The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
ACADIA PHARMACEUTICALS INC COM 004225108 2,792 85,999 SH   SOLE   85,999 0 0
AKARI THERAPEUTICS PLC SPONSORED ADR 00972G108 446 33,077 SH   SOLE   33,077 0 0
AKEBIA THERAPEUTICS INC COM 00972D105 4,488 600,000 SH   SOLE   600,000 0 0
ALIMERA SCIENCES INC COM 016259103 1,198 974,318 SH   SOLE   974,318 0 0
ALLERGAN PLC SHS G0177J108 1,964 8,500 SH   SOLE   8,500 0 0
AMICUS THERAPEUTICS INC COM 03152W109 6,342 1,161,545 SH   SOLE   1,161,545 0 0
ASCENDIS PHARMA A S SPONSORED ADR 04351P101 6,274 472,800 SH   SOLE   472,800 0 0
ASSEMBLY BIOSCIENCES INC COM 045396108 1,251 225,444 SH   SOLE   225,444 0 0
ATRICURE INC COM 04963C209 1,596 112,923 SH   SOLE   112,923 0 0
AUDIOCODES LTD ORD M15342104 189 45,035 SH   SOLE   45,035 0 0
BIOMARIN PHARMACEUTICAL INC COM 09061G101 4,979 64,000 SH   SOLE   64,000 0 0
BIOTELEMETRY INC COM 090672106 564 34,630 SH   SOLE   34,630 0 0
CAREDX INC COM 14167L103 279 64,627 SH   SOLE   64,627 0 0
CAS MED SYS INC COM PAR $0.004 124769209 6,441 3,500,602 SH   SOLE   3,500,602 0 0
CEMPRA INC COM 15130J109 3,463 210,000 SH   SOLE   210,000 0 0
CHEMBIO DIAGNOSTICS INC COM NEW 163572209 100 12,180 SH   SOLE   12,180 0 0
COMBIMATRIX CORPORATION COM PAR 20009T501 136 47,431 SH   SOLE   47,431 0 0
CYNAPSUS THERAPEUTICS INC COM PAR NO PAR 23257Y859 1,933 115,400 SH   SOLE   115,400 0 0
CYTOKINETICS INC COM NEW 23282W605 1,338 140,969 SH   SOLE   140,969 0 0
CYTRX CORP COM PAR $.001 232828509 223 100,000 SH Put SOLE   100,000 0 0
DERMIRA INC COM 24983L104 4,973 170,000 SH   SOLE   170,000 0 0
DEXTERA SURGICAL INC COM 252366109 232 128,958 SH   SOLE   128,958 0 0
EDGE THERAPEUTICS INC COM 279870109 5,358 530,000 SH   SOLE   530,000 0 0
ESSA PHARMA INC COM 29668H104 1,754 570,232 SH   SOLE   570,232 0 0
EVERYDAY HEALTH INC COM 300415106 7,447 945,000 SH   SOLE   945,000 0 0
GENOMIC HEALTH INC COM 37244C101 1,264 48,800 SH   SOLE   48,800 0 0
IGNYTA INC COM 451731103 1,245 229,748 SH   SOLE   229,748 0 0
IMMUNOMEDICS INC COM 452907108 9,744 4,200,000 SH   SOLE   4,200,000 0 0
IMMUNOMEDICS INC NOTE 4.750% 2/1 452907AK4 3,733 5,500,000 PRN   SOLE   0 0 5,500,000
IMMUNOMEDICS INC COM 452907108 136 58,600 SH Call SOLE   0 0 0
INNOCOLL HLDGS PLC SHS G4783X105 3,130 568,137 SH   SOLE   568,137 0 0
INSMED INC COM PAR $.01 457669307 2,169 220,000 SH   SOLE   220,000 0 0
INSULET CORP COM 45784P101 2,268 75,000 SH   SOLE   75,000 0 0
IRIDEX CORP COM 462684101 14,966 1,011,871 SH   SOLE   1,011,871 0 0
IRONWOOD PHARMACEUTICALS INC COM CL A 46333X108 654 50,000 SH   SOLE   50,000 0 0
ISHARES TR RUSSELL 2000 ETF 464287655 5,749 50,000 SH Put SOLE   50,000 0 0
LION BIOTECHNOLOGIES INC COM 53619R102 26,183 3,232,416 SH   SOLE   3,232,416 0 0
MANNKIND CORP COM 56400P201 104 90,000 SH Put SOLE   90,000 0 0
MARVELL TECHNOLOGY GROUP LTD ORD G5876H105 2,283 239,588 SH   SOLE   239,588 0 0
MEDIVATION INC COM 58501N101 3,015 50,000 SH   SOLE   50,000 0 0
MIRATI THERAPEUTICS INC COM 60468T105 683 125,000 SH   SOLE   125,000 0 0
NABRIVA THERAPEUTICS AG SPONSORED ADR 62957M104 4,191 558,771 SH   SOLE   558,771 0 0
NEUROCRINE BIOSCIENCES INC COM 64125C109 1,909 42,000 SH   SOLE   42,000 0 0
NEURODERM LTD ORD SHS M74231107 10,303 634,000 SH   SOLE   634,000 0 0
ONCOBIOLOGICS INC COM 68235M105 828 243,391 SH   SOLE   243,391 0 0
ONCOBIOLOGICS INC *W EXP 02/18/201 68235M113 45 96,833 SH   SOLE   96,833 0 0
ONCOBIOLOGICS INC *W EXP 05/18/201 68235M121 44 96,833 SH   SOLE   96,833 0 0
OXFORD IMMUNOTEC GLOBAL PLC ORD SHS G6855A103 3,756 417,278 SH   SOLE   417,278 0 0
PACIFIC BIOSCIENCES CALIF IN COM 69404D108 2,111 300,000 SH   SOLE   300,000 0 0
PERNIX THERAPEUTICS HLDGS IN COM 71426V108 28 62,800 SH Put SOLE   62,800 0 0
PROGENICS PHARMACEUTICALS IN COM 743187106 1,894 448,885 SH   SOLE   448,885 0 0
RAPTOR PHARMACEUTICAL CORP COM 75382F106 938 174,708 SH   SOLE   174,708 0 0
RELYPSA INC COM 759531106 185 10,000 SH Call SOLE   0 0 0
RETROPHIN INC COM 761299106 1,759 98,788 SH   SOLE   98,788 0 0
RIGEL PHARMACEUTICALS INC COM NEW 766559603 1,667 747,748 SH   SOLE   747,748 0 0
RR MEDIA LTD SHS M8183P102 7,996 611,818 SH   SOLE   611,818 0 0
SAREPTA THERAPEUTICS INC COM 803607100 2,479 130,000 SH   SOLE   130,000 0 0
SAREPTA THERAPEUTICS INC COM 803607100 1,526 80,000 SH Call SOLE   0 0 0
SINOVAC BIOTECH LTD SHS P8696W104 786 132,503 SH   SOLE   132,503 0 0
STONE ENERGY CORP COM NEW 861642304 1,304 108,100 SH Put SOLE   108,100 0 0
TESARO INC COM 881569107 2,522 30,000 SH   SOLE   30,000 0 0
TROVAGENE INC COM NEW 897238309 236 52,000 SH Put SOLE   52,000 0 0
UNIVERSAL DISPLAY CORP COM 91347P105 1,017 15,000 SH   SOLE   15,000 0 0
VERACYTE INC COM 92337F107 16,034 3,187,607 SH   SOLE   3,187,607 0 0
WEBMD HEALTH CORP COM 94770V102 1,453 25,000 SH   SOLE   25,000 0 0