Cowen and Company, LLC
599 Lexington Avenue, 27th Floor
New York, New York 10022
Stifel, Nicolaus & Company, Incorporated
One Montgomery Street, Suite 3700
San Francisco, California 94104
July 29, 2014
Securities and Exchange Commission
Division of Corporation Finance
100 F Street, N.E.
Washington, D.C. 20549
Attn: |
Larry Spirgel |
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Kathleen Krebs |
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Paul Fischer |
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Re: |
Loxo Oncology, Inc. |
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Registration Statement on Form S-1 |
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Registration File No. 333-197123 |
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Ladies and Gentlemen:
In accordance with Rule 461 under the Securities Act of 1933, as amended (the Act), we, as representatives of the several underwriters, hereby join in the request of Loxo Oncology, Inc. (the Company) for acceleration of the effective date of the above-named Registration Statement so that it becomes effective at 4:00 PM, Washington, D.C. time, on July 31, 2014, or as soon thereafter as practicable, or at such other time as the Company or its outside counsel, Fenwick & West LLP, requests by telephone that such Registration Statement be declared effective.
Pursuant to Rule 460 under the Act, we, as representatives of the several underwriters, wish to advise you that we have effected the following distribution of the Companys Preliminary Prospectus dated July 21, 2014:
(i) Dates of distribution: July 21, 2014 through the date hereof
(ii) Number of prospective underwriters to which the preliminary prospectus was furnished: 4
(iii) Number of prospectuses furnished to investors: approximately 3183
(iv) Number of prospectuses distributed to others, including the Company, the Companys counsel, independent accountants, and underwriters counsel: approximately 180
We, the undersigned, as representatives of the several underwriters, have complied and will comply, and we have been informed by the participating underwriters that they have complied and will comply, with the requirements of Rule 15c2-8 under the Securities Exchange Act of 1934, as amended.
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Very truly yours, | ||
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COWEN AND COMPANY, LLC | ||
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Acting severally on behalf of themselves and the several Underwriters | ||
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By: |
COWEN AND COMPANY, LLC | |
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By: |
/s/ George Milstein | |
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Name: |
George Milstein |
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Title: |
Managing Director |
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By: |
STIFEL, NICOLAUS & COMPANY, INCORPORATED | |
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By: |
/s/ Nicholas Oust | |
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Name: |
Nicholas Oust |
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Title: |
Managing Director |
[Signature Page to Underwriters Acceleration Request]