Related Parties (Details) - shares	Mar. 23, 2018	Mar. 07, 2018
Teva Pharmaceuticals International GmbH and Teva Canada Limited [Member]
Related Party Transaction [Line Items]
Collaborative development and license agreement termination date		Mar. 07, 2018
Teva Pharmaceuticals International GmbH and Teva Canada Limited [Member] | Minimum [Member]
Related Party Transaction [Line Items]
Percentage of ownership		5.00%
Teva Canada Limited [Member]
Related Party Transaction [Line Items]
Number of common shares agreed to transfer and assign for cancellation		1,000,000
BVF Partners L.P [Member] | Exchange Agreement [Member]
Related Party Transaction [Line Items]
Percentage of ownership	19.90%
BVF Partners L.P [Member] | Exchange Agreement [Member] | Series1 Preferred Shares
Related Party Transaction [Line Items]
Stock Issued	2,868,000
Common stock received in exchange of preferred shares	2,868,000