The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
ACER THERAPEUTICS INC COM 00444P108 2,360 109,270 SH   SOLE   109,270 0 0
AERIE PHARMACEUTICALS INC COM 00771V108 4,122 61,000 SH Put SOLE   61,000 0 0
ALIMERA SCIENCES INC COM 016259103 953 974,318 SH   SOLE   974,318 0 0
AMAG PHARMACEUTICALS INC COM 00163U106 975 50,000 SH Put SOLE   50,000 0 0
APELLIS PHARMACEUTICALS INC COM 03753U106 3,696 168,000 SH   SOLE   168,000 0 0
ARGENX SE SPONSORED ADR 04016X101 37,555 453,233 SH   SOLE   453,233 0 0
ARROWHEAD PHARMACEUTICALS IN COM 04280A100 14,012 1,030,330 SH   SOLE   1,030,330 0 0
ARROWHEAD PHARMACEUTICALS IN COM 04280A100 2,720 200,000 SH Call SOLE   0 0 0
ASCENDIS PHARMA A S SPONSORED ADR 04351P101 20,695 311,111 SH   SOLE   311,111 0 0
ASSEMBLY BIOSCIENCES INC COM 045396108 45,562 1,162,000 SH   SOLE   1,162,000 0 0
ASSEMBLY BIOSCIENCES INC COM 045396108 5,783 147,500 SH Call SOLE   0 0 0
BIOHAVEN PHARMACTL HLDG CO L COM G11196105 6,323 160,000 SH   SOLE   160,000 0 0
BIOHAVEN PHARMACTL HLDG CO L COM G11196105 2,126 53,800 SH Call SOLE   0 0 0
CAS MED SYS INC COM PAR 124769209 10,264 5,263,508 SH   SOLE   5,263,508 0 0
CATALYST BIOSCIENCES INC COM NEW 14888D208 9,686 830,000 SH   SOLE   830,000 0 0
CHEMBIO DIAGNOSTICS INC COM NEW 163572209 22,539 2,030,533 SH   SOLE   2,030,533 0 0
COHERUS BIOSCIENCES INC COM 19249H103 4,830 345,000 SH   SOLE   345,000 0 0
COHERUS BIOSCIENCES INC COM 19249H103 700 50,000 SH Call SOLE   0 0 0
CUTERA INC COM 232109108 4,232 105,000 SH   SOLE   105,000 0 0
DEUTSCHE BANK AG NAMEN AKT D18190898 1,593 150,000 SH Put SOLE   150,000 0 0
EDITAS MEDICINE INC COM 28106W103 1,792 50,000 SH Call SOLE   0 0 0
ESPERION THERAPEUTICS INC NE COM 29664W105 980 25,000 SH Put SOLE   25,000 0 0
FENNEC PHARMACEUTICALS INC COM 31447P100 2,610 250,000 SH   SOLE   250,000 0 0
FORTY SEVEN INC COM 34983P104 1,168 73,000 SH   SOLE   73,000 0 0
IMMUNOMEDICS INC COM 452907108 112,433 4,750,000 SH   SOLE   4,750,000 0 0
INOTEK PHARMACEUTICALS CORP NOTE 5.750% 8/0 45780VAB8 3,022 3,000,000 SH   SOLE   3,000,000 0 0
INTEC PHARMA LTD JERUSALEM SHS M53644106 13,035 2,962,568 SH   SOLE   2,962,568 0 0
IOVANCE BIOTHERAPEUTICS INC COM 462260100 51,520 4,025,000 SH   SOLE   4,025,000 0 0
IOVANCE BIOTHERAPEUTICS INC COM 462260100 2,432 190,000 SH Call SOLE   0 0 0
IRIDEX CORP COM 462684101 13,920 2,000,000 SH   SOLE   2,000,000 0 0
ISHARES TR MSCI EMG MKT ETF 464287234 6,500 150,000 SH Put SOLE   150,000 0 0
KADMON HLDGS INC COM 48283N106 36,149 9,060,014 SH   SOLE   9,060,014 0 0
KEZAR LIFE SCIENCES INC COM 49372L100 1,730 100,000 SH   SOLE   100,000 0 0
MADRIGAL PHARMACEUTICALS INC COM 558868105 9,734 34,803 SH   SOLE   34,803 0 0
MAGENTA THERAPEUTICS INC COM 55910K108 2,295 170,000 SH   SOLE   170,000 0 0
MANNKIND CORP COM NEW 56400P706 204 107,500 SH Put SOLE   107,500 0 0
MEI PHARMA INC COM NEW 55279B202 3,468 880,087 SH   SOLE   880,087 0 0
OBSEVA SA COM H5861P103 6,424 424,300 SH   SOLE   424,300 0 0
ONCOBIOLOGICS INC COM 68235M105 25 29,082 SH   SOLE   29,082 0 0
ORASURE TECHNOLOGIES INC COM 68554V108 824 50,000 SH Put SOLE   50,000 0 0
POLARITYTE INC COM 731094108 589 25,000 SH Put SOLE   25,000 0 0
REGENERON PHARMACEUTICALS COM 75886F107 6,900 20,000 SH Put SOLE   20,000 0 0
ROCKWELL MED INC COM 774374102 123 25,000 SH Put SOLE   25,000 0 0
SAREPTA THERAPEUTICS INC COM 803607100 7,931 60,000 SH   SOLE   60,000 0 0
SPDR SERIES TRUST S&P BIOTECH 78464A870 9,519 100,000 SH Put SOLE   100,000 0 0
STAAR SURGICAL CO COM PAR $0.01 852312305 775 25,000 SH Put SOLE   25,000 0 0
TESARO INC COM 881569107 2,224 50,000 SH   SOLE   50,000 0 0
TRANSENTERIX INC COM NEW 89366M201 109 25,000 SH Put SOLE   25,000 0 0
VERACYTE INC COM 92337F107 24,846 2,660,210 SH   SOLE   2,660,210 0 0
VERICEL CORP COM 92346J108 1,844 190,055 SH   SOLE   190,055 0 0
VIEWRAY INC COM 92672L107 10,345 1,495,000 SH   SOLE   1,495,000 0 0
VIKING THERAPEUTICS INC COM 92686J106 7,118 750,000 SH   SOLE   750,000 0 0
VIVEVE MED INC COM NEW 92852W204 728 267,500 SH   SOLE   267,500 0 0
XENON PHARMACEUTICALS INC COM 98420N105 4,140 450,000 SH   SOLE   450,000 0 0
ZAFGEN INC COM 98885E103 2,558 250,000 SH   SOLE   250,000 0 0
ZOGENIX INC COM NEW 98978L204 4,884 110,500 SH   SOLE   110,500 0 0
ZOGENIX INC COM NEW 98978L204 3,647 82,500 SH Call SOLE   0 0 0
ZOGENIX INC COM NEW 98978L204 1,989 45,000 SH Put SOLE   45,000 0 0
ZYNERBA PHARMACEUTICALS INC COM 98986X109 487 50,000 SH Put SOLE   50,000 0 0