As filed with the Securities and Exchange Commission on August 1, 2014
Registration No. 333-
UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM S-8
REGISTRATION STATEMENT UNDER THE SECURITIES ACT OF 1933
LOXO ONCOLOGY, INC.
(Exact Name of Registrant as Specified in Its Charter)
Delaware |
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46-2996673 |
(State or Other Jurisdiction |
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(I.R.S. Employer |
Loxo Oncology, Inc.
One Landmark Square
Suite 1122
Stamford, CT 06901
(Address of Principal Executive Offices) (Zip Code)
2013 Equity Incentive Plan
2014 Equity Incentive Plan
2014 Employee Stock Purchase Plan
(Full Title of the Plans)
Joshua H. Bilenker, M.D.
President and Chief Executive Officer
Loxo Oncology, Inc.
One Landmark Square
Suite 1122
Stamford, CT 06901
(Name and Address of Agent for Service)
(203) 653-3880
(Telephone Number, including area code, of agent for service)
Copies to:
Robert A. Freedman, Esq.
Fenwick & West LLP
Silicon Valley Center
801 California Street
Mountain View, California 94041
(650) 988-8500
Indicate by check mark whether the Registrant is a large accelerated filer, an accelerated filer, a non-accelerated filer, or a smaller reporting company. See definitions of large accelerated filer, accelerated filer, and smaller reporting company in Rule 12b-2 of the Exchange Act. (Check one):
Large accelerated filer ¨ |
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Accelerated filer ¨ |
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Non-accelerated filer x |
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Smaller reporting company ¨ |
CALCULATION OF REGISTRATION FEE
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Title of Securities |
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Amount To Be |
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Proposed Maximum |
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Proposed Maximum |
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Amount of |
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Common Stock, $0.0001 par value per share |
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Outstanding under the 2013 Equity Incentive Plan |
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1,419,619 |
(2) |
$ |
3.02 |
(3) |
$ |
4,287,249 |
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$ |
553 |
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Outstanding under the 2014 Equity Incentive Plan |
|
78,125 |
(4) |
$ |
13.00 |
(5) |
$ |
1,015,625 |
|
$ |
131 |
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Reserved for issuance under the 2014 Equity Incentive Plan |
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1,013,960 |
(6) |
$ |
13.00 |
(7) |
$ |
13,181,480 |
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$ |
1,698 |
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Reserved for issuance under the 2014 Employee Stock Purchase Plan |
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149,600 |
(8) |
$ |
11.05 |
(7) |
$ |
1,653,080 |
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$ |
213 |
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TOTAL |
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2,661,304 |
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N/A |
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$ |
20,137,434 |
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$ |
2,595 |
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(1) Pursuant to Rule 416(a) under the Securities Act of 1933, as amended (the Securities Act), this Registration Statement shall also cover any additional shares of the Registrants Common Stock that become issuable under the Registrants 2013 Equity Incentive Plan (the 2013 Plan), 2014 Equity Incentive Plan (the 2014 Plan), and 2014 Employee Stock Purchase Plan (the 2014 ESPP) by reason of any stock dividend, stock split, recapitalization or other similar transaction effected without the Registrants receipt of consideration that increases the number of the outstanding shares of the Registrants Common Stock.
(2) Represents shares subject to issuance upon the exercise of stock options outstanding under the 2013 Plan as of the date of this Registration Statement. To the extent outstanding stock options under the 2013 Plan are forfeited or lapse unexercised and the shares that were subject to issuance upon the exercise of such stock options would otherwise have been returned to the share reserve under the 2013 Plan, the shares of Common Stock subject to such stock options instead will be available for future issuance under the 2014 Plan. See footnote 4 below.
(3) Estimated solely for the purpose of calculating the registration fee in accordance with Rule 457(h) under the Securities Act on the basis of the weighted average exercise price of $3.02 per share (rounded up to the nearest cent).
(4) Represents shares of common stock reserved for issuance pursuant to stock options outstanding under the 2014 Plan as of the date of this Registration Statement.
(5) Estimated solely for the purpose of calculating the registration fee in accordance with Rule 457(h) under the Securities Act on the basis of the exercise price of $13.00 per share.
(6) Shares of common stock reserved for future issuance under the 2014 Plan consist of (a) 1,013,960 shares of common stock reserved for future issuance under the 2014 Plan and (b) no shares of common stock previously reserved but unissued under the 2013 Plan that are now available for future issuance under the 2014 Plan. To the extent outstanding awards under the 2013 Plan are forfeited, lapse unexercised or would otherwise have been returned to the share reserve under the 2013 Plan, the shares of common stock subject to such awards instead will be available for future issuance under the 2014 Plan. See footnote 2 above.
(7) Calculated solely for the purposes of this offering under Rule 457(h) of the Securities Act on the basis of the initial public offering price per share of the Registrants Common Stock as set forth in the Registrants prospectus filed with the Securities and Exchange Commission on August 1, 2014 pursuant to Rule 424(b) under the Securities Act. In the case of the 2014 ESPP, this price per share is multiplied by 85%, which is the percentage of the price per share applicable to purchases under the 2014 ESPP.
(8) Represents shares reserved for issuance under the 2014 ESPP as of the date of this Registration Statement.
PART I
Information Required in the Section 10(a) Prospectus
The information called for by Part I of Form S-8 is omitted from this Registration Statement in accordance with Rule 428 of the Securities Act of 1933, as amended (the Securities Act), and the instructions to Form S-8. In accordance with the rules and regulations of the Securities and Exchange Commission (the Commission) and the instructions to Form S-8, such documents are not being filed with the Commission either as part of this Registration Statement or as prospectuses or prospectus supplements pursuant to Rule 424 under the Securities Act.
PART II
Information Required in the Registration Statement
Item 3. Incorporation of Documents by Reference.
The Registrant hereby incorporates by reference into this Registration Statement the following documents previously filed with the Commission:
(a) the Registrants prospectus dated July 31, 2014 and filed on August 1, 2014 pursuant to Rule 424(b) under the Securities Act relating to the Registration Statement on Form S-1, as amended (Registration No. 333-197123) (the Form S-1), which contains audited financial statements for the Registrants latest fiscal year for which such statements have been filed; and
(b) the description of the Registrants Common Stock contained in the Registrants Registration Statement on Form 8-A (Registration No. 001-36562) filed with the Commission on July 22, 2014, including any amendments or reports filed for the purpose of updating such description.
All reports and definitive proxy or information statements filed by the Registrant pursuant to Section 13(a), 13(c), 14 or 15(d) of the Securities Exchange Act of 1934, as amended (the Exchange Act) subsequent to the filing of this Registration Statement and prior to the filing of a post-effective amendment which indicates that all securities offered hereby have been sold or which de-registers all securities then remaining unsold shall be deemed to be incorporated by reference into this Registration Statement and to be a part hereof from the date of filing of such documents, except as to documents or information deemed to have been furnished and not filed in accordance with the rules of the Commission. Any statement contained in a document incorporated or deemed to be incorporated by reference herein shall be deemed to be modified or superseded for purposes of this Registration Statement to the extent that a statement contained in any subsequently filed document which also is deemed to be incorporated by reference herein modifies or supersedes such statement.
Item 4. Description of Securities.
Not applicable.
Item 5. Interests of Named Experts and Counsel.
Not applicable.
Item 6. Indemnification of Directors and Officers.
Section 145 of the Delaware General Corporation Law authorizes a court to award or the Board of Directors of a corporation to grant indemnity to directors and officers in terms sufficiently broad to permit indemnification (including reimbursement of expenses incurred) under certain circumstances for liabilities arising under the Securities Act.
As permitted by the Delaware General Corporation Law, the restated certificate of incorporation of the Registrant contains provisions that eliminate the personal liability of its directors for monetary damages for any breach of fiduciary duties as a director, to the fullest extent permitted by law.
As permitted by the Delaware General Corporation Law, the restated bylaws of the Registrant provide that (i) the Registrant is required to indemnify its directors and executive officers to the fullest extent permitted by the Delaware General Corporation Law, subject to very limited exceptions; (ii) the Registrant may enter into indemnification contracts with any director, officer, employee or agent of the Registrant; (iii) the Registrant is required to advance expenses, as incurred, to its directors and executive officers in connection with a legal proceeding to the fullest extent permitted by the Delaware General Corporation Law, subject to very limited exceptions; and (iv) the rights conferred in the restated bylaws are not exclusive.
In addition, the Registrant has entered into indemnification agreements with each of its current directors and executive officers to provide them with additional contractual assurances regarding the scope of the
indemnification set forth in the Registrants restated certificate of incorporation and restated bylaws and to provide additional procedural protections. At present, there is no pending litigation or proceeding involving a director, officer or employee of the Registrant regarding which indemnification is sought, nor is the Registrant aware of any threatened litigation that may result in claims for indemnification.
The Registrant currently carries liability insurance for its directors and officers.
Reference is also made to the Underwriting Agreement filed with the Form S-1 for the Registrants initial public offering, which provides for the indemnification of officers, directors and controlling persons of the Registrant against certain liabilities.
The indemnification provision in the Registrants restated certificate of incorporation and restated bylaws and the indemnification agreements entered into between the Registrant and each of its directors and executive officers may be sufficiently broad to permit indemnification of the Registrants directors and officers for liabilities arising under the Securities Act.
See also the undertakings set out in response to Item 9 of this Registration Statement.
Item 7. Exemption from Registration Claimed.
Not applicable.
Item 8. Exhibits.
Exhibit |
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Incorporated by Reference |
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Filed | ||||||
Number |
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Exhibit Description |
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Form |
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File No. |
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Exhibit |
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Filing Date |
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Herewith |
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4.1 |
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Restated Certificate of Incorporation of the Registrant, as amended to date. |
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S-1 |
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333-197123 |
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3.1 |
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July 21, 2014 |
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4.2 |
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Form of Restated Certificate of Incorporation of the Registrant, to be filed immediately after the closing of the offering covered by the Form S-1. |
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S-1 |
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333-197123 |
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3.2 |
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July 21, 2014 |
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4.3 |
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Bylaws of the Registrant, as currently in effect. |
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S-1 |
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333-197123 |
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3.3 |
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June 30, 2014 |
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4.4 |
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Form of Restated Bylaws of the Registrant, to be effective immediately after the closing of the offering covered by the Form S-1. |
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S-1 |
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333-197123 |
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3.4 |
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July 21, 2014 |
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4.5 |
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2013 Equity Incentive Plan and forms of award agreements. |
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S-1 |
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333-197123 |
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10.2 |
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July 30, 2014 |
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4.6 |
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2014 Equity Incentive Plan and forms of award agreements. |
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S-1 |
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333-197123 |
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10.3 |
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July 21, 2014 |
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4.7 |
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2014 Employee Stock Purchase Plan |
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S-1 |
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333-197123 |
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10.9 |
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July 21, 2014 |
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5.1 |
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Opinion and Consent of Fenwick & West LLP. |
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X |
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23.1 |
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Consent of CohnReznick LLP, independent registered public accounting firm. |
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X |
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23.2 |
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Consent of Fenwick & West LLP (contained in Exhibit 5.1). |
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X |
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24.1 |
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Power of Attorney (incorporated by reference to Page II-4 of this Registration Statement). |
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X |
Item 9. Undertakings.
A. The undersigned Registrant hereby undertakes:
(1) To file, during any period in which offers or sales are being made, a post-effective amendment to this Registration Statement:
(i) To include any prospectus required by Section 10(a)(3) of the Securities Act;
(ii) To reflect in the prospectus any facts or events arising after the effective date of the Registration Statement (or the most recent post-effective amendment thereof) which, individually or in the aggregate, represent a fundamental change in the information set forth in the Registration Statement. Notwithstanding the foregoing, any increase or decrease in volume of securities offered (if the total dollar value of securities offered would not exceed that which was registered) and any deviation from the low or high end of the estimated maximum offering range may be reflected in the form of prospectus filed with the Commission pursuant to Rule 424(b) if, in the aggregate, the changes in volume and price represent no more than a 20 percent change in the maximum aggregate offering price set forth in the Calculation of Registration Fee table in the effective Registration Statement;
(iii) To include any material information with respect to the plan of distribution not previously disclosed in the Registration Statement or any material change to such information in the Registration Statement;
Provided, however, that paragraphs (a)(1)(i) and (a)(1)(ii) above do not apply if the information required to be included in a post-effective amendment by those paragraphs is contained in periodic reports filed with or furnished to the Commission by the Registrant pursuant to Section 13 or Section 15(d) of the Exchange Act that are incorporated by reference in the Registration Statement.
(2) That, for the purpose of determining any liability under the Securities Act, each such post-effective amendment shall be deemed to be a new registration statement relating to the securities offered therein, and the offering of such securities at that time shall be deemed to be the initial bona fide offering thereof.
(3) To remove from registration by means of a post-effective amendment any of the securities being registered which remain unsold at the termination of the offering.
B. The undersigned Registrant hereby undertakes that, for purposes of determining any liability under the Securities Act, each filing of the Registrants annual report pursuant to Section 13(a) or Section 15(d) of the Exchange Act (and, where applicable, each filing of an employee benefit plans annual report pursuant to Section 15(d) of the Exchange Act) that is incorporated by reference in the Registration Statement shall be deemed to be a new registration statement relating to the securities offered therein, and the offering of such securities at that time shall be deemed to be the initial bona fide offering thereof.
C. Insofar as indemnification for liabilities arising under the Securities Act may be permitted to directors, officers and controlling persons of the Registrant pursuant to the foregoing provisions, or otherwise, the Registrant has been advised that in the opinion of the Commission such indemnification is against public policy as expressed in the Securities Act and is, therefore, unenforceable. In the event that a claim for indemnification against such liabilities (other than the payment by the Registrant of expenses incurred or paid by a director, officer or controlling person of the Registrant in the successful defense of any action, suit or proceeding) is asserted by such director, officer or controlling person in connection with the securities being registered, the Registrant will, unless in the opinion of its counsel the matter has been settled by controlling precedent, submit to a court of appropriate jurisdiction the question whether such indemnification by it is against public policy as expressed in the Securities Act and will be governed by the final adjudication of such issue.
SIGNATURES
Pursuant to the requirements of the Securities Act of 1933, the Registrant certifies that it has reasonable grounds to believe that it meets all of the requirements for filing on Form S-8 and has duly caused this Registration Statement to be signed on its behalf by the undersigned, thereunto duly authorized, in the City of Stamford, State of Connecticut, on this 1st day of August, 2014.
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Loxo Oncology, Inc. | |
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By: |
/s/ Joshua H. Bilenker, M.D. |
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Joshua H. Bilenker, M.D. |
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President, Chief Executive Officer and Director |
POWER OF ATTORNEY
KNOW ALL PERSONS BY THESE PRESENTS, that the undersigned officers and directors of Loxo Oncology, Inc., a Delaware corporation, do hereby constitute and appoint Joshua H. Bilenker, M.D., President, Chief Executive Officer and Director and Dov A. Goldstein, M.D., Chief Financial Officer and Director, the lawful attorneys-in-fact and agents with full power and authority to do any and all acts and things and to execute any and all instruments which said attorneys and agents, and any one of them, determine may be necessary or advisable or required to enable said corporation to comply with the Securities Act of 1933, as amended, and any rules or regulations or requirements of the Securities and Exchange Commission in connection with this Registration Statement. Without limiting the generality of the foregoing power and authority, the powers granted include the power and authority to sign the names of the undersigned officers and directors in the capacities indicated below to this Registration Statement, to any and all amendments, both pre-effective and post-effective, and supplements to this Registration Statement, and to any and all instruments or documents filed as part of or in conjunction with this Registration Statement or amendments or supplements thereof, and each of the undersigned hereby ratifies and confirms that all said attorneys and agents, or any one of them, shall do or cause to be done by virtue hereof.
IN WITNESS WHEREOF, each of the undersigned has executed this Power of Attorney as of the date indicated.
Pursuant to the requirements of the Securities Act of 1933, as amended, this Registration Statement has been signed by the following persons on behalf of the Registrant in the capacities and on the dates indicated.
Signature |
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Title |
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Date |
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/s/ Joshua H. Bilenker, M.D. |
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President, Chief Executive Officer and |
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August 1, 2014 |
Joshua H. Bilenker, M.D. |
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Director |
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(Principal Executive Officer) |
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/s/ Dov A. Goldstein, M.D. |
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Chief Financial Officer and Director |
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August 1, 2014 |
Dov A. Goldstein, M.D. |
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(Principal Financial Officer and Principal |
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Accounting Officer) |
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/s/ James Barrett, Ph.D. |
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Director |
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August 1, 2014 |
James Barrett, Ph.D. |
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/s/ David, Bonita, M.D. |
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Director |
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August 1, 2014 |
David, Bonita, M.D. |
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/s/ Steven A. Elms |
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Director |
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August 1, 2014 |
Steven A. Elms |
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/s/ Keith T. Flaherty, M.D. |
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Director |
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August 1, 2014 |
Keith T. Flaherty, M.D. |
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/s/ Avi Z. Naider |
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Director |
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August 1, 2014 |
Avi Z. Naider |
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EXHIBIT INDEX
Exhibit |
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Incorporated by Reference |
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Filed | ||||||
Number |
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Exhibit Description |
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Form |
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File No. |
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Exhibit |
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Filing Date |
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Herewith |
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4.1 |
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Restated Certificate of Incorporation of the Registrant, as amended to date. |
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S-1 |
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333-197123 |
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3.1 |
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July 21, 2014 |
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4.2 |
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Form of Restated Certificate of Incorporation of the Registrant, to be filed immediately after the closing of the offering covered by the Form S-1. |
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S-1 |
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333-197123 |
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3.2 |
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July 21, 2014 |
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4.3 |
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Bylaws of the Registrant, as currently in effect. |
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S-1 |
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333-197123 |
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3.3 |
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June 30, 2014 |
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4.4 |
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Form of Restated Bylaws of the Registrant, to be effective immediately after the closing of the offering covered by the Form S-1. |
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S-1 |
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333-197123 |
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3.4 |
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July 21, 2014 |
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4.5 |
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2013 Equity Incentive Plan and forms of award agreements. |
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S-1 |
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333-197123 |
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10.2 |
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July 30, 2014 |
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4.6 |
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2014 Equity Incentive Plan and forms of award agreements. |
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S-1 |
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333-197123 |
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10.3 |
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July 21, 2014 |
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4.7 |
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2014 Employee Stock Purchase Plan |
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S-1 |
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333-197123 |
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10.9 |
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July 21, 2014 |
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5.1 |
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Opinion and Consent of Fenwick & West LLP. |
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X |
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23.1 |
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Consent of CohnReznick LLP, independent registered public accounting firm. |
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X |
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23.2 |
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Consent of Fenwick & West LLP (contained in Exhibit 5.1). |
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X |
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24.1 |
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Power of Attorney (incorporated by reference to Page II-4 of this Registration Statement). |
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X |
Exhibit 5.1
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August 1, 2014 |
Loxo Oncology, Inc.
One Landmark Square
Suite 1122
Stamford, CT 06901
Gentlemen/Ladies:
At your request, we have examined the Registration Statement on Form S-8 (the Registration Statement) to be filed by Loxo Oncology, Inc., a Delaware corporation (the Company), with the Securities and Exchange Commission (the Commission) on or about August 1, 2014 in connection with the registration under the Securities Act of 1933, as amended, of an aggregate of 2,661,304 shares of the Companys Common Stock, $0.001 par value per share (the Stock), subject to issuance by the Company upon the exercise of (a) stock options granted under the Companys 2013 Equity Incentive Plan, which plan has been terminated and under which no further stock options will be granted, (b) stock options granted or to be granted under the Companys 2014 Equity Incentive Plan, and (c) purchase rights to be granted under the Companys 2014 Employee Stock Purchase Plan. The plans referred to in clauses (a) through (c) in the preceding sentence are collectively referred to in this letter as the Plans. In rendering this opinion, we have examined such matters of fact as we have deemed necessary in order to render the opinion set forth herein, which included examination of the following:
(1) the Companys Amended and Restated Certificate of Incorporation, certified by the Delaware Secretary of State on July 21, 2014 (the Restated Certificate);
(2) the form of the Companys Restated Certificate of Incorporation to be filed upon the closing of the offering contemplated by the registration statement on Form S-1, as amended (Registration No. 333-197123) (the Form S-1), in connection with the initial public offering of the Stock (the Post-Effective Restated Certificate);
(3) the Companys Bylaws, certified by the Companys Secretary on June 24, 2013 (the Bylaws);
(4) the form of the Companys Restated Bylaws to be effective upon the closing of the offering contemplated by the Form S-1 in connection with the initial public offering of the Stock (the Post-Effective Bylaws);
(5) the Registration Statement, together with the Exhibits filed as a part thereof or incorporated therein by reference;
(6) the Plans and related forms of Plan agreements;
August 1, 2014
(7) the prospectuses prepared in connection with the Registration Statement (the Prospectuses);
(8) the minutes of meetings and actions by written consent of the Companys Board of Directors (the Board) and stockholders at which, or pursuant to which, the Restated Certificate, Post-Effective Restated Certificate, Bylaws and Post-Effective Bylaws were approved;
(9) the minutes of meetings and actions by written consent of the Board and stockholders at which, or pursuant to which, the Board and stockholders of the Company adopted and approved the Plans, the reservation of the Stock for sale and issuance pursuant to the Plans and the filing of the Registration Statement;
(10) a statement prepared by the Company as to the number of issued and outstanding options, warrants and rights to purchase shares of the Companys capital stock and any additional shares of capital stock reserved for future issuance in connection with the Companys stock option and stock purchase plans and all other plans, agreements or rights as of July 31, 2014;
(11) a Certificate of Good Standing issued by the Secretary of State of the State of Delaware dated July 31, 2014 (the Certificate of Good Standing); and
(12) an Opinion Certificate addressed to us and dated of even date herewith executed by the Company containing certain factual representations (the Opinion Certificate).
In our examination of documents for purposes of this opinion, we have relied on the accuracy of representations to us by officers of the Company with respect to the genuineness of all signatures on original documents, the authenticity and completeness of all documents submitted to us as originals, the conformity to originals and completeness of all documents submitted to us as copies, the legal capacity of all persons or entities executing the same, the lack of any undisclosed termination, modification, waiver or amendment to any document referenced in clauses (6), (8) and (9) above to us.
The Companys capital stock is uncertificated. We assume that issued Stock will not be reissued by the Company in uncertificated form until any previously issued stock certificate representing such issued Stock have been surrendered to the Company in accordance with DGCL Section 158 and that the Company will properly register the transfer of the Stock to the purchasers of such Stock on the Companys record of uncertificated securities.
As to matters of fact relevant to this opinion, we have relied solely upon our examination of the documents referred to above and have assumed the current accuracy and completeness of the information obtained from the documents referred to above and the representations and warranties made by representatives of the Company to us, including but not limited to those set forth in the Opinion Certificate. We have made no independent investigation or other attempt to
August 1, 2014
verify the accuracy of any of such information or to determine the existence or non-existence of any other factual matters.
We render this opinion only with respect to, and express no opinion herein concerning the application or effect of the laws of any jurisdiction other than, the existing laws of the United States of America, of the State of California and of the Delaware General Corporation Law, the Delaware Constitution and reported judicial decisions relating thereto.
With respect to our opinion expressed in paragraph (1) below as to the valid existence and good standing of the Company under the laws of the State of Delaware, we have relied solely upon the Certificate of Good Standing and representations made to us by the Company.
This opinion is based upon the customary practice of lawyers who regularly give, and lawyers who regularly advise opinion recipients regarding, opinions of the kind set forth in this opinion letter, including customary practice as described in bar association reports.
Based upon the foregoing, it is our opinion that:
(1) The Company is a corporation validly existing, in good standing, under the laws of the State of Delaware; and
(2) The 2,661,304 shares of Stock that may be issued and sold by the Company upon the exercise of (a) stock options granted under the Companys 2013 Equity Incentive Plan, which plan has been terminated and under which no further stock options will be granted, (b) stock options granted or to be granted under the Companys 2014 Equity Incentive Plan, and (c) purchase rights to be granted under the Companys 2014 Employee Stock Purchase Plan, when issued, sold and delivered in accordance with the applicable Plan and purchase agreements entered into and to be entered into thereunder and in the manner and for the consideration stated in the Registration Statement and the relevant Prospectus, will be validly issued, fully paid and nonassessable.
We consent to the use of this opinion as an exhibit to the Registration Statement and further consent to all references to us, if any, in the Registration Statement, the Prospectus constituting a part thereof and any amendments thereto.
This opinion is intended solely for use in connection with issuance and sale of shares subject to the Registration Statement and is not to be relied upon for any other purpose. This opinion is rendered as of the date first written above and based solely on our understanding of facts in existence as of such date after the aforementioned examination. We assume no obligation to advise you of any fact, circumstance, event or change in the law or the facts that may hereafter be brought to our attention whether or not such occurrence would affect or modify the opinions expressed herein.
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Very truly yours, | |
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FENWICK & WEST LLP | |
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By: |
/s/ Fenwick & West LLP |
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Fenwick & West LLP |
Exhibit 23.1
Consent of Independent Registered
Public Accounting Firm
We consent to the incorporation by reference in this Registration Statement on Form S-8 of Loxo Oncology, Inc. of our report dated May 14, 2014, except for the effects of the matter discussed in Note 11, which is as of July 21, 2014, on our audit of the financial statements of Loxo Oncology, Inc. as of December 31, 2013 and for the period from May 9, 2013 (date of inception) to December 31, 2013, included in Loxo Oncology Inc.s Registration Statement on Form S-1 (Amendment No. 2).
/s/ CohnReznick LLP |
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Roseland, New Jersey |
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July 29, 2014 |
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