying on third parties to discover, develop, manufacture and commercialize products, and risks associated with establishing and maintaining sales, marketing and distribution capabilities with appropriate technical expertise and supporting infrastructure, ability to retain key personnel, the impact of the Company’s restructuring actions on its employees, partners and others . Other risks affecting Theravance Biopharma are in the company's Form 10 - Q filed with the SEC on November 8 , 2021 , and other periodic reports filed with the SEC . Forward - looking statements 2

COPD and Asthma Background

COPD is characterized by persistent airflow limitation that is not fully reversible ‣ Progressive, partially irreversible airway damage – Chronic bronchitis: Chronic inflammation of bronchi with mucus hypersecretion, leading to airway narrowing and obstruction of airflow – Emphysema: Destruction of alveolar walls, leading to fewer, larger alveoli and loss of lung elastic recoil, causing chronic lung hyperinflation and compromising expiratory flow ‣ Clinically defined as post - bronchodilator FEV 1 :FVC ratio <70% in a spirometry test ‣ Symptoms, which can become acute and lead to exacerbation, include chronic cough, shortness of breath, and chronic sputum production – Symptoms typically progress slowly – Environmental stimuli including pollutants and bacterial / viral infections can cause acute worsening ‣ Most common risk factor is tobacco smoking; others include occupational exposure to dusts and chemicals Source: DRG. COPD, chronic obstructive pulmonary disease; FEV 1 , forced expiratory volume in 1 second; FVC, forced vital capacity. 4

Three classes of inhaled medicines form backbone of long - term maintenance therapy for both COPD and asthma Class Mechanism of Action Key Brands* (Mfg., 2020 Global Net Sales) LABA Long - acting beta agonists Activate beta 2 - adrenergic receptors to reduce free intracellular calcium, thereby relaxing smooth muscle, reducing mucus secretion, and increasing mucociliary function. Brovana (Sunovion, $273 M) Perforomist (VTRS, $213 M) Serevent (GSK, $62 M) LAMA Long - acting muscarinic antagonists Also known as anticholinergics. Bind to muscarinic receptors and inhibit bronchoconstriction and mucus secretion stimulated by the interaction of acetylcholine with these receptors. Spiriva (BI, $2.0 B) Incruse (GSK, $283 M) YUPELRI (VTRS/TBPH, $143 M) ICS In haled corticosteroids Bind to glucocorticoid receptors, reducing transcription of genes involved in inflammatory response, reducing number of immune cells in mucosa, inhibiting T - cell activation, promoting eosinophil apoptosis, inhibiting nitric oxide synthase, reducing mucus secretion, and increasing beta 2 - adrenergic receptor production. Pulmicort (AZ, $1.0 B) Flovent (GSK, $535 M) Asmanex (Merck, $231 M) Source: IQVIA Analytics Link (MNFG Reported Sales when publicly disclosed, MIDAS Value when not) Note: short - acting beta agonists and muscarinic antagonists are widely used for rescue therapy and occasionally on a regular bas is for maintenance. Also, a variety of biologics are increasingly used as add - on therapy in severe asthma. * See specific prescribing information for each product for specific use in COPD and/or asthma. Some agents are not approved fo r C OPD (e.g. Asmanex by MERCK). COPD, chronic obstructive pulmonary disease. 5 Types of Delivery Devices MDI (metered dose inhaler) DPI (dry powder inhaler) SMI (soft mist inhaler) Nebulizer

'XDO FRPELQDWLRQV DQG PRUH UHFHQWO\ WULSOH FRPELQDWLRQV KDYH EHFRPH PDUNHW OHDGHUV Dual Combinations Key Brands (Mfg., 2020 Global Net Sales) ICS / LABA Indicated for both COPD & asthma Symbicort (AZ, $2.7 B) Advair (GSK, $2.0 B) Breo (GSK, $1.4 B) Generics ($930 M) LABA / LAMA Indicated only for COPD Stiolto (BI, $730 M) Anoro (GSK, $713 M) Ultibro (Novartis, $623 M) Bevespi (AZ, $48 M) Source: IQVIA Analytics Link. BID, twice a day; COPD, chronic obstructive pulmonary disease; DPI, dry powder inhaler; HFA - pMDI , hydrofluoroalkane pressurized metered dose inhaler; ICS, inhaled corticosteroids; LABA, long - acting beta 2 agonists; LAMA, long - acting muscarinic antagonist; QD, once a day. 6 Triple Combos Dosing & Components COPD Status Asthma Status Trelegy GSK $1.1 B QD Multi - dose DPI Vilanterol, umeclidinium & fluticasone furoate Approved • US, Sep - 17 • EU, Jul - 17 • Japan, Nov - 20 • China, Nov - 19 Approved • US, Sep - 20 • Japan, Nov - 20 Rejected in EU with no plans to pursue further Trimbow Chiesi $281 M BID HFA - pMDI Formoterol, glycopyrrolate & beclometasone Approved • EU, Jul - 17 US Phase 3 trial listed in Mar - 20 but has not yet started Approved • EU, Feb - 21 Breztri AstraZeneca $28 M BID HFA - pMDI Formoterol, glycopyrronium & budesonide Approved • US, Jul - 20 • EU, Dec - 20 • Japan, Jun - 19 • China, Dec - 19 Phase 3 on - going with expected completion in Q3 2023 Enerzair Novartis $3 M QD Single - dose DPI Indacaterol, glycopyrronium & mometasone Not in development for COPD Approved • EU, Jul - 20 • Japan, Jun - 20 Not in development for US (would not be QD)

2YHUYLHZ RI QHEXOL]HG SURGXFWV IRU PDLQWHQDQFH WKHUDS\ Nebulizers provide a user - friendly option for providers and their COPD patients : ‣ Require only normal tidal breathing and do not require extra effort generating adequate inspiratory flow rate ‣ No hand - breath coordination is needed ‣ Many patients are 100% covered as durable medical equipment (DME) through Medicare Part B COPD, chronic obstructive pulmonary disease; DME, durable medical equipment; LABA, long - acting beta 2 agonists; LAMA, long - acting muscarinic antagonist; SABA, short - acting beta - agonists; SAMA, short - acting muscarinic - antagonist. 7 Nebulized Products Used for Maintenance Therapy Class Dosing & Components Launch / Gx Status YUPELRI Viatris (formerly Mylan) LAMA QD (1x per day) Revefenacin • US, Nov - 18 Lonhala Sunovion LAMA BID (2x per day) Glycopyrrolate • US, Feb - 18 Brovana Sunovion LABA BID (2x per day) Arformoterol Tartrate • US, Mar - 07 • Gx, Jun - 21 Perforomist Viatris (formerly Mylan) LABA BID (2x per day) Formoterol Fumarate • US, Aug - 07 • Gx, Jun - 21 DuoNeb Viatris (formerly Mylan) SABA/ SAMA QID (4x per day, up to 6x) Ipratropium Albuterol • US, Jun - 01 • Gx, Jul - 07 /RQJ $FWLQJ 1HE 0DUNHW ,QGLFDWHG IRU /RQJ $FWLQJ 1HEXOL]HG 0DLQWHQDQFH 7KHUDS\ Short - Acting (rescue) which is used for regular daily (maintenance) therapy

FDA - approved for the maintenance treatment of COPD First and only once - daily, LAMA (long - acting muscarinic agent) nebulized maintenance medicine for COPD

YUPELRI ® ( revefenacin ) is the first and only once - daily, nebulized maintenance medicine for COPD COPD, chronic obstructive pulmonary disease; LABA, long - acting beta 2 agonists; LAMA, long - acting muscarinic antagonist; PIFR, peak inspiratory flow rate. 9 Companies co - promote under US profit/loss share 35% TBPH VTRS ‣ ~45% of COPD patients in the US have a nebulizer at home ‣ Nebulized therapy associated with reduced hospital readmissions in low PIFR patients ‣ Patients with cognitive or dexterity challenges may be candidates for nebulized therapy Enduring Patient Niche ‣ Viatris partnership brings commercial strength in nebulized segment ‣ YUPELRI complementary to existing nebulized LABA treatments ‣ Planned clinical study aimed at helping to better inform decisions when physicians are designing a personalized COPD treatment plan with their patients. – Success in this study would capture more of YUPELRI's addressable market and further strengthen its competitive advantage Growing Market Opportunity ࿢ 2QFH GDLO\ /$0$V DUH ILUVW OLQH WKHUDS\ IRU PRGHUDWH WR VHYHUH &23' SDWLHQWV ࿢ <83(/5, LV WKH RQO\ RQFH GDLO\ QHEXOL]HG /$0$ DYDLODEOH Unmet Need for Nebulized LAMA therapy

9.1 16.5 29.6 36.8 30.3 37.0 38.7 36.9 41.8 39.4 COVID - 19 placed unprecedented demands on pulmonologists COVID - 19 outbreak coincided with critical period of YUPELRI ® launch Where the market has been 1. Source: SHA METYS through Q3’21 ; 2. Source: IQVIA DDD through Sep’21. 2. COPD, chronic obstructive pulmonary disease; LA - NEB, long - acting nebulizer. 10 ‣ Universal brand challenges – Reduced office visits – Reduced/limited new treatment starts ‣ Pulmonologists enlisted for ER, ICU, hospital, COVID outpatient evaluation ‣ Hospital purchasing for the entire LA - NEB market declined markedly in Q1 2020 and remains below 2019 levels ‣ Despite down market, YUPELRI shows steady market share and volume growth Total Net Sales ($M) Despite impact, YUPELRI ® sales still increasing 2 Q2 Q3 Q4 Q1 Q2 Q3 Q4 Q1 Q2 Q3 2019 2020 2021 0.0 0.3 1.1 2.2 3.4 5.4 6.5 6.3 7.4 7.8 8.7 9.5 0 5,000 10,000 15,000 20,000 25,000 30,000 35,000 Days of Therapy Total LA Neb Market Hospital Purchasing Trends: COPD Long - Acting Nebulized Market YUPELRI LA Neb Share (%) Q4 4 Q2 Q3 Q4 Q1 Q2 Q3 Q4 Q1 Q2 Q3 2018 2019 2020 2021 Nebulized Product Growth YoY TRx Growth 1 12 Months Ending Jul ’21 vs Same Time Last Year - 10% - 31% - 14% - 11% - 3% 31% Neb Sub Total LONHALA MAGNAIR BROVAVA ALBUTEROL/IPRATROPIUM PERFOROMIST YUPELRI 2 2 ‣ Overall new product starts for pulmonologists still down vs 2019; lag behind other specialties 1 - 17% New - to - product Rx growth - 8% TRx growth

YUPELRI ® more likely to be added to Neb LABA than be a conversion from long - acting Neb competitors ‣ Budesonide (ICS), Perforomist and Brovana are the products most often used in combination with YUPELRI – 40 – 50% of YUPELRI patients are also on Neb LABA – 35 – 40% of YUPELRI patients are on open triple therapy (LAMA/LABA/ICS) with the majority being all nebulized ‣ Conversions mostly come from SA Nebs and LA Handhelds with fewer conversions from Neb LABAs ‣ Generic availability of Neb LABAs allows for cheaper patient OOP costs with combo use ‣ Drivers to nebulized therapy continue to be: – Cognitive/dexterity challenges – Patient preference based on prior experience – Access and low out of pocket costs for Medicare Part B patients – Transition from hospital to home care – Suboptimal PIFR Source: IQVIA LAAD Patient - Level Claims Data through Jun’21. ICS, inhaled corticosteroid; LABA, long - acting beta 2 agonists; LAMA, long - acting muscarinic antagonist; OOP, out of pocket; PIFR, peak inspiratory flow rate. 11 YUPELRI Source of Business

‣ Shipments from wholesalers to outlets; Does not include filled Rxs ‣ Outlet sub - categories allow for distinction between inpatient and outpatient entities ‣ Additional hospital volume in VA and outlets that do not report to DDD ‣ Majority of YUPELRI business flows through the DME channel ‣ Data available via SolutionsRx Management Group – Captures the DME claims not captured by IQVIA and SHA (doesn’t capture Medicare Advantage volume) ‣ ~2 month data lag exists with SolutionsRx data ‣ SolutionsRx (Med B / DME) used in combination with IQVIA XPO (Retail) to get ‘Total Community’ and calculate market share ‣ Only includes ~33% of YUPELRI ‘Total Community’ volume ‣ Useful for insights into directional trend of total community and is more real - time with little lag ‣ IQVIA NPA’s mail channel projections for YUPELRI are typically overstated; SHA’s methodology has been more consistent and reliable DME channel hinders visibility into tracking performance Traditional ‘Retail’ data vendors do not fully capture DME volume DME , durable medical equipment. 12 Wholesalers DMEs Retail / Mail Pharmacies Non - Retail (e.g., Hospitals) Ex - Factory Shipments Captured by IQVIA & SHA Prescription Data Not Fully Captured by IQVIA & SHA Prescription Data Hospital Purchases Captured by IQVIA DDD Total Community YUPELRI ® Product Flow

Educating health - care providers via publications 1. Tashkin DP, Barjaktarevic IZ. Chronic Obstr Pulm Dis 2020;7:136 - 8. 2. Hess MW. Int J Chron Obstruct Pulmon Dis 2020;15:2101 - 2. 3. Woods JA. J Am Pharm Assoc 2021;61:e55 - 6. 4. Sethi S, et al. Ther Adv Respir Dis 2020;14:1753466620954366. AGI, aerosol - generating procedures; MDI, metered dose inhalers. Publication Audience Summary Nebulized Treatments and the Possible Risk of Coronavirus Transmission: Where is the Evidence? 1 Pulmonology “The data should not lead to the conclusion that AGP’s are without risk but point out the need to have a balanced approach towards the use of nebulizers.” Nebulized Therapy in the COVID - 19 Era: The Right Tool for the Right Patient 2 Respiratory therapists At a time when public health information is in a state of rapid flux, rather than using a “one size fits all” policy , the more sensible approach would be to use “the right tool for the right patient” strategy based on what we know. Thus, nebulizers may remain the preferred option for some patients who require this treatment, especially in light of the severe shortage of MDIs. This approach does not conflict with recent COVID - 19 guidance Evidence - based treatment during the SARS - CoV - 2 pandemic: Identifying the knowns and unknowns of nebulization 3 Pharmacy Lack of evidence to suggest that nebulization can transmit viral particles. HCPs across all settings should take the necessary precautions to minimize the risk of infection The use of nebulized pharmacotherapies during the COVID - 19 pandemic 4 All HCPs Challenges the data currently available on nebulization and viral transmission Publications pending from Nebulization Task Force clinical research 1) Porcine Lung Model on Nebulization 2) Fluorescent visualization during nebulization 3) Measure of viral spread in COVID - 19 patients 13

About YUPELRI ® ( revefenacin ) inhalation solution YUPELRI ® ( revefenacin ) inhalation solution is a once - daily nebulized LAMA approved for the maintenance treatment of COPD in the US . Market research by Theravance Biopharma indicates approximately 9 % of the treated COPD patients in the US use nebulizers for ongoing maintenance therapy . 1 LAMAs are a cornerstone of maintenance therapy for COPD and YUPELRI ® is positioned as the first once - daily single - agent bronchodilator product for COPD patients who require, or prefer, nebulized therapy . YUPELRI ® ’s stability in both metered dose inhaler and dry powder device formulations suggest that this LAMA could also serve as a foundation for novel handheld combination products . 1. TBPH market research (N=160 physicians); refers to US COPD patients. COPD, chronic obstructive pulmonary disease; LAMA, long - acting muscarinic antagonist. 14

YUPELRI ® ( revefenacin ) inhalation solution YUPELRI ® inhalation solution is indicated for the maintenance treatment of patients with chronic obstructive pulmonary disease (COPD) . Important Safety Information (US) YUPELRI is contraindicated in patients with hypersensitivity to revefenacin or any component of this product . YUPELRI should not be initiated in patients during acutely deteriorating or potentially life - threatening episodes of COPD, or for the relief of acute symptoms, i . e . , as rescue therapy for the treatment of acute episodes of bronchospasm . Acute symptoms should be treated with an inhaled short - acting beta 2 - agonist . As with other inhaled medicines, YUPELRI can produce paradoxical bronchospasm that may be life - threatening . If paradoxical bronchospasm occurs following dosing with YUPELRI, it should be treated immediately with an inhaled, short - acting bronchodilator . YUPELRI should be discontinued immediately and alternative therapy should be instituted . YUPELRI should be used with caution in patients with narrow - angle glaucoma . Patients should be instructed to immediately consult their healthcare provider if they develop any signs and symptoms of acute narrow - angle glaucoma, including eye pain or discomfort, blurred vision, visual halos or colored images in association with red eyes from conjunctival congestion and corneal edema . Worsening of urinary retention may occur . Use with caution in patients with prostatic hyperplasia or bladder - neck obstruction and instruct patients to contact a healthcare provider immediately if symptoms occur . Immediate hypersensitivity reactions may occur after administration of YUPELRI . If a reaction occurs, YUPELRI should be stopped at once and alternative treatments considered . The most common adverse reactions occurring in clinical trials at an incidence greater than or equal to 2 % in the YUPELRI group, and higher than placebo, included cough, nasopharyngitis, upper respiratory infection, headache and back pain . Coadministration of anticholinergic medicines or OATP 1 B 1 and OATP 1 B 3 inhibitors with YUPELRI is not recommended . YUPELRI is not recommended in patients with any degree of hepatic impairment . OATP, organic anion transporting polypeptide. 15

XML

Cover	Jan. 10, 2022
Cover [Abstract]
Document Type	8-K
Amendment Flag	false
Document Period End Date	Jan. 10, 2022
Entity File Number	001-36033
Entity Registrant Name	THERAVANCE BIOPHARMA, INC.
Entity Central Index Key	0001583107
Entity Tax Identification Number	00-0000000
Entity Incorporation, State or Country Code	E9
Entity Address, Address Line One	PO Box 309
Entity Address, Address Line Two	Ugland House, South Church Street
Entity Address, City or Town	George Town, Grand Cayman
Entity Address, Country	KY
Entity Address, Postal Zip Code	KY1-1104
City Area Code	650
Local Phone Number	808-6000
Written Communications	false
Soliciting Material	false
Pre-commencement Tender Offer	false
Pre-commencement Issuer Tender Offer	false
Title of 12(b) Security	Ordinary Share $0.00001 Par Value
Trading Symbol	TBPH
Security Exchange Name	NASDAQ
Entity Emerging Growth Company	false