0001104659-14-055888.txt : 20140801 0001104659-14-055888.hdr.sgml : 20140801 20140801142125 ACCESSION NUMBER: 0001104659-14-055888 CONFORMED SUBMISSION TYPE: S-8 PUBLIC DOCUMENT COUNT: 3 FILED AS OF DATE: 20140801 DATE AS OF CHANGE: 20140801 EFFECTIVENESS DATE: 20140801 FILER: COMPANY DATA: COMPANY CONFORMED NAME: Loxo Oncology, Inc. CENTRAL INDEX KEY: 0001581720 STANDARD INDUSTRIAL CLASSIFICATION: PHARMACEUTICAL PREPARATIONS [2834] IRS NUMBER: 462996673 STATE OF INCORPORATION: DE FISCAL YEAR END: 1231 FILING VALUES: FORM TYPE: S-8 SEC ACT: 1933 Act SEC FILE NUMBER: 333-197800 FILM NUMBER: 141009509 BUSINESS ADDRESS: STREET 1: 1 LANDMARK SQUARE, SUITE 1122 CITY: STAMFORD STATE: CT ZIP: 06901 BUSINESS PHONE: 203-658-4749 MAIL ADDRESS: STREET 1: 1 LANDMARK SQUARE, SUITE 1122 CITY: STAMFORD STATE: CT ZIP: 06901 S-8 1 a14-11751_10s8.htm S-8

 

As filed with the Securities and Exchange Commission on August 1, 2014

 

Registration No. 333-               

 

 

UNITED STATES

SECURITIES AND EXCHANGE COMMISSION

Washington, D.C. 20549

 


 

FORM S-8

 

REGISTRATION STATEMENT UNDER THE SECURITIES ACT OF 1933

 


 

LOXO ONCOLOGY, INC.

(Exact Name of Registrant as Specified in Its Charter)

 

Delaware

 

46-2996673

(State or Other Jurisdiction
of Incorporation or Organization)

 

(I.R.S. Employer
Identification No.)

 

Loxo Oncology, Inc.

One Landmark Square

Suite 1122
Stamford, CT 06901

(Address of Principal Executive Offices)  (Zip Code)

 

2013 Equity Incentive Plan

2014 Equity Incentive Plan

2014 Employee Stock Purchase Plan

(Full Title of the Plans)

 


 

Joshua H. Bilenker, M.D.

President and Chief Executive Officer

Loxo Oncology, Inc.
One Landmark Square

Suite 1122
Stamford, CT 06901

(Name and Address of Agent for Service)

 

(203) 653-3880

(Telephone Number, including area code, of agent for service)

 


 

Copies to:

 

Robert A. Freedman, Esq.

Fenwick & West LLP

Silicon Valley Center

801 California Street

Mountain View, California 94041

(650) 988-8500

 


 

Indicate by check mark whether the Registrant is a large accelerated filer, an accelerated filer, a non-accelerated filer, or a smaller reporting company. See definitions of “large accelerated filer,” “accelerated filer,” and “smaller reporting company” in Rule 12b-2 of the Exchange Act. (Check one):

 

Large accelerated filer ¨

 

Accelerated filer ¨

 

 

 

Non-accelerated filer x
(Do not check if a smaller reporting company)

 

Smaller reporting company ¨

 

CALCULATION OF REGISTRATION FEE

 

 

 

 

 

 

 

 

 

 

Title of Securities
To Be Registered

 

Amount To Be
Registered (1)

 

Proposed Maximum
Offering Price
Per Share

 

Proposed Maximum
Aggregate Offering Price

 

Amount of
Registration 
Fee

 

Common Stock, $0.0001 par value per share

 

 

 

 

 

 

 

 

 

  — Outstanding under the 2013 Equity Incentive Plan

 

1,419,619

(2)

$

3.02

(3)

$

4,287,249

 

$

553

 

  — Outstanding under the 2014 Equity Incentive Plan

 

78,125

(4)

$

13.00

(5)

$

1,015,625

 

$

131

 

  — Reserved for issuance under the 2014 Equity Incentive Plan

 

1,013,960

(6)

$

13.00

(7)

$

13,181,480

 

$

1,698

 

  — Reserved for issuance under the 2014 Employee Stock Purchase Plan

 

149,600

(8)

$

11.05

(7)

$

1,653,080

 

$

213

 

TOTAL

 

2,661,304

 

 

N/A

 

$

20,137,434

 

$

2,595

 

(1)             Pursuant to Rule 416(a) under the Securities Act of 1933, as amended (the “Securities Act”), this Registration Statement shall also cover any additional shares of the Registrant’s Common Stock that become issuable under the Registrant’s 2013 Equity Incentive Plan (the “2013 Plan”), 2014 Equity Incentive Plan (the “2014 Plan”), and 2014 Employee Stock Purchase Plan (“the 2014 ESPP”)  by reason of any stock dividend, stock split, recapitalization or other similar transaction effected without the Registrant’s receipt of consideration that increases the number of the outstanding shares of the Registrant’s Common Stock.

 

(2)             Represents shares subject to issuance upon the exercise of stock options outstanding under the 2013 Plan as of the date of this Registration Statement.  To the extent outstanding stock options under the 2013 Plan are forfeited or lapse unexercised and the shares that were subject to issuance upon the exercise of such stock options would otherwise have been returned to the share reserve under the 2013 Plan, the shares of Common Stock subject to such stock options instead will be available for future issuance under the 2014 Plan. See footnote 4 below.

 

(3)             Estimated solely for the purpose of calculating the registration fee in accordance with Rule 457(h) under the Securities Act on the basis of the weighted average exercise price of $3.02 per share (rounded up to the nearest cent).

 

(4)             Represents shares of common stock reserved for issuance pursuant to stock options outstanding under the 2014 Plan as of the date of this Registration Statement.

 

(5)             Estimated solely for the purpose of calculating the registration fee in accordance with Rule 457(h) under the Securities Act on the basis of the exercise price of $13.00 per share.

 

(6)             Shares of common stock reserved for future issuance under the 2014 Plan consist of (a) 1,013,960 shares of common stock reserved for future issuance under the 2014 Plan and (b) no shares of common stock previously reserved but unissued under the 2013 Plan that are now available for future issuance under the 2014 Plan. To the extent outstanding awards under the 2013 Plan are forfeited, lapse unexercised or would otherwise have been returned to the share reserve under the 2013 Plan, the shares of common stock subject to such awards instead will be available for future issuance under the 2014 Plan. See footnote 2 above.

 

(7)            Calculated solely for the purposes of this offering under Rule 457(h) of the Securities Act on the basis of the initial public offering price per share of the Registrant’s Common Stock as set forth in the Registrant’s prospectus filed with the Securities and Exchange Commission on August 1, 2014 pursuant to Rule 424(b) under the Securities Act. In the case of the 2014 ESPP, this price per share is multiplied by 85%, which is the percentage of the price per share applicable to purchases under the 2014 ESPP.

 

(8)             Represents shares reserved for issuance under the 2014 ESPP as of the date of this Registration Statement.

 

 

 



 

PART I

 

Information Required in the Section 10(a) Prospectus

 

The information called for by Part I of Form S-8 is omitted from this Registration Statement in accordance with Rule 428 of the Securities Act of 1933, as amended (the “Securities Act”), and the instructions to Form S-8. In accordance with the rules and regulations of the Securities and Exchange Commission (the “Commission”) and the instructions to Form S-8, such documents are not being filed with the Commission either as part of this Registration Statement or as prospectuses or prospectus supplements pursuant to Rule 424 under the Securities Act.

 



 

PART II

 

Information Required in the Registration Statement

 

Item 3.         Incorporation of Documents by Reference.

 

The Registrant hereby incorporates by reference into this Registration Statement the following documents previously filed with the Commission:

 

(a)         the Registrant’s prospectus dated July 31, 2014 and filed on August 1, 2014 pursuant to Rule 424(b) under the Securities Act relating to the Registration Statement on Form S-1, as amended (Registration No. 333-197123) (the “Form S-1”), which contains audited financial statements for the Registrant’s latest fiscal year for which such statements have been filed; and

 

(b)         the description of the Registrant’s Common Stock contained in the Registrant’s Registration Statement on Form 8-A (Registration No. 001-36562) filed with the Commission on July 22, 2014, including any amendments or reports filed for the purpose of updating such description.

 

All reports and definitive proxy or information statements filed by the Registrant pursuant to Section 13(a), 13(c), 14 or 15(d) of the Securities Exchange Act of 1934, as amended (the “Exchange Act”) subsequent to the filing of this Registration Statement and prior to the filing of a post-effective amendment which indicates that all securities offered hereby have been sold or which de-registers all securities then remaining unsold shall be deemed to be incorporated by reference into this Registration Statement and to be a part hereof from the date of filing of such documents, except as to documents or information deemed to have been furnished and not filed in accordance with the rules of the Commission.  Any statement contained in a document incorporated or deemed to be incorporated by reference herein shall be deemed to be modified or superseded for purposes of this Registration Statement to the extent that a statement contained in any subsequently filed document which also is deemed to be incorporated by reference herein modifies or supersedes such statement.

 

Item 4.         Description of Securities.

 

Not applicable.

 

Item 5.         Interests of Named Experts and Counsel.

 

Not applicable.

 

Item 6.         Indemnification of Directors and Officers.

 

Section 145 of the Delaware General Corporation Law authorizes a court to award or the Board of Directors of a corporation to grant indemnity to directors and officers in terms sufficiently broad to permit indemnification (including reimbursement of expenses incurred) under certain circumstances for liabilities arising under the Securities Act.

 

As permitted by the Delaware General Corporation Law, the restated certificate of incorporation of the Registrant contains provisions that eliminate the personal liability of its directors for monetary damages for any breach of fiduciary duties as a director, to the fullest extent permitted by law.

 

As permitted by the Delaware General Corporation Law, the restated bylaws of the Registrant provide that (i) the Registrant is required to indemnify its directors and executive officers to the fullest extent permitted by the Delaware General Corporation Law, subject to very limited exceptions; (ii) the Registrant may enter into indemnification contracts with any director, officer, employee or agent of the Registrant; (iii) the Registrant is required to advance expenses, as incurred, to its directors and executive officers in connection with a legal proceeding to the fullest extent permitted by the Delaware General Corporation Law, subject to very limited exceptions; and (iv) the rights conferred in the restated bylaws are not exclusive.

 

In addition, the Registrant has entered into indemnification agreements with each of its current directors and executive officers to provide them with additional contractual assurances regarding the scope of the

 

II-1



 

indemnification set forth in the Registrant’s restated certificate of incorporation and restated bylaws and to provide additional procedural protections.  At present, there is no pending litigation or proceeding involving a director, officer or employee of the Registrant regarding which indemnification is sought, nor is the Registrant aware of any threatened litigation that may result in claims for indemnification.

 

The Registrant currently carries liability insurance for its directors and officers.

 

Reference is also made to the Underwriting Agreement filed with the Form S-1 for the Registrant’s initial public offering, which provides for the indemnification of officers, directors and controlling persons of the Registrant against certain liabilities.

 

The indemnification provision in the Registrant’s restated certificate of incorporation and restated bylaws and the indemnification agreements entered into between the Registrant and each of its directors and executive officers may be sufficiently broad to permit indemnification of the Registrant’s directors and officers for liabilities arising under the Securities Act.

 

See also the undertakings set out in response to Item 9 of this Registration Statement.

 

Item 7.   Exemption from Registration Claimed.

 

Not applicable.

 

Item 8.   Exhibits.

 

Exhibit

 

 

 

Incorporated by Reference

 

Filed

Number

 

Exhibit Description

 

Form

 

File No.

 

Exhibit

 

Filing Date

 

Herewith

 

 

 

 

 

 

 

 

 

 

 

 

 

4.1

 

Restated Certificate of Incorporation of the Registrant, as amended to date.

 

S-1

 

333-197123

 

3.1

 

July 21, 2014

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

4.2

 

Form of Restated Certificate of Incorporation of the Registrant, to be filed immediately after the closing of the offering covered by the Form S-1.

 

S-1

 

333-197123

 

3.2

 

July 21, 2014

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

4.3

 

Bylaws of the Registrant, as currently in effect.

 

S-1

 

333-197123

 

3.3

 

June 30, 2014

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

4.4

 

Form of Restated Bylaws of the Registrant, to be effective immediately after the closing of the offering covered by the Form S-1.

 

S-1

 

333-197123

 

3.4

 

July 21, 2014

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

4.5

 

2013 Equity Incentive Plan and forms of award agreements.

 

S-1

 

333-197123

 

10.2

 

July 30, 2014

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

4.6

 

2014 Equity Incentive Plan and forms of award agreements.

 

S-1

 

333-197123

 

10.3

 

July 21, 2014

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

4.7

 

2014 Employee Stock Purchase Plan

 

S-1

 

333-197123

 

10.9

 

July 21, 2014

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

5.1

 

Opinion and Consent of Fenwick & West LLP.

 

 

 

 

 

 

 

 

 

X

 

 

 

 

 

 

 

 

 

 

 

 

 

23.1

 

Consent of CohnReznick LLP, independent registered public accounting firm.

 

 

 

 

 

 

 

 

 

X

 

 

 

 

 

 

 

 

 

 

 

 

 

23.2

 

Consent of Fenwick & West LLP (contained in Exhibit 5.1).

 

 

 

 

 

 

 

 

 

X

 

 

 

 

 

 

 

 

 

 

 

 

 

24.1

 

Power of Attorney (incorporated by reference to Page II-4 of this Registration Statement).

 

 

 

 

 

 

 

 

 

X

 

II-2



 

Item 9.   Undertakings.

 

A.                                    The undersigned Registrant hereby undertakes:

 

(1)                                 To file, during any period in which offers or sales are being made, a post-effective amendment to this Registration Statement:

 

(i)                                     To include any prospectus required by Section 10(a)(3) of the Securities Act;

 

(ii)                                  To reflect in the prospectus any facts or events arising after the effective date of the Registration Statement (or the most recent post-effective amendment thereof) which, individually or in the aggregate, represent a fundamental change in the information set forth in the Registration Statement.  Notwithstanding the foregoing, any increase or decrease in volume of securities offered (if the total dollar value of securities offered would not exceed that which was registered) and any deviation from the low or high end of the estimated maximum offering range may be reflected in the form of prospectus filed with the Commission pursuant to Rule 424(b) if, in the aggregate, the changes in volume and price represent no more than a 20 percent change in the maximum aggregate offering price set forth in the “Calculation of Registration Fee” table in the effective Registration Statement;

 

(iii)                               To include any material information with respect to the plan of distribution not previously disclosed in the Registration Statement or any material change to such information in the Registration Statement;

 

Provided, however, that paragraphs (a)(1)(i) and (a)(1)(ii) above do not apply if the information required to be included in a post-effective amendment by those paragraphs is contained in periodic reports filed with or furnished to the Commission by the Registrant pursuant to Section 13 or Section 15(d) of the Exchange Act that are incorporated by reference in the Registration Statement.

 

(2)                                 That, for the purpose of determining any liability under the Securities Act, each such post-effective amendment shall be deemed to be a new registration statement relating to the securities offered therein, and the offering of such securities at that time shall be deemed to be the initial bona fide offering thereof.

 

(3)                                 To remove from registration by means of a post-effective amendment any of the securities being registered which remain unsold at the termination of the offering.

 

B.                                    The undersigned Registrant hereby undertakes that, for purposes of determining any liability under the Securities Act, each filing of the Registrant’s annual report pursuant to Section 13(a) or Section 15(d) of the Exchange Act (and, where applicable, each filing of an employee benefit plan’s annual report pursuant to Section 15(d) of the Exchange Act) that is incorporated by reference in the Registration Statement shall be deemed to be a new registration statement relating to the securities offered therein, and the offering of such securities at that time shall be deemed to be the initial bona fide offering thereof.

 

C.                                    Insofar as indemnification for liabilities arising under the Securities Act may be permitted to directors, officers and controlling persons of the Registrant pursuant to the foregoing provisions, or otherwise, the Registrant has been advised that in the opinion of the Commission such indemnification is against public policy as expressed in the Securities Act and is, therefore, unenforceable.  In the event that a claim for indemnification against such liabilities (other than the payment by the Registrant of expenses incurred or paid by a director, officer or controlling person of the Registrant in the successful defense of any action, suit or proceeding) is asserted by such director, officer or controlling person in connection with the securities being registered, the Registrant will, unless in the opinion of its counsel the matter has been settled by controlling precedent, submit to a court of appropriate jurisdiction the question whether such indemnification by it is against public policy as expressed in the Securities Act and will be governed by the final adjudication of such issue.

 

II-3



 

SIGNATURES

 

Pursuant to the requirements of the Securities Act of 1933, the Registrant certifies that it has reasonable grounds to believe that it meets all of the requirements for filing on Form S-8 and has duly caused this Registration Statement to be signed on its behalf by the undersigned, thereunto duly authorized, in the City of Stamford, State of Connecticut, on this 1st day of August, 2014.

 

 

Loxo Oncology, Inc.

 

 

 

 

 

By:

/s/ Joshua H. Bilenker, M.D.

 

 

Joshua H. Bilenker, M.D.

 

 

President, Chief Executive Officer and Director

 

POWER OF ATTORNEY

 

KNOW ALL PERSONS BY THESE PRESENTS, that the undersigned officers and directors of Loxo Oncology, Inc., a Delaware corporation, do hereby constitute and appoint Joshua H. Bilenker, M.D., President, Chief Executive Officer and Director and Dov A. Goldstein, M.D., Chief Financial Officer and Director, the lawful attorneys-in-fact and agents with full power and authority to do any and all acts and things and to execute any and all instruments which said attorneys and agents, and any one of them, determine may be necessary or advisable or required to enable said corporation to comply with the Securities Act of 1933, as amended, and any rules or regulations or requirements of the Securities and Exchange Commission in connection with this Registration Statement.  Without limiting the generality of the foregoing power and authority, the powers granted include the power and authority to sign the names of the undersigned officers and directors in the capacities indicated below to this Registration Statement, to any and all amendments, both pre-effective and post-effective, and supplements to this Registration Statement, and to any and all instruments or documents filed as part of or in conjunction with this Registration Statement or amendments or supplements thereof, and each of the undersigned hereby ratifies and confirms that all said attorneys and agents, or any one of them, shall do or cause to be done by virtue hereof.

 

IN WITNESS WHEREOF, each of the undersigned has executed this Power of Attorney as of the date indicated.

 

Pursuant to the requirements of the Securities Act of 1933, as amended, this Registration Statement has been signed by the following persons on behalf of the Registrant in the capacities and on the dates indicated.

 

Signature

 

Title

 

Date

 

 

 

 

 

/s/ Joshua H. Bilenker, M.D.

 

President, Chief Executive Officer and

 

August 1, 2014

Joshua H. Bilenker, M.D.

 

Director

 

 

 

 

(Principal Executive Officer)

 

 

 

 

 

 

 

/s/ Dov A. Goldstein, M.D.

 

Chief Financial Officer and Director

 

August 1, 2014

Dov A. Goldstein, M.D.

 

(Principal Financial Officer and Principal

 

 

 

 

Accounting Officer)

 

 

 

 

 

 

 

/s/ James Barrett, Ph.D.

 

Director

 

August 1, 2014

James Barrett, Ph.D.

 

 

 

 

 

 

 

 

 

/s/ David, Bonita, M.D.

 

Director

 

August 1, 2014

David, Bonita, M.D.

 

 

 

 

 

 

 

 

 

/s/ Steven A. Elms

 

Director

 

August 1, 2014

Steven A. Elms

 

 

 

 

 

 

 

 

 

/s/ Keith T. Flaherty, M.D.

 

Director

 

August 1, 2014

Keith T. Flaherty, M.D.

 

 

 

 

 

 

 

 

 

/s/ Avi Z. Naider

 

Director

 

August 1, 2014

Avi Z. Naider

 

 

 

 

 

II-4



 

EXHIBIT INDEX

 

Exhibit

 

 

 

Incorporated by Reference

 

Filed

Number

 

Exhibit Description

 

Form

 

File No.

 

Exhibit

 

Filing Date

 

Herewith

 

 

 

 

 

 

 

 

 

 

 

 

 

4.1

 

Restated Certificate of Incorporation of the Registrant, as amended to date.

 

S-1

 

333-197123

 

3.1

 

July 21, 2014

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

4.2

 

Form of Restated Certificate of Incorporation of the Registrant, to be filed immediately after the closing of the offering covered by the Form S-1.

 

S-1

 

333-197123

 

3.2

 

July 21, 2014

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

4.3

 

Bylaws of the Registrant, as currently in effect.

 

S-1

 

333-197123

 

3.3

 

June 30, 2014

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

4.4

 

Form of Restated Bylaws of the Registrant, to be effective immediately after the closing of the offering covered by the Form S-1.

 

S-1

 

333-197123

 

3.4

 

July 21, 2014

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

4.5

 

2013 Equity Incentive Plan and forms of award agreements.

 

S-1

 

333-197123

 

10.2

 

July 30, 2014

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

4.6

 

2014 Equity Incentive Plan and forms of award agreements.

 

S-1

 

333-197123

 

10.3

 

July 21, 2014

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

4.7

 

2014 Employee Stock Purchase Plan

 

S-1

 

333-197123

 

10.9

 

July 21, 2014

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

5.1

 

Opinion and Consent of Fenwick & West LLP.

 

 

 

 

 

 

 

 

 

X

 

 

 

 

 

 

 

 

 

 

 

 

 

23.1

 

Consent of CohnReznick LLP, independent registered public accounting firm.

 

 

 

 

 

 

 

 

 

X

 

 

 

 

 

 

 

 

 

 

 

 

 

23.2

 

Consent of Fenwick & West LLP (contained in Exhibit 5.1).

 

 

 

 

 

 

 

 

 

X

 

 

 

 

 

 

 

 

 

 

 

 

 

24.1

 

Power of Attorney (incorporated by reference to Page II-4 of this Registration Statement).

 

 

 

 

 

 

 

 

 

X

 

II-5


EX-5.1 2 a14-11751_10ex5d1.htm EX-5.1

Exhibit 5.1

 

 

August 1, 2014

 

Loxo Oncology, Inc.

One Landmark Square

Suite 1122

Stamford, CT 06901

 

Gentlemen/Ladies:

 

At your request, we have examined the Registration Statement on Form S-8 (the “Registration Statement”) to be filed by Loxo Oncology, Inc., a Delaware corporation (the “Company”), with the Securities and Exchange Commission (the “Commission”) on or about August 1, 2014 in connection with the registration under the Securities Act of 1933, as amended, of an aggregate of 2,661,304 shares of the Company’s Common Stock, $0.001 par value per share (the “Stock”), subject to issuance by the Company upon the exercise of (a) stock options granted under the Company’s 2013 Equity Incentive Plan, which plan has been terminated and under which no further stock options will be granted, (b) stock options granted or to be granted under the Company’s 2014 Equity Incentive Plan, and (c) purchase rights to be granted under the Company’s 2014 Employee Stock Purchase Plan.  The plans referred to in clauses (a) through (c) in the preceding sentence are collectively referred to in this letter as the “Plans.”  In rendering this opinion, we have examined such matters of fact as we have deemed necessary in order to render the opinion set forth herein, which included examination of the following:

 

(1)                                 the Company’s Amended and Restated Certificate of Incorporation, certified by the Delaware Secretary of State on July 21, 2014 (the “Restated Certificate”);

 

(2)                                 the form of the Company’s Restated Certificate of Incorporation to be filed upon the closing of the offering contemplated by the registration statement on Form S-1, as amended (Registration No. 333-197123) (the “Form S-1”), in connection with the initial public offering of the Stock (the “Post-Effective Restated Certificate”);

 

(3)                                 the Company’s Bylaws, certified by the Company’s Secretary on June 24, 2013 (the “Bylaws”);

 

(4)                                 the form of the Company’s Restated Bylaws to be effective upon the closing of the offering contemplated by the Form S-1 in connection with the initial public offering of the Stock (the “Post-Effective Bylaws”);

 

(5)                                 the Registration Statement, together with the Exhibits filed as a part thereof or incorporated therein by reference;

 

(6)                                 the Plans and related forms of Plan agreements;

 



 

August 1, 2014

Page 2

 

(7)                                 the prospectuses prepared in connection with the Registration Statement (the “Prospectuses”);

 

(8)                                 the minutes of meetings and actions by written consent of the Company’s Board of Directors (the “Board”) and stockholders at which, or pursuant to which, the Restated Certificate, Post-Effective Restated Certificate, Bylaws and Post-Effective Bylaws were approved;

 

(9)                                 the minutes of meetings and actions by written consent of the Board and stockholders at which, or pursuant to which, the Board and stockholders of the Company adopted and approved the Plans, the reservation of the Stock for sale and issuance pursuant to the Plans and the filing of the Registration Statement;

 

(10)                          a statement prepared by the Company as to the number of issued and outstanding options, warrants and rights to purchase shares of the Company’s capital stock and any additional shares of capital stock reserved for future issuance in connection with the Company’s stock option and stock purchase plans and all other plans, agreements or rights as of July 31, 2014;

 

(11)                          a Certificate of Good Standing issued by the Secretary of State of the State of Delaware dated July 31, 2014 (the “Certificate of Good Standing”); and

 

(12)                          an Opinion Certificate addressed to us and dated of even date herewith executed by the Company containing certain factual representations (the “Opinion Certificate”).

 

In our examination of documents for purposes of this opinion, we have relied on the accuracy of representations to us by officers of the Company with respect to the genuineness of all signatures on original documents, the authenticity and completeness of all documents submitted to us as originals, the conformity to originals and completeness of all documents submitted to us as copies, the legal capacity of all persons or entities executing the same, the lack of any undisclosed termination, modification, waiver or amendment to any document referenced in clauses (6), (8) and (9) above to us.

 

The Company’s capital stock is uncertificated.  We assume that issued Stock will not be reissued by the Company in uncertificated form until any previously issued stock certificate representing such issued Stock have been surrendered to the Company in accordance with DGCL Section 158 and that the Company will properly register the transfer of the Stock to the purchasers of such Stock on the Company’s record of uncertificated securities.

 

As to matters of fact relevant to this opinion, we have relied solely upon our examination of the documents referred to above and have assumed the current accuracy and completeness of the information obtained from the documents referred to above and the representations and warranties made by representatives of the Company to us, including but not limited to those set forth in the Opinion Certificate.  We have made no independent investigation or other attempt to

 



 

August 1, 2014

Page 3

 

verify the accuracy of any of such information or to determine the existence or non-existence of any other factual matters.

 

We render this opinion only with respect to, and express no opinion herein concerning the application or effect of the laws of any jurisdiction other than, the existing laws of the United States of America, of the State of California and of the Delaware General Corporation Law, the Delaware Constitution and reported judicial decisions relating thereto.

 

With respect to our opinion expressed in paragraph (1) below as to the valid existence and good standing of the Company under the laws of the State of Delaware, we have relied solely upon the Certificate of Good Standing and representations made to us by the Company.

 

This opinion is based upon the customary practice of lawyers who regularly give, and lawyers who regularly advise opinion recipients regarding, opinions of the kind set forth in this opinion letter, including customary practice as described in bar association reports.

 

Based upon the foregoing, it is our opinion that:

 

(1)                                 The Company is a corporation validly existing, in good standing, under the laws of the State of Delaware; and

 

(2)                                 The 2,661,304 shares of Stock that may be issued and sold by the Company upon the exercise of (a) stock options granted under the Company’s 2013 Equity Incentive Plan, which plan has been terminated and under which no further stock options will be granted, (b) stock options granted or to be granted under the Company’s 2014 Equity Incentive Plan, and (c) purchase rights to be granted under the Company’s 2014 Employee Stock Purchase Plan, when issued, sold and delivered in accordance with the applicable Plan and purchase agreements entered into and to be entered into thereunder and in the manner and for the consideration stated in the Registration Statement and the relevant Prospectus, will be validly issued, fully paid and nonassessable.

 

We consent to the use of this opinion as an exhibit to the Registration Statement and further consent to all references to us, if any, in the Registration Statement, the Prospectus constituting a part thereof and any amendments thereto.

 

This opinion is intended solely for use in connection with issuance and sale of shares subject to the Registration Statement and is not to be relied upon for any other purpose.  This opinion is rendered as of the date first written above and based solely on our understanding of facts in existence as of such date after the aforementioned examination.  We assume no obligation to advise you of any fact, circumstance, event or change in the law or the facts that may hereafter be brought to our attention whether or not such occurrence would affect or modify the opinions expressed herein.

 

 

Very truly yours,

 

 

 

FENWICK & WEST LLP

 

 

 

 

 

By:

/s/ Fenwick & West LLP

 

 

Fenwick & West LLP

 


EX-23.1 3 a14-11751_10ex23d1.htm EX-23.1

Exhibit 23.1

 

Consent of Independent Registered
Public Accounting Firm

 

We consent to the incorporation by reference in this Registration Statement on Form S-8 of Loxo Oncology, Inc. of our report dated May 14, 2014, except for the effects of the matter discussed in Note 11, which is as of July 21, 2014, on our audit of the financial statements of Loxo Oncology, Inc. as of December 31, 2013 and for the period from May 9, 2013 (date of inception) to December 31, 2013, included in Loxo Oncology Inc.’s Registration Statement on Form S-1 (Amendment No. 2).

 

 

/s/ CohnReznick LLP

 

 

 

Roseland, New Jersey

 

July 29, 2014